A5035149036- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Chemotherapy-induced cardiotoxicity and mitigation
- Healthcare Systems and Technology
- Advanced X-ray and CT Imaging
- Vascular Procedures and Complications
- Cancer survivorship and care
- Cancer Treatment and Pharmacology
- Cardiac Structural Anomalies and Repair
- Cardiovascular Disease and Adiposity
- Acute Myocardial Infarction Research
- Patient Satisfaction in Healthcare
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer-related cognitive impairment studies
- Lysosomal Storage Disorders Research
- Patient-Provider Communication in Healthcare
- Streptococcal Infections and Treatments
- Atrial Fibrillation Management and Outcomes
- Antimicrobial Resistance in Staphylococcus
- Advanced MRI Techniques and Applications
- Heart Failure Treatment and Management
- Transplantation: Methods and Outcomes
- Biomarkers in Disease Mechanisms
Centro de Investigación Biomédica en Red
2019-2024
Centro de Investigación en Red en Enfermedades Cardiovasculares
2019-2024
Complejo Hospitalario Universitario de Santiago
2010-2024
Universidade de Santiago de Compostela
2012-2024
Instituto de Investigación Sanitaria de Santiago
2021-2024
Servicio Gallego de Salud
2021-2024
Centre for Biomedical Network Research on Rare Diseases
2021
Instituto de Salud Carlos III
2020
Complexo Hospitalario Universitario A Coruña
2019
Abstract Aims Current guidelines recommend sacubitril/valsartan for patients with heart failure and reduced left ventricular ejection fraction (LVEF), but there is lack of evidence its efficacy safety in cancer therapy‐related cardiac dysfunction (CTRCD). Our aim was to analyse the potential benefit CTRCD. Methods results We performed a retrospective multicentre registry (HF‐COH) six Spanish hospitals cardio‐oncology clinics including all treated sacubitril/valsartan. Demographic clinical...
Breast cancer (BC) treatment with anthracyclines and/or anti-human epidermal growth factor receptor-2 (HER2) antibodies is associated an increased risk of cardiovascular disease complications, including therapy-related cardiac dysfunction (CTRCD). While Cardio-Oncology Rehabilitation (CORe) programs exercise have emerged to minimize these risks, its role in preventing CTRCD unclear.
Abstract Purpose To determine whether the 30-s sit-to-stand (30STS) test can be a valid tool for estimating and stratifying peak oxygen uptake (VO2peak) 6-min walking distance (6MWD) in women with breast cancer. Methods This cross-sectional study uses data from ONCORE randomized controlled trial, including 120 aged 18–70 years early-stage cancer under treatment anthracycline and/or anti-HER2 antibodies. Participant characteristics were collected at baseline pooled functional assessment...
Abstract Background Anthracyclines and monoclonal antibodies against human epidermal growth factor receptor-2 (HER2) are frequently used to treat breast cancer but they associated with risk of developing cardiotoxicity. Implementation cardioprotective strategies as part treatment needed. To date, a limited number studies have examined the effectiveness cardiac rehabilitation programs or exercise in prevention cardiotoxicity through an integral assessment function. The ONCORE study proposes...
Abstract Aims We aimed to assess longer-term results (accessibility, hospital admissions, and mortality) in elderly patients referred a cardiology department (CD) from primary care using e-consultation outpatient care. Methods included 9963 >80 years 1 January 2010 31 December 2019. Until 2012, all attended an in-person consultation (2010–2012). In 2013, we instituted e-consult programme (2013–2019) for referrals cardiologists that preceded patient’s when considered. used interrupted...
Left ventricular ejection fraction (LVEF) recovery after an ST-segment elevation myocardial infarction (STEMI) identifies a group of patients with better prognosis. However, the association between long-term outcomes and LVEF among STEMI undergoing primary percutaneous coronary intervention (PCI) has not yet been well investigated. Our study aims to detect differences in all-cause cardiovascular mortality who recover at 1-year post-PCI those do not, search for predictors recovery.This is...
Abstract Aim The relative apical sparing pattern of left ventricular (LV) longitudinal strain (RELAPS]>1) has been described as a typical sign cardiac amyloidosis (CA). objective was to validate this in concomitant CA and aortic stenosis (AS) identify new echocardiographic variables suggestive the presence AS. Methods Results 324 consecutive patients (age 81.5±5.8 years, 51% women) with AS who underwent transcatheter valve implantation (TAVI) were prospectively included....
Introduction We evaluate the ability of 2D non‐contrast‐enhanced echocardiography ( CE ‐echo), 2 DCE ‐echo, 3D‐echo, 3D non‐ and 3 ‐echo to allograft function dimensions in orthotropic heart transplantation OHT ). Cardiac resonance CMR ) was used as reference. Methods Twenty six consecutive ‐recipients were prospectively recruited. Bland–Altman, Spearman rank, concordance‐correlation coefficients CCC determined. Results Good s found between four modalities for ejection fraction r ≥ 0.72/ P...
The aim of the present study was to determine long-term prognostic value provided by exercise electrocardiographic (ECG) response nuclear myocardial perfusion imaging (MPI) in evaluation patients with chest pain, focusing on a discrepancy between two tests. A total 1460 consecutive (777 female; 62.6±11.4 years) undergoing single-photon emission computed tomography (SPECT) were included. endpoint occurrence acute coronary syndrome, heart failure or cardiac death during follow-up. Ischemic ECG...
Abstract Background and Purpose A longitudinal strain pattern characterized by apical sparing (RELAPS>1) has been identified as indicative of cardiac amyloidosis (CA). We conducted an analysis to assess its diagnostic accuracy in individuals with severe aortic stenosis (AS) explored novel echocardiographic variables for predictive value. Methods All patients diagnosed AS who underwent transcatheter valve implantation (TAVI) were prospectively enrolled. 2D-Speckle-tracking...
Abstract Introduction Cardiovascular toxicity (cardiotoxicity) is recognized as a major side-effect of cancer therapies. As early diagnosis and management crucial in clinical practice1,2, knowledge about risk factors scores scarce3,4. Purpose The aim this study to develop prediction score identify patients at high/very high cardiotoxicity. Methods CARDIOTOX registry5,6 included receiving therapies related moderate/high for cardiotoxicity (2012-2017). Clinical, laboratory echo parameters were...
The p.Arg301Gln variant in the α -galactosidase A gene (GLA) has been poorly described literature. few reports show controversial information, with both classical and nonclassical Anderson–Fabry Disease (AFD) presentation patterns. aim of this study was to analyze penetrance, clinical phenotype, biochemical profile an international cohort patients carrying genetic GLA gene. This observational, international, retrospective case series associated AFD disease. Forty-nine carriers, 41% male,...
The aim of the present study was to determine long-term prognostic value provided by exercise electrocardiographic (ECG) response nuclear myocardial perfusion imaging (MPI) in evaluation patients with chest pain, focusing on a discrepancy between two tests. A total 1460 consecutive (777 female; 62.6±11.4 years) undergoing single-photon emission computed tomography (SPECT) were included. endpoint occurrence acute coronary syndrome, heart failure or cardiac death during follow-up. Ischemic ECG...