Primary dysmenorrhea (PDM), the most prevalent menstrual cycle-related problem in women of reproductive age, is associated with negative moods. Whether pain and moods have a genetic basis remains unknown. Brain-derived neurotrophic factor (BDNF) plays key role production central sensitization contributes to chronic conditions. BDNF has also been implicated stress-related mood disorders. We screened genotyped Val66Met polymorphism (rs6265) 99 Taiwanese (Asian) PDMs (20–30 years old) 101...

Rutin and rutin-rich buckwheat are commonly used as alternative medicines due to their wide range of health benefits. The present study aims investigate anti-diabetes effects the association with glucagon-like peptide 1 (GLP-1) levels. A murine model type 2 diabetes (T2D), induced by a high-fat diet combined streptozocin injection, was utilized. T2D mice were fed 3% buckwheat, 10% or 0.1% rutin part for 4 weeks. Dipeptidyl peptidase-4 assays, secretin tumor cell line (STC-1) cells, GLP-1...

This study examines the associations among serum β2 microglobulin (B2M), malnutrition, inflammation, and atherosclerosis (MIA) in those with chronic kidney disease (CKD).CKD patients who were followed Taoyuan General Hospital from 2009 to 2015 enrolled. Demographic biochemical data, including B2M C-reactive protein (CRP) reviewed. The participants stratified according tertiles. Adjusted hazard ratios (AHRs) cumulative survival curves for death MIA syndrome evaluated by Cox model Kaplan-Meier...

Introduction Primary dysmenorrhea (PDM), the most prevalent gynecological problem among women of reproductive age, presents as a regular pattern cyclic menstrual pain. The presence or absence central sensitization (i.e., pain hypersensitivity) in cases PDM is contentious issue. Among Caucasians, associated with hypersensitivity throughout cycle, indicating amplification mediated by nervous system. We previously reported on to thermal Asian females. In this study, functional magnetic...

Objectives This retrospective study determines whether the kidney disease: improving global outcomes (KDIGO) criteria are superior to acute injury network (AKIN) in detecting non-dialysis AKI events and predicting mortality chronic disease (CKD) patients after surgery. Methods Surgical who were admitted intensive care unit enrolled. Non-dialysis cases defined using either KDIGO or AKIN creatinine stratified by CKD stages. The adjusted hazard ratios (AHRs) for in-hospital compared those...

Phytochemicals that interrupt adipocyte lifecycle can provide anti-obesity effects. 1,2,3,4,6-penta-O-galloyl-d-glucose (PGG) is a tannin with two isomers occurs widely in plants and exhibits various pharmacological activities. The aim of the investigation to comprehensively examine effects PGG isomer(s) on diet-induced obesity. Human mesenchymal stem cells (hMSC), 3T3-L1 fibroblasts, H4IIE hepatoma were used determine cell viability adipogenesis. Mice obesity generated from male C57/BL6...

Although hyperbaric oxygen therapy has not been accepted as a standard for traumatic brain injuries, it used, along with rehabilitative exercises, and the protocol low risk of complications. We report case chronic injury that progressed to tension pneumocephalus after therapy. The patient was 25-yr-old man who presented left occipital bone fracture subarachnoid subdural hemorrhage being hit by car. He underwent craniectomy remove hematoma cerebrospinal fluid diversion ventriculoperitoneal...

Objectives This study examines the associations between total testosterone levels and dialysis mortality. Methods Elderly men who initiate hemodialysis in Taoyuan General Hospital from January 2012 to June 2017 were enrolled. We reviewed clinical characteristics biochemical data start of followed over a 5‐year period after dialysis. Body composition parameters assessed 3‐6 months Skeletal muscle mass index ( SMMI ) was defined by skeletal divided squared height. those with lowest tertile...

Objectives Several factors in double filtration plasmapheresis (DFPP) were associated with triglyceride (TG) clearance rate. This study examines whether baseline whole blood viscosity was a predictor for efficient TG removal. Methods Adult subjects who receiving DFPP hyperlipidemia Taoyuan General Hospital from January 2015 to March 2018 classified into and inefficient removal according rate ≥50% vs <50%. defined as following formula: (pre‐apheresis TG‐ post‐apheresis TG)/pre‐apheresis...

Abstract Background/Aim To examine the association between body composition and dialysis mortality. Methods Adult patients who underwent haemodialysis in Taoyuan General Hospital from 2012 to 2016 were enrolled. We reviewed their baseline characteristics followed up treatment over 5 years after dialysis. Patients with mass index >25 kg/m 2 defined as obese. High or low muscle classified by skeletal ( SMMI ) based on consensus Chinese population. All age‐matched subjects into four groups:...

Objective To investigate the immediate effects of bilateral upper‐extremity sanding exercises on conduction and morphologic characteristics median ulnar nerves at wrist in hemiparetic subjects control subjects. Design Case study using a pretest–post‐test design. Setting Inpatient rehabilitation department affiliated with teaching hospital. Patients (or Participants) Thirty 21 matched who met our inclusion criteria had no history diseases that may have predisposed them to peripheral...

Mineral and bone disease (CKD-MBD), disorders of mineral metabolism, is associated with mortality cardiovascular in dialysis patients. However, the associations among time average values (P, Ca PTH) clinical outcomes are not well investigated. Objectives: This study examines from a single medical center. Methods: Adult patients who initiate hemodialysis Taoyuan General Hospital 2008 to 2013 were enrolled. We examined these using baseline time-average model. The included mortality, major...

Introduction The brain's reward system (RS) reacts differently to pain and its alleviation. This study examined the correlation between RS activity behavior during both painful pain-free periods in individuals with primary dysmenorrhea (PDM) elucidate their adaptive maladaptive responses throughout menstrual cycle. Methods Ninety-two PDM 90 control participants underwent resting-state functional magnetic resonance imaging (rsfMRI) scans peri-ovulatory phases. Regional homogeneity (ReHo)...

Primary dysmenorrhea (PDM) is a common condition among women of reproductive age, characterized by menstrual pain in the absence any organic causes. Previous research has established link between A118G polymorphism mu-opioid receptor (OPRM1) gene and experience PDM. Specifically, carriers G allele have been found to exhibit maladaptive functional connectivity descending modulatory system motor young with This study aims explore potential relationship OPRM1 changes white matter PDM.The...

The recognition of a closed spinal dysraphism without subcutaneous mass and cutaneous stigmata depends on the development relevant neurological urological symptoms signs. It can also be an incidental finding when that do not originate from it are investigated. We describe 39-year-old man who presented with spondylolysis-related low back pain. Plain film showed posterior spina bifida S1 magnetic resonance imaging L-spine revealed one intradural lipoma at L5 level cord tethering. Conservative...

The aim of this study was to investigate the immediate effects upper extremity loading exercises on conduction in median and ulnar nerves wrists hemiplegic patients. Seventeen patients without past history carpal tunnel syndrome or other confounding diseases seventeen healthy physically-matched control subjects were recruited. Nerve tests performed both arms controls before after a set 30-minute bilateral exercise. Significant reductions (p＜0.05) found compound motor action potential,...

BACKGROUND: This study examines the associations between low muscle mass, with or without overweight, and dialysis mortality. METHODS: Older patients who initiate hemodialysis in Taoyuan General Hospital from January 2012 to October 2016 were enrolled. We reviewed clinical characteristics, biochemical data at start of followed over a 4-year period after dialysis. Body composition parameters assessed 6 months 1 year Patients body mass index ＞ 25 kg/m^2 was defined as overweight. Lean tissue...

BACKGROUND: Obese paradox had been known in those commencing dialysis. However, it was unclear whether abdominal obesity more predictive for dialysis mortality than general obesity. This study examines sarcopenic death METHODS: Elderly who initiated hemodialysis Taoyuan General Hospital from January 2012 to March 2017 were classified into optimal, obesity, sarcopenia, and as well sarcopenia by skeletal muscle mass index (SMMI), handgrip strength (HGS) waist circumference (WC) definition. Men...