- Renal Diseases and Glomerulopathies
- Heart Rate Variability and Autonomic Control
- Vasculitis and related conditions
- Eosinophilic Esophagitis
- Non-Invasive Vital Sign Monitoring
- Urticaria and Related Conditions
- Neonatal and fetal brain pathology
- Neonatal Respiratory Health Research
- Otitis Media and Relapsing Polychondritis
- Environmental Science and Water Management
- Air Quality Monitoring and Forecasting
- Congenital Diaphragmatic Hernia Studies
- Indoor Air Quality and Microbial Exposure
- Esophageal and GI Pathology
- Tracheal and airway disorders
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Air Quality and Health Impacts
- Respiratory Support and Mechanisms
- Advanced Glycation End Products research
- Human Health and Disease
- Hemophilia Treatment and Research
- COVID-19 Impact on Reproduction
- Agricultural and Rural Development Research
- IL-33, ST2, and ILC Pathways
- Study of Mite Species
University of Osijek
2018-2025
Klinički bolnički centar Osijek
2020-2024
University Hospital Centre Zagreb
2020-2021
University of Zagreb
2021
University of Split
2021
Klinički Bolnički Centar Rijeka
2021
Institute of Public Health Osijek-Baranja County
2014
Heart rate variability (HRV) has been analysed using linear and nonlinear methods. In the framework of a controlled neonatal stress model, we applied tone–entropy (T–E) analysis at multiple lags to understand influence external stressors on healthy term neonates. Forty neonates were included in study. HRV was multi-lag T–E two resting phases (heel stimulation heel stick blood drawing phase). Higher mean entropy values lower tone when stressed showed reduction randomness with increased...
Studies concerning the genetic background of IgA vasculitis (IgAV), a small-vessel occurring predominantly in childhood, have confirmed that HLA-DRB1 gene showed strong association with disease susceptibility. The objective was to investigate human leukocyte antigen (HLA) polymorphisms among Croatian patients IgAV and their influence on susceptibility clinical heterogeneity. Thus, 130 children 202 unrelated healthy individuals were enrolled study. Genomic DNA extracted from whole peripheral...
Research on spatial variability of the incidence IgA vasculitis (IgAV) in children and its potential implications for elucidation multifactorial aetiology pathogenesis is limited. We intended to observe IgAV vasculitis-associated nephritis (IgAVN) using modern geostatistical methods, hypothesised that their distribution may be spatially clustered.Patients' data were retrospectively collected from 2009 2019 five Croatian University Hospital Centres paediatric rheumatology, census used...
<b><i>Background/Objective:</i></b> The purpose of this study was to evaluate the prevalence and severity skin involvement in children with IgA vasculitis (IgAV) its relationship clinical biochemical parameters risk developing nephritis (IgAVN), only cause long-term morbidity main prognostic factor IgAV patients. <b><i>Methods:</i></b> This national multicenter retrospective included 611 patients under age 18 years referred five Croatian...
We analysed clinical and biochemical parameters in predicting severe gastrointestinal (GI) manifestations childhood IgA vasculitis (IgAV) the risk of developing renal complications.A national multicentric retrospective study included children with IgAV reviewed five Croatian University Centres for paediatric rheumatology period 2009-2019.Out 611 children, 281 (45.99%) had at least one GI manifestation, while 42 (14.95%) most manifestations. Using logistic regression several factors were...
We aim at detecting stress in newborns by observing heart rate variability (HRV). The HRV features nonlinearities. Fractal dynamics is a usual way to model them and the Hurst exponent summarizes fractal information. In our framework, we have observations of short duration, for which estimators exponent, like detrended fluctuation analysis (DFA), are not adapted. Moreover, observe that does vary much between rest phases, but its decomposition memory underlying properties probability...
To detect stress in newborns by observing heart rate (HR) variability utilizing an asymmetric detrended fluctuation analysis (ADFA), we sought to determine the fractal structure of series inter-beat intervals, so as distinguish periods acceleration HR from decelerations. Thus, two scaling exponents, α + and -, representing decelerations accelerations respectively, are obtained.Forty healthy term were included this study, undergoing different types stimuli: routine heel lance blood sampling...
In this early pilot study, we sought to determine if the alteration in these physiologic efects premature infants response ambient noise NICU could be assessed evaluating cerebral blood saturation. Tree infants, on high fow nasal cannula oxygen support (HFNC), at less than 34 weeks of gestation were included study. variables were used evaluate sound levels due AAP and EPA guidelines; Leq,1h, L10,1h Lmax,1min. All patients studied found exposed statistically signifcant (above...
Abstract Aware that exposure to stuffy indoor air with high levels of carbon dioxide (CO 2 ) is associated higher absenteeism and reduced academic performance in school pupils, the World Health Organization (WHO) Regional Office for Europe initiated quality surveys schools, including CO monitoring, assess ventilation air. Here we report findings first such survey Croatia. It was conducted 60 classrooms 20 urban rural elementary schools throughout country during heating season. Measurements...
Abstract Background Atelectasis is a condition characterized by the collapse and nonaeration of lung regions considered manifestation an underlying disease process. The goal atelectasis treatment restoration volume loss. In range different options, chest physiotherapy often used as first‐line approach, some cases require bronchoscopic interventions. Methods this case series, we describe modified procedure using pressure‐controlled segmental insufflation with surfactant application. Results...
The aim of this study was to examine the impact pentraxin 3 (PTX3) serum level and angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism on severity radiographic pulmonary infiltrates clinical outcomes COVID-19.
This study aimed to compare the renal resistive index (RI) as an early marker of damage between normoalbuminuric children with type 1 diabetes mellitus (T1D) and normal age-matched controls. A total 76 T1D (aged 10-18 years) healthy controls were enrolled. Anthropometric parameters, blood pressure, glycated hemoglobin (HbA1c), serum creatinine (sCr), estimated glomerular filtration rate (eGFR), uric acid (SUA), urine albumin/creatinine ratio (ACR), degree pubertal development determined in...
Endothelial cell injury is a hallmark of IgA vasculitis (IgAV), possibly associated with various factors, including oxidative stress. Certain single nucleotide polymorphisms (SNPs) glutathione S-transferases (GST) genes have been shown to increase susceptibility The objective our study was evaluate the gene GSTM1, GSTT1, GSTP1, and GSTA1 in patients IgAV. DNA extracted from blood 124 children IgAV 168 age-matched healthy controls. A higher frequency GSTM1 null genotype observed...