- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Ovarian cancer diagnosis and treatment
- Urinary Tract Infections Management
- Anorectal Disease Treatments and Outcomes
- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Pelvic and Acetabular Injuries
- Urological Disorders and Treatments
- Intraperitoneal and Appendiceal Malignancies
- Ectopic Pregnancy Diagnosis and Management
- Wave and Wind Energy Systems
- Hernia repair and management
- Minimally Invasive Surgical Techniques
- Pregnancy-related medical research
- Gynecological conditions and treatments
- Coastal and Marine Dynamics
- Colorectal and Anal Carcinomas
- Maternal and fetal healthcare
- Ureteral procedures and complications
- Cervical Cancer and HPV Research
- Maternal and Perinatal Health Interventions
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
Tzu Chi University
2024
Far Eastern Memorial Hospital
2015-2024
National Taiwan University Hospital
2008-2024
Yuan Ze University
2017-2024
Stanford University
2023
National Taiwan University
1993-2021
National Yang Ming Chiao Tung University
2018
China Medical University
2016
American Society of Clinical Oncology
2016
Chang Gung University
2016
Classic signaling by the proinflammatory cytokine interleukin 6 (IL-6) involves its binding to target cells that express membrane-bound IL-6 receptor α. However, an alternate pathway exists in which soluble (sIL-6Rα) can bind and activate lack mIL-6Rα, such as endothelial cells. This pathway, also termed trans-signaling, serves major various pathologic conditions including cancer. Here we report sIL-6Rα is elevated malignant ascites from ovarian cancer patients, where it associated with poor...
Abstract. Nitrification is a series of processes that oxidizes ammonia to nitrate, which contributes hypoxia development in coastal oceans, especially eutrophicated regions. The nitrification rate bulk water (NRb) and particle free (NRpf, > 3 μm eliminated) were determined along the Chang Jiang River plume August 2011 by nitrogen isotope tracer technique. Measurements dissolved oxygen (DO), community respiration (CR), nutrients, organic (DON), total suspended matter (TSM), particulate...
This retrospective study is aimed to present videourodynamic findings of women with symptoms voiding dysfunction in a medical center. Of 1914 women, the diagnoses included bladder outlet obstruction (BOO, n = 810, 42.3%), (n 1,048, 54.8%) and normal tracings 56, 2.9%). Anatomic BOO 49) cystocele 19) urethral stricture 30). Common functional BOOs dysfunctional 325, 17.0%) poor relaxation external sphincter 336, 17.6%). subtypes detrusor underactivity 337, 17.6%), hyperactivity impaired...
Abstract Objective: To understand prevalence, severity, impact, and treatment of vasomotor symptoms associated with menopause, using cross-sectional survey data. Methods: This online, two-part was conducted in East Asia among women 40-65 years recruited from established online panels (Edelman, Beijing; Hankook Research, Seoul; Rakuten Insight, Taipei) stratified sampling. Part I collected demographics/disease characteristics, including menopausal status symptom severity. Women...
To evaluate the correlations among Overactive Bladder Symptom Score (OABSS), International Prostate Score-Storage Subscore (IPSS-S), and modified Urgency Severity Scale (USS) in patients with overactive bladder (OAB) hypersensitive (HSB) to identify most useful diagnostic tool for classifying severity of OAB.We retrospectively reviewed charts consecutive OAB who visited our urologic clinics treatment. All underwent a detailed history, physical examination, urinalysis, uroflowmetry, postvoid...
Objectives To analyze the predictors of therapeutic efficacy after intravesical botulinum toxin A injection for overactive bladder syndrome (OAB) refractory to antimuscarinic therapy. Methods All consecutively OAB patients, who visited urologic outpatient clinics a medical center and treatment, were prospectively enrolled. enrolled patients received 100 U onabotulinumtoxinA (Botox). The Global Response Assessment (GRA) score ≥ 2 at 3 months Botox was defined as successful otherwise failed....
We aimed to identify prognostic factors of early-stage cervical adenocarcinoma (AC) and adenosquamous carcinoma (ASC) treated with primary radical surgery, evaluate the impact postoperative adjuvant therapy on outcome.The clinical-pathological data all patients (n = 1132) stages I-II AC/ASC surgery at member hospitals Taiwanese Gynecologic Oncology Group were retrospectively reviewed.In multivariate analysis, stage II, deep stromal invasion (DSI), lymphovascular space (LVSI), positive pelvic...
The benefit of robot-assisted laparoscopic myomectomy (RALM) over traditional (TLM) remains undetermined. aim this study was to reveal any potential advantage RALM TLM.Between June 2010 and October 2011, all women presenting with symptomatic uterine myomas were enrolled in study. Perioperative variables compared between these two groups. patients recruited allocated into the groups based on their financial considerations.A total 42 received (n = 20) or TLM 22) for myomas. operation time...
Previous studies evaluating the situation-background-assessment-recommendation (SBAR) have been shown to increase effective nurse-physician communication and collaboration. The purpose of this study is evaluate impact SBAR technique on safety attitudes in obstetrics department.This implemented Collaborative Communication Education course was conducted a medical center from February 2012 March 2015, which included an educational session fetal heart rate monitoring, case-based discussion,...
Female voiding dysfunction with cystocele have been widely studied, but there are no data regarding women without cystoceles. The present study aimed to evaluate the prevalence of detrusor underactivity (DU) and bladder outlet obstruction (BOO) cystoceles in a large sample size.
Pelvic-floor muscle (PFM) strengthening has been widely used to treat people with urinary incontinence (UI). However, its effect on bladder neck position and stiffness is unknown.The aim of the study was investigate PFM mobility for women stress UI (SUI) or mixed (MUI).This conducted as a single-group pretest-posttest design.This mainly at Life Quality & Health Promotion Laboratory National Taiwan University partly in Ultrasonography Room Department Obstetrics Gynecology Hospital. Patients...
Abstract Background To review the experience and to evaluate treatment plan of using helical tomotherapy (HT) for cervical cancer. Methods Between November 1st, 2006 May 31, 2009, 10 cancer patients histologically confirmed were enrolled. All received definitive concurrent chemoradiation (CCRT) with whole pelvic HT (WPHT) followed by brachytherapy. During WPHT, all treated cisplatin, 40 mg/m 2 intravenously weekly. Toxicity was scored according Common Terminology Criteria Adverse Events v3.0...
Abstract Aim: To evaluate the urodynamic effects, therapeutic efficacy and safety of solifenacin versus tolterodine treatment for women with overactive bladder syndrome. Methods: Patients were randomized to receive either 5 mg or ER 4 once a day 12 weeks at each four‐week visit in post‐marketing study. Only (solifenacin [ n = 26] vs. 22]) included this subgroup analysis. Adverse events changes values clinical data compared between groups. Results: The volume voided per micturition increased...
Abstract Background Stereotactic body radiation therapy (SBRT) administered via a helical tomotherapy (HT) system is an effective modality for treating lung cancer and metastatic liver tumors. Whether SBRT delivered HT feasible alternative to brachytherapy in treatment of locally advanced cervical patients with unusual anatomic configurations the uterus has never been studied. Case Presentation A 46-year-old woman presented 8-month history abnormal vaginal bleeding. Biopsy revealed squamous...
Background: To compare the short-term outcome of patients undergoing single-port laparoscopic salpingectomy (SP-LS) and conventional three-port (C-LS). Methods: A retrospective evaluation 112 with tubal pregnancies treated by one surgeon at a single teaching hospital. Among these, 47 were SP-LS remaining 65 C-LS. Results: The characteristics similar in both groups. There no statistically significant differences operative time, estimated blood loss, intraoperative immediate postoperative...
Abstract Aims The aim of the study is to compare efficacy an 8‐week pelvic floor muscle training program with surface electromyography feedback, performed in different body positions (supine, sitting, and standing), women stress urinary incontinence. Design This a prospective observational January 2014 May 2016. Methods was by 110 incontinence, each completing 4 individual sessions. main outcome activity muscles synergistic abdominal muscles. Outcome measures were evaluated at time points,...