In Brief Menstrual pain is the most prevalent gynecological complaint, and usually without organic cause (termed primary dysmenorrhea, PDM). The high comorbidity in later life of PDM with many functional disorders (associated central dysfunction inhibition, eg, fibromyalgia) suggests possible maladaptive functionality modulatory systems already occurred young women, making them vulnerable to disorders. Periaqueductal gray (PAG) matter functions as a critical hub neuraxis systems; therefore,...

Abstract Background The benefits of low-dose ketamine for patients with treatment-resistant depression (TRD) and prominent suicidal ideation require further investigation. effects treatment refractoriness, the duration current depressive episode, number prior antidepressant failures on efficacy also clarification. Methods We recruited 84 outpatients TRD ideation—defined as a score ≥4 item 10 Montgomery–Åsberg Depression Rating Scale (MADRS)—and randomized them into 2 groups to receive 0.5...

Abstract Primary dysmenorrhea (PDM) is the most prevalent gynecological problem. Many key brain systems are engaged in pain processing. In light of dynamic communication within and between (or networks) shaping experience behavior, intra-regional functional connectivity (FC) hub regions may be altered interactions terms inter-regional FCs among networks reorganized to cope with repeated stress menstrual PDM. Forty-six otherwise healthy PDM subjects 49 age-matched, female control were...

Abstract Introduction: Severe primary dysmenorrhea (PDM) is a distressing pain affecting 10% to 25% of menstruating women. Little known about the analgesic efficacy and neural mechanisms transcranial direct current stimulation (tDCS) at motor area (M1) for menstrual control. Objectives: We examined anodal tDCS over left M1 patients with severe PDM studied functional connectivity (FC) changes between periaqueductal gray matter (PAG) medial (MMA) elucidate possible central mechanisms. Methods:...

Abstract Primary dysmenorrhea (PDM), menstrual pain without an organic cause, is a prevailing problem in women of reproductive age. We previously reported alterations structure and functional connectivity (FC) the periaqueductal gray (PAG) PDM subjects. Given that brain derived neurotrophic factor (BDNF) acts as modulator within PAG BDNF Val66Met polymorphism contributes towards susceptibility to PDM, present study imaging genetics set out investigate influence of, firstly, single nucleotide...

Abstract Numerous studies have reported that long‐term musical training can affect brain functionality and induce structural alterations in the brain. Singing is a form of vocal expression with an unparalleled capacity for communicating emotion; however, there has been relatively little research on neuroplasticity at network level vocalists (i.e., noninstrumental musicians). Our objective this study was to elucidate changes neural architecture following arts. We employed framework based...

The mu-opioid receptor (OPRM1) A118G polymorphism underpins different pain sensitivity and opioid-analgesic outcome with unclear effect on the descending modulatory system (DPMS). Primary dysmenorrhea (PDM), most prevalent gynecological problem clear painful free conditions, serves as a good clinical model of spontaneous pain. objective this imaging genetics study was therefore to explore if differences in functional connectivity (FC) DPMS between OPRM1 polymorphisms could provide possible...

Introduction The main objective of this research is to explore the core cognitive mechanisms utilized by exceptionally skilled percussionists as they navigate complex rhythms. Our specific focus on understanding dynamic interactions among brain regions, respectively, related externally directed cognition (EDC), internally (IDC), and rhythm processing, defined neural correlates processing (NCRP). Methods involved 26 participants each in percussionist group (PG) control (CG), who underwent...

To explore effective schemes of reducing carbon emission at the city level, this study evaluate decoupling situation and driving forces industrial in a coastal Zhuhai, China. Macro micro analyses evolutions energy consumption, emission, added value were conducted from 2006 to 2016. Carbon was decomposed overall subdivided level by using logarithmic mean division index method (LMDI) method. Results showed that emerges sustainable increase tendency. Both consumption keeps continuous during...

Introduction Primary dysmenorrhea (PDM), the most prevalent gynecological problem among women of reproductive age, presents as a regular pattern cyclic menstrual pain. The presence or absence central sensitization (i.e., pain hypersensitivity) in cases PDM is contentious issue. Among Caucasians, associated with hypersensitivity throughout cycle, indicating amplification mediated by nervous system. We previously reported on to thermal Asian females. In this study, functional magnetic...

Abstract Background P rimary dysmenorrhoea ( PDM ) is inexorably common. women suffer from cramping pain in the lower abdomen that starts with menstruation and lasts for 24–72 h. Up to 90% of adolescent girls more than 50% menstruating worldwide report suffering it. Ten 20% describe their as severe distressing. However, nothing known regarding association possible brain anomalies or abnormalities. Methods High‐resolution T 1‐weighted anatomical magnetic resonance images MRI were acquired...

Primary dysmenorrhea (PDM), painful menstruation without organic causes, is the most prevalent gynecological problem in women of reproductive age. Dysmenorrhea later life often co-occurs with many chronic functional pain disorders, and disorders exhibit altered large-scale connectedness between distributed brain regions. It unknown whether young PDM females alterations global local connectivity properties networks. Fifty-seven otherwise healthy 62 age- education-matched control participated...

Guangdong Province is the first batch of national low carbon pilots China. Studying interrelationships economic growth, energy consumption, and emission, as well driving forces emission not only important for local mitigation strategy, but also experience which can be provided other regions. In this work, within province was calculated from 1995 to 2015. Co-relationships were analyzed during past two decades. addition, force investigated by applying LMDI method. Results show that growth in...

Primary dysmenorrhea (PDM) refers to menstrual pain of which the pathological cause(s) are unknown. This study examined associations among BDNF Val66Met polymorphisms, severity, and hippocampal volume young PDM subjects. We recruited 115 subjects, including severe cases (n = 66) moderate 44), 117 females (aged 20-30 years) as a control group (CON) for genotyping MRI examination. The assessment involved analysis at various anatomical resolutions, i.e., whole volume, subfields, voxel-based...

China is now in the process of building its national carbon emissions trading scheme (ETS). Data are foundation for design and operation an ETS. This paper presents a comparative analysis data requirements China's ETS construction existing ETS-related enterprises China. In doing so, it identifies underlying gap terms availability quality. Based on experiences international ETSs, at pilot levels China, we propose two short-term strategies four long-term solutions to meet challenges from...

Introduction This study aimed to examine the white matter characteristics of visual artists (VAs) in terms creativity and structural connectivity within cortical system. Methods Diffusion spectrum imaging was utilized changes system a group VAs ( n = 25) comparison healthy controls matched for age education 24). To assess integrity its relationship with creativity, we conducted comprehensive analysis using region-based track-specific tractographic examinations. Results Our uncovered that...

Introduction Dance education fosters embodied metacognition, enhancing student’s creativity. This study examines the crucial role of functional connectivity (FC) between neural correlates metacognition (NCM) and dance (NCD) as neurological foundation for dancers’ metacognition. The investigation also explores whether these consolidated FCs inform general creativity in dancers. Methods research involved 29 dancers 28 non-dancer controls. examined resting-state connections NCM through...

With pronounced differences in emission factors among vehicle types and marked spatiotemporal heterogeneity of fleet composition, extrapolating composition from insufficient sample hour periods road segments will introduce significant uncertainty calculating regional daily traffic emissions. We proposed a framework to manage urban emissions associated with the perspective sampling coverage. Initially, respective relationships temporal spatial coverages resulting uncertainties were...