A5002525864- Olfactory and Sensory Function Studies
- Advanced Chemical Sensor Technologies
- Biochemical Analysis and Sensing Techniques
- Functional Brain Connectivity Studies
- Action Observation and Synchronization
- Neural dynamics and brain function
- Neurobiology and Insect Physiology Research
- Multisensory perception and integration
- Color perception and design
- Blind Source Separation Techniques
- Sensory Analysis and Statistical Methods
- Child and Animal Learning Development
- Language and cultural evolution
- Advanced Neuroimaging Techniques and Applications
- Cognitive Science and Mapping
- Neural and Behavioral Psychology Studies
- Bioinformatics and Genomic Networks
- Nutrition and Health in Aging
- Regulation of Appetite and Obesity
- Face Recognition and Perception
- Neural Networks and Applications
- Spatial Cognition and Navigation
- Neurological Disease Mechanisms and Treatments
- Cell Image Analysis Techniques
- Peripheral Neuropathies and Disorders
Université Claude Bernard Lyon 1
2016-2025
Centre National de la Recherche Scientifique
2016-2025
Inserm
2015-2025
Centre de Recherche en Neurosciences de Lyon
2016-2025
Laboratoire d’Étude des Mécanismes Cognitifs
2010-2025
Centre d'Exploration et de Recherche Médicale par Emission de Positons
2024
Institut Universitaire de France
2024
Centre Hospitalier Le Vinatier
2019-2024
Université Lumière Lyon 2
2024
King's College London
2012-2013
Olfaction is characterized by a salient hedonic dimension. Previous studies have shown that these affective responses to odors are modulated physicochemical, physiological, and cognitive factors. The present study examined expertise influenced processing of pleasant unpleasant on both perceptual verbal levels. For this, performance two olfactory tasks was compared between novices, trainee cooks, experts (perfumers flavorists): Members all groups rated the intensity pleasantness (perceptual...
Autism Spectrum Disorders (ASDs) are characterized by atypical sensory functioning in the visual, tactile, and auditory systems. Although less explored, olfactory changes have been reported ASD patients. To explore these on a neural level, 18 adults with healthy neurotypical controls were examined 2-phase study. Participants first tested for odor threshold identification. Then, (i) structural magnetic resonance (MR) images of bulb acquired, (ii) functional MR imaging olfaction study was...
An important goal in researching the biology of olfaction is to link perception smells chemistry odorants. In other words, why do some odorants smell like fruits and others flowers? While so-called stimulus-percept issue was resolved field color vision time ago, relationship between psycho-biology odors remains unclear up present day. Although a series investigations have demonstrated that this exists, descriptive explicative aspects proposed models are currently use require greater...
Body odors play an important role in nonverbal communication, and particularly one's attractiveness. However, their central processing remains underexplored, especially as a function of gender. This study aims at identifying the neural networks involved two allegedly sex-specific human body odor compounds (3-hydroxy-3-methylhexanoic acid, HMHA, 3-methyl-3-sulfanylhexan-1-ol, MSH). We hypothesized that i) these would be processed by different brain regions than non-body odors, ii)...
Music is one of the most pleasurable stimuli in humans’ life, often experienced social contexts where shared enjoyment can amplify emotional responses. Despite its significance, neural and affective mechanisms underlying socially music remain largely unexplored. Using hyperscanning fNIRS, we examined musical pleasure friend dyads (N=34) who listened to favorite experimenter-selected either alone or together. Joint listening significantly increased pleasure, particularly for friend’s music,...
What is known as an odor object integrated representation constructed from physical features, and perceptual attributes mainly mediated by the olfactory trigeminal systems. The aim of present study was to comprehend how this multidimensional organized, deciphering similarities in physical, spaces odors are represented human brain. To achieve aim, we combined psychophysics, functional MRI multivariate representational similarity analysis. Participants were asked smell diffused fMRI-compatible...
Abstract A major issue in human olfaction research is to characterize the main dimensions that organize space of odors. The present study examines this question and shows that, beside pleasantness, trigeminal sensations, particularly irritation, play an important role. These results were consistent along two different spaces constructed using semantic description physiological responses 105 odorants, smelled described by participants. Taken together, these findings suggest salient features,...
Comparing networks in neuroscience is hard, because the topological properties of a given network are necessarily dependent on number edges that network. This problem arises analysis both weighted and unweighted networks. The term density often used this context, order to refer mean edge weight network, or an one. families therefore statistically difficult differences topology associated with density. In review paper, we consider from two different perspectives, which include (i)...
Abstract Although olfactory disorders (OD) are among the most significant symptoms of COVID-19, recovery time from COVID-19-related OD and their consequences on quality life remain poorly documented. We investigated characteristics behavioral using a large-scale study involving 3111 French respondents (78% women) to an online questionnaire over period 9 months covering different epidemic waves (from 8 April 2020 13 January 2021). In patients who subjectively recovered (N = 609), occurred...
The ability to regulate appetite is essential avoid food over-consumption. desire for a particular can be triggered by its odor before it even seen. Using fMRI, we identify the neural systems modulated cognitive regulation when experiencing appetizing stimuli presented in both olfactory and visual modalities, while being hungry. Regulatory instruction bids items inhalation patterns. Distinct brain regions were observed up down appetite-regulation, respectively dorsomedial prefrontal cortex...
Abstract Emotions can be communicated in social contexts through chemosignals contained human body odors. The transmission of positive emotions via these signals has received little interest past research focused mainly on negative emotional transmission. Furthermore, how the use perfumed products might modulate this remains poorly understood. To investigate chemical communication, we explored autonomic, verbal, and behavioral responses receivers exposed to odors donors having undergone a...
Body odors convey information about the individuals, but mechanisms are not fully understood yet. As far as human reproduction is concerned, molecules that produced in sexually dimorphic amounts could be possible chemosignals. 3-hydroxy-3-methylhexanoic acid (HMHA) one of them—more typical men. Here, we investigated possibility perception gender and attractiveness faces implicitly influenced by this compound. Clearly feminine, ambiguous clearly masculine were primed with an odor HMHA, a...
Abstract Cumulative technological culture is defined as the increase in efficiency and complexity of tools techniques over generations. While role social cognitive skills cultural transmission has been long acknowledged, recent accounts have emphasized that non-social such technical reasoning, a form causal reasoning aimed at understanding physical world, are also work during content. Here we contribute to this double process approach by reporting an fMRI study about neurocognitive origins...
Semantic description of odors is a cognitively demanding task. Learning to name smells is, however, possible with training. This study set out examine how improvement in olfactory semantic knowledge following training reorganizes the neural representation smells. First, 19 nonexpert volunteers were trained for 3 days; they exposed (i) odorants presented without verbal labels (perceptual learning) and (ii) other paired lexicosemantic (associative learning). Second, same participants tested...
Sniffing, which is the active sampling of olfactory information through nasal cavity, part percept. It influenced by stimulus properties, affects how an odor perceived, and sufficient (without being present) to activate cortex. However, many aspects affective correlates sniffing behavior remain unclear, in particular modulation volume duration as a function hedonics. The present study used wide range odorants with contrasted hedonic valence test: (1) psychophysical best describes...
Studies of functional MRI data are increasingly concerned with the estimation differences in spatio-temporal networks across groups subjects or experimental conditions. Unsupervised clustering and independent component analysis (ICA) have been used to identify such networks. While these approaches useful for estimating at subject-level, comparisons over conditions require further methodological development. In this paper, we tackle problem by showing how self-organizing maps (SOMs) can be...
Studies of olfaction in Alzheimer's disease (AD) mainly focused on deficits odor detection and identification, with very few investigations olfactory emotional changes their consequences for hedonics.The aim the present study was to characterize affective evaluations odors AD patients.To this end, 20 patients matched controls were tested. Participants screened identification ability then asked rate intensity, pleasantness, edibility odorants.Results showed that, overall, had lower perceived...