- Epigenetics and DNA Methylation
- SARS-CoV-2 and COVID-19 Research
- Genetic Associations and Epidemiology
- Vaccine Coverage and Hesitancy
- Liver Disease Diagnosis and Treatment
- Nutrition and Health in Aging
- Gun Ownership and Violence Research
- Suicide and Self-Harm Studies
- Autopsy Techniques and Outcomes
- COVID-19 Clinical Research Studies
- Diverticular Disease and Complications
- Bioinformatics and Genomic Networks
- COVID-19 Impact on Reproduction
- Liver Disease and Transplantation
- Hepatitis C virus research
Boston University
2020-2024
Boston Medical Center
2021-2023
University Medical Center
2023
Sarcopenia is associated with NAFLD. It unknown if the association explained by shared risk factors. Our study sought to investigate between liver fat and sarcopenia in our cohort. Liver was measured on CT 2008 2011. We excluded heavy alcohol use missing covariates. Muscle mass a subset (n = 485) 24 h urinary creatinine. Physical function defined strength walking speed. as low muscle and/or physical function. created multivariable-adjusted regression models evaluate cross-sectional...
Abstract Background Alzheimer’s disease (AD) has both genetic and environmental risk factors. Gene‐environment interaction may help explain some missing heritability. There is strong evidence for cigarette smoking as a factor AD. To identify genetic‐smoking‐related associations with AD, we conducted genome‐wide association study (GWAS) assessing SNP‐smoking stratified analysis by status. Method Lifetime data were available analyzed among 22,030 non‐Hispanic White (NHW; 8,232 cases; 13,798...
Abstract Background Genome‐wide association studies (GWAS) have identified approximately 40 risk loci associated with Alzheimer’s disease (AD). However, only a fraction of heritability has been explained. In large meta‐analysis, smoking was AD dementia. this study, we sought to identify interactions between and single‐nucleotide polymorphisms (SNPs) further characterize genetic architecture. Method We used subset datasets individuals European ancestry from the Disease Genetic Consortium...
Introduction: Current guidelines recommend that patients with iron deficiency anemia (IDA) be considered for bidirectional endoscopy. Heterogeneity in performing terminal ileum (TI) intubation exists among endoscopists when evaluating IDA, and the incremental yield of this maneuver is unknown. We investigated diagnostic TI during workup IDA within a diverse, safety-net hospital population. Methods: performed single-center, retrospective cohort study who underwent ileocolonoscopy evaluation...
Introduction: A recent Gallup poll found that 25% of Americans would decline the COVID-19 vaccine if offered at no cost. Underrepresented minority (URM) and IBD patients historically have lower vaccination rates. We surveyed to identify concerns regarding COVID vaccination, particularly among a URM population. Methods: Participants were recruited from 1265 adult Boston Medical Center (BMC) with diagnosis codes for obtained EMR. Patients sent an electronic survey assessing attitudes Covid-19...