Abstract Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial-like tissues (glands and stroma) located outside uterine cavity. The pathophysiology this condition remains incompletely understood. Local bleeding inflammation within endometriosis lesions, which occur in an environment rich iron, reactive oxygen species (ROS), free radicals, can disturb balance iron peritoneal This disruption trigger oxidative injury response, leading to ferroptosis,...

Tuberculosis (TB) remains a global public health problem. The determination of tuberculosis infection (TBI) using interferon-gamma release assay has now been used widely. We aim to evaluate the positivity rates Standard E TB-Feron enzyme-linked immunosorbent (TB-Feron ELISA) and F fluorescent immunoassay FIA) their agreement with QuantiFERON-TB Gold Plus (QFT-Plus) among TB high-risk populations in Bandung City, Indonesia. conducted cross-sectional study, including people high risk acquiring...

Introduction: Ovarian carcinoma during pregnancy is a rare but clinically significant condition that requires swift and precise management to optimize maternal fetal outcomes. This case report highlights the successful conservative surgical of malignant mucinous ovarian cancer diagnosed in second trimester. It provides insights into feasibility safety intervention pregnancy, contributing valuable evidence existing literature on oncologic care pregnancy.Case Illustration: A 21-year-old woman,...

Purpose: To observe the effect of soya yoghurt (Soyghurt), which is high in flavonoid substance, on expression preeclampsia biomarkers (sFLT-1 and PLGF) serum-induced trophoblast primary cell culture isolated from placental tissue. Methods: The was induced by serum (10%). Soyghurt treatment performed with 2.5%, 5%, 7.5% supernatant concentrations media. markers, sFLT-1 PLGF, were evaluated using ELISA. Results: Expression preeclampsia-induced treated significantly lowered compared to...

Background : Dysmenorrhea or menstrual cramps is the most common complaint among reproductive women in developing countries. The prevalence of dysmenorrhea ranged from 19–91%. Many studies showed that factors associated with include a younger age, nulliparity, family history dysmenorrhea, prolonged duration, high flow, psychological factors, and lifestyle. objective this study was to compare female medical students without regarding profile stress, also examine relationship between stress...

Hyperinsulinemia, a common feature in PCOS, have been found to contribute metabolic disturbance, such as dyslipidaemia and diabetes mellitus type 2. Oral anti-diabetic medications prescribed alleviate this effect. We sought fnd whether DLBS3233, an insulin sensitizer, could women with PCOS high BMI.This study aimed investigate the effect of herbal combination C burmanii L spesiosa extract, on lipid profle, resistance, free testosterone was controlled trial conducted Dr. Cipto Mangunkusumo...

Objective: To assess the effect of short-term gavage ethanolic extract Imperata cylindrica L root on ovarian activity and estrus behavior female mice.Methods: Eighteen virgin ddY mice, 8 to 10 weeks age, weighing 22–25 g with regular cycle, were divided into three groups. Group 1 received 0.5% carboxymethylcellulose, whereas Groups 2 3 at 90 115 mg/kg body weight (b.w.) per day by for 20 days, respectively. All groups checked before 9 a.m. daily vaginal cytology determine phase. On 21, mice...

Background: Dysmenorrhea is a condition of pain during menstruation that may affect daily activities. The phenomenon dysmenorrhea in West Java has reached 54,9%. When not treated, it can decrease productivity at school. This study aimed to find out which therapy was more widely used, the reasons for using therapy, and identify changes non-pharmacological as seen from visual analog scale (VAS) assessment.Methods: research used quantitative data with descriptive conducted cross-sectional...

Introduction: The most common abdominal wall defects are gastroschisis and omphalocele. Gastroschisis is a case of intraabdominal herniation caused by an defect from exposure to amniotic fluid during pregnancy. Omphalocele covered with membranous sac on the umbilical cord’s base. occurred in 1/4000 global birth rate. Prevalence omphalocele between 1/3000 1/5000 cases purpose research present overview patients congenital such as Omphalocele.Method: Research design observational descriptive....

Introduction: The aim of this study is to evaluate the interrelation between neonatal outcome (neonatal asphyxia status) and cardiotocography interpretation during pregnancy.Methods: This an observational analytical employing a cross-sectional approach involving patients delivering at Hasan Sadikin General Hospital in 2023. inclusion criteria were who gave birth with recording 32-37 weeks gestation. exclusion fetal congenital anomalies multiple pregnancy. utilized secondary data from patient...

<title>Abstract</title> Endometriosis involves the presence of endometrial-like tissue outside uterus, driven by inflammatory pathways including elevated Interleukin-32 (IL-32) and Vascular Endothelial Growth Factor (VEGF). One potential anti-inflammatory agent is active vitamin D (1,25(OH)2D3). This research investigates correlation among 1,25(OH)2D3 levels, IL-32, VEGF in 46 confirmed endometriosis cases. Tissue samples were collected from patients at several hospitals, assays conducted...

Introduction : Secondary amenorrhea which caused by intrauterine adhesions is called Asherman's syndrome. This occurs when the uterine cavity becomes partially or completely blocked, can damage basal layer of endometrium and cause formation adhesive cicatricial tissue. The prevalence incidence Asherman Syndrome ranges from 2.84-5.5% in women. Case Report A woman 33 years old had a history for 2 three times curettage due to miscariage. Ultrasound findings showed 1.35 cm long cicatrix cavity,...

Introduction: Congenital abnormalities are anomalies that become a fear for family, when mother experiences pregnancy. Some temporary and can be corrected, while some permanent cannot so screening at antenatal time is very important.Objective: To explain analyze rare case of Tetra-amelia syndrome how to diagnose it.Case: A 32-year-old woman with 32-week-old G3P0A2 pregnancy visited the maternal-fetal clinic. According ultrasound data, single fetus gestational age 31-32 weeks fetal weight...

Objectives: Recently, there has been a decline in the use of vacuums and forceps. This is due to complications that occur mother baby as well operator’s ability operate instruments. Concerning Professional Education Standards for Obstetrics Gynecology Specialists, minimum skill must be achieved by vacuum extraction forceps five cases. difficult achieve with number obstetrics gynecology residents West Java. Methods: A retrospective study was conducted using medical records based on...

The incidence of new cases thyroid cancer worldwide is around 10.1/100.000 in woman dan 3.1/100.000 men. Women with are advised to avoid pregnancy while undergoing radioablation due teratogenicity. Therefore, it crucial utilize contraception during treatment. purpose this study was determine the characteristics contraceptive use patterns women reproductive age who underwent at Hasan Sadikin Hospital Bandung.Cross-sectional conducted Bandung May 2023. research sample all female Nuclear...

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Objectives: Numerous studies have been performed on the effect of L-arginine supplementation improving maternal outcomes, but impact L-citrulline in pregnancy are limited. This study aimed to evaluate level pregnant adolescents with severe preeclampsia compared those without preeclampsia. Materials and Methods: is a cross-sectional among 60 adolescent women giving birth Emergency Room Delivery Hasan Sadikin Hospital, Bandung, Indonesia from May October 2020. The levels were examined (n = 30)...

Abstrak Tujuan : Mengetahui hasil luaran tindakan operatif pada kanker serviks, endometrium dan ovarium di RSUP Dr. Hasan Sadikin. Metode Jenis penelitian dengan mengevaluasi data pasien dari Bagian Rekam Medik Sadikin, Bandung Januari 2015−Desember 2016. Variabel yang dievaluasi berupa usia, BMI, paritas, asal kanker, jenis komplikasi operasi. Hasil Terdapat 560 kasus sesuai kriteria inklusi Nilai tengah usia 45 tahun, 222 (39,6%) memiliki BMI normal 413 (73,8%) ovarium. Perdarahan >2000 cc...

We aimed to analyze the relationship between estradiol level and thromboelastography profile.This prospective study with comparative analysis was performed on nineteen samples undergoing an IVF procedure in two fertility clinics Bandung city. Blood taken second twelfth days of cycle.There were significant differences value estradiol, fibrin formation time (α), coagulation index (CI) (p<0.05). Correlation tests showed no correlation increased (rs=0.054; p=0.827) fibrinolysis (LY30)...

Abstrak Tujuan : Mengetahui hasil luaran tindakan operatif pada kanker serviks, endometrium dan ovarium di RSUP Dr. Hasan Sadikin. Metode Jenis penelitian dengan mengevaluasi data pasien dari Bagian Rekam Medik Sadikin, Bandung Januari 2015−Desember 2016. Variabel yang dievaluasi berupa usia, BMI, paritas, asal kanker, jenis komplikasi operasi. Hasil Terdapat 560 kasus sesuai kriteria inklusi Nilai tengah usia 45 tahun, 222 (39,6%) memiliki BMI normal 413 (73,8%) ovarium. Perdarahan &gt;2000...

Abstrak Tujuan : Penelitian ini bertujuan untuk membandingkan perbedaan kadar 25-hidroksi-vitamin D3 pada serum kelompok mioma uteri dan non-mioma uteri. Metode merupakan penelitian analitik observasional dengan rancangan komparatif cross sectional. Subjek adalah wanita usia reproduksi yang menjalani prosedur laparatomi/laparaskopi memenuhi kriteria inklusi (n=42). dibagi menjadi dua kelompok, yakni (n=21) (n=21). Pada kedua dilakukan pemeriksaan kemudian diperiksa metode...

To provide characteristics and hormonal profiles of secondary amenorrhea cases in adolescent patients treated at Hasan Sadikin General Hospital Bandung.The study was retrospective nature involved the analysis medical records from 2017 to 2022 for 44 aged 10-18 who had amenorrhea.There were adolescents included this after excluded 69 adults 113 cases. The majority 14-17 years old (38.63%), senior high school (45.45%), started menarche 11 normal nutritional status (65.91%), stature (65.91%)....

Objective: To identify the characteristics of endometrioma recurrence cases. Method: This study was a descriptive retrospective, using secondary data taken from all medical records Clinic Aster and Medical Records Installation in Dr. Hasan Sadikin General Hospital, Bandung, 1st January 2018 – 31st December 2022. Data were presented tables. Results: Of 37 recurrences, most patients are 20 to 35 age. None them has parity history after first surgical procedure. Both previous recent cases...