A5002590126- Legionella and Acanthamoeba research
- Parasitic Infections and Diagnostics
- Essential Oils and Antimicrobial Activity
- Amoebic Infections and Treatments
- Parasites and Host Interactions
- Tuberculosis Research and Epidemiology
- Bacterial biofilms and quorum sensing
- Heme Oxygenase-1 and Carbon Monoxide
- Parasite Biology and Host Interactions
- Diagnosis and treatment of tuberculosis
- Malaria Research and Control
- Mosquito-borne diseases and control
- Toxoplasma gondii Research Studies
- Antibiotic Resistance in Bacteria
- Phytochemical compounds biological activities
- Bee Products Chemical Analysis
- Vibrio bacteria research studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Reproductive System and Pregnancy
- Research on Leishmaniasis Studies
- Computational Drug Discovery Methods
- Pharmacological Effects of Natural Compounds
- Ethnobotanical and Medicinal Plants Studies
- Probiotics and Fermented Foods
- Reproductive tract infections research
Walailak University
2017-2025
Universiti of Malaysia Sabah
2025
Center for Innovation
2022
University of Malaya
2005-2018
Prince of Songkla University
2017
University Malaya Medical Centre
2003-2006
Garcinia mangostana extract (GME) has severe pharmacokinetic deficiencies and is made up of a variety bioactive components.
The focus of this roadmap is to evaluate the possible efficacy
The occurrence of waterborne parasites coupled with water parameters at various processing sites two drinking treatment plants (A and B) seven distribution system (DS) in Sarawak, Malaysia were studied. Ten liters underwent immunomagnetic separation (IMS) technique to detect the presence Giardia Cryptosporidium (oo)cysts. remaining supernatant was used other whilst 50 mL sample each detection free-living amoebae fecal coliforms. Sampled positive for (32.9%; 28/85), (18.8%; 16/85) followed by...
Access to clean and safe drinking water that is free from pathogenic protozoan parasites, especially Cryptosporidium parvum Giardia lamblia cause gastrointestinal illness in humans, still an issue Southeast Asia (SEA). This study the first attempt detect aforementioned parasites samples countries SEA, using real-time polymerase chain reaction (qPCR) assays.A total of 221 10 l each were collected between April October 2013 Malaysia (53), Thailand (120), Philippines (33), Vietnam (15). A...
The resistance of bacteria to antibiotics is raising serious concern globally. Asian medicinal plants could improve the current treatment strategies for bacterial infections. antibacterial properties used by Khyang tribe in Bangladesh have not been investigated.The present study examines 18 day-to-day practice against human pathogenic bacteria.Leaves, bark, fruits, seeds, roots and rhizomes from collected were successively extracted with hexane, ethyl acetate ethanol. corresponding 54...
Abstract Acanthamoeba , a genus that contains at least 24 species of free-living protozoa, is ubiquitous in nature. Successful treatment infections always very difficult and not effective. More effective drugs must be developed, medicinal plants may have pivotal part the future drug discovery. Our research focused on investigating vitro anti- acanthamoebic potential Leea indica its constituent gallic acid different concentrations. Water butanol fractions exhibited significant amoebicidal...
Abstract Acanthamoeba spp. can cause amoebic keratitis (AK). Chlorhexidine is effective for AK treatment as monotherapy, but with a relative failure on drug bioavailability in the deep corneal stroma. The combination of chlorhexidine and propamidine isethionate recommended current treatment. However, effectiveness depends parasite virulence strains. This study aims to determine potential Garcinia mangostana pericarp extract α-mangostin against triangularis , well infection. minimal...
Significance This review discusses the coronavirus disease 2019 (COVID-19) pathophysiology in context of diabetes and intracellular reactions by COVID-19, including mitochondrial oxidative stress storms, ROS long COVID. Recent advances The COVID is suffered ~10% COVID-19 patients. Even virus does not exist, patients suffer for even over a year, could be mitochondria dysregulation disease. Critical issues Patients who recover from can develop new or persistent symptoms multi-organ...
Abstract There have been significant developments in the use of siRNA silencing cancer-allied target proteins with substantial apoptotic effects. Nevertheless, challenges regarding delivery for cancer therapy remain a major concern taking these therapies successfully from laboratory to vivo studies. Biomaterials are defined traditionally as any material that is used either medical or dental applications contact host cells form, such drug carrier device, prosthesis towards replacement damaged...
Acanthamoeba spp. are pathogenic microorganisms linked to severe infections in humans and animals, requiring a deeper understanding of their encystation process for effective diagnostics research. This study focused on developing novel encystment medium induce synchronized efficiently rapidly. The employed response surface methodology with central composite design optimize the formulation. key components included Tris-HCl, NaCl, glucose, MgCl2. optimized liquid was spray-dried produce...
Medicinal plants have been used as alternative agents for the treatment of infections. This study aimed to investigate bioactivities medicinal plant extracts including Knema retusa extract (Kre) against Acanthamoeba triangularis T4 in vitro and silico . Anti‐ activities 44 from 5 species were determined. From tested extracts, a chloroform Kre bark showed strongest anti‐ both trophozoites cysts, with MIC values 32.25 62.50 μg/mL, respectively. Then, amebicidal antiadhesion A. investigated....