- Parasitic infections in humans and animals
- Reproductive tract infections research
- Bee Products Chemical Analysis
- Parasitic Infections and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Legionella and Acanthamoeba research
- Research on Leishmaniasis Studies
- Insect and Pesticide Research
- Phytochemical compounds biological activities
- Forensic Entomology and Diptera Studies
- Essential Oils and Antimicrobial Activity
- Reproductive System and Pregnancy
- Toxoplasma gondii Research Studies
- Insect Pest Control Strategies
- Amoebic Infections and Treatments
- Vector-borne infectious diseases
- Nanoparticles: synthesis and applications
- Parasite Biology and Host Interactions
- Yersinia bacterium, plague, ectoparasites research
- Moringa oleifera research and applications
- Phytochemistry and biological activities of Ficus species
- Heme Oxygenase-1 and Carbon Monoxide
- Aluminum toxicity and tolerance in plants and animals
- Bird parasitology and diseases
- Animal Ecology and Behavior Studies
University of Tabriz
2016-2024
Gonabad University of Medical Sciences
2023
Tarbiat Modares University
2017
Bacterial resistance to multiple drugs has recently emerged as a serious health problem. Concomitantly, the characterization of new substances with potential antimicrobial activity been less frequent in drug development industry. The overexpression genes encoding efflux pumps that expel from intracellular environment, lowering these subinhibitory concentrations, are among mechanisms predisposing microorganisms high resistance.
Echinococcus granulosus is causative agent of cystic echinococcosis (CE), which has a cosmopolitan distribution. The current methods for the treatment human CE include surgery. Therefore, development new scolicidal agents with low side effects and more efficacies an urgent need.The present study aimed to compare silver, iron, copper, silica zinc oxide nanoparticles (NPs) against hydatid cyst protoscolices in vitro.Hydatid cysts sheep liver lung were collected. fluid containing was aspirated...
Abstract Acanthamoeba spp. can cause amoebic keratitis (AK). Chlorhexidine is effective for AK treatment as monotherapy, but with a relative failure on drug bioavailability in the deep corneal stroma. The combination of chlorhexidine and propamidine isethionate recommended current treatment. However, effectiveness depends parasite virulence strains. This study aims to determine potential Garcinia mangostana pericarp extract α-mangostin against triangularis , well infection. minimal...
Trichomonas vaginalis, a parasitic flagellated protozoan, is one of the main non-viral sexually transmitted diseases worldwide. Treatment options for trichomoniasis are limited to nitroimidazole compounds. However, resistance these drugs has been reported, which requires development new anti-Trichomonas agents that confer suitable efficacy and less toxicity.In present work, we assessed effectiveness liposomal system containing essential oils Bunium persicum Trachyspermum ammi against T....
Abstract Background The larval stage of the tapeworm Echinococcus granulosus is causative agent hydatid disease in humans. This zoonotic parasitic infection remains a major health problem certain areas world where still endemic. In view ineffectiveness some drug treatments, surgical removal cysts preferred treatment option together with administration albendazole and mebendazole. However, severe side effects these drugs have been reported which demands developing new scolicidal agents that...
Curcuma longa (C. longa) rhizome extract has been traditionally used to treat many infections. Curcumin, a pure compound isolated from the plant, documented possess wide spectrum of pharmacological effects. The present study aimed investigate effects Thai medicinal plant extracts including C. and Curcumin on Acanthamoeba triangularis, causative agent human keratitis. parasite was recreational reservoir at Walailak University, Thailand. organism identified as A. triangularis using morphology...
The increasing rates of antimicrobial resistance have demanded the development new drugs as conventional antibiotics become significantly less effective. Evidence has identified a variety phytocompounds with potential to be used in combat infections caused by multidrug-resistant (MDR) bacteria. Considering verification that terpenes are promising antibacterial compounds, present research aimed evaluate and antibiotic-modulating activity (+)-α-pinene (-)-borneol against MDR bacterial strains....
, a well-known medicinal plant, has been used for several therapeutic purposes as it contains numerous pharmacological active compounds. Our study reported an anti-parasitic activity of
The aims of this study to assess the efficiency AGL against acetaminophen (APAP)-induced hepatic toxicity that was generated by mitochondrial oxidative stress and glutathione depletion. Free radical scavenging potentiality analyzed using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), hydrogen peroxide, nitric oxide, hydroxyl assays. APAP-induced liver formed at a dose level 640 mg/kg BW each, p.o. for 14 days all experimental rats except vehicle control group. (5 10 mg/kg) were treated orally with...
Plants with medicinal properties have been used in the treatment of several infectious diseases, including Acanthamoeba infections. The Cambodian plant extracts; Annona muricata and Combretum trifoliatum were investigated against triangularis. A total 39 extracts evaluated and, as a result, 22 showed positive anti-Acanthamoeba activity. Of extracts, 9 4 activity trophozoites cysts A. triangularis, respectively. minimum inhibitory concentration C. was 500 1,000 μg/mL, combination at 1/4×MIC...
Echinococcus granulosus is a zoonotic parasite causing hydatidosis in humans and animals. This study has been done order to investigate the effect of albendazole nanocrystals on viability E. protoscolices. The average size hydrodynamic diameter were 976±218 1334±502 nm, respectively. Fertile hydatid cysts isolated from liver slaughtered sheep. further identified using morphological molecular techniques. nucleotide sequence analysis indicated that genotype protoscolices was sensu stricto with...
<ns3:p><ns3:bold>Background</ns3:bold><ns3:bold>:</ns3:bold> Propolis is a natural resinous mixture produced by bees. It provides beneficial effects on human health in the treatment/management of many diseases. The present study was performed to demonstrate anti-<ns3:italic>Acanthamoeba</ns3:italic> activity ethanolic extracts samples from Iran. interactions compounds and essential proteins <ns3:italic>Acanthamoeba</ns3:italic> were also visualized through docking simulation.</ns3:p><ns3:p>...