Ibuprofen was the first member of Propionic acid derivatives introduced in 1969. It is a popular domestic and over counter analgesic antipyretic for adults children. has been rated as safest conventional NSAID by spontaneous adverse drug reaction reporting systems UK. This article summarizes main pharmacological effects, therapeutical applications reactions, drug-drug interactions food ibuprofen that have reported especially during last 10 years.

The effect of drug on a person may be different than expected because that interacts with another the is taking (drug-drug interaction), food, beverages, dietary supplements consuming (drug-nutrient/food interaction) or disease has (drug-disease interaction). A interaction situation in which substance affects activity drug, i.e. effects are increased decreased, they produce new neither produces its own. These interactions occur out accidental misuse due to lack knowledge about active...

Background: This study aimed to assess the knowledge, perception, and willingness of Saudi population towards stem cell treatment banking, associated factors, their predictive abilities. Methods: A cross-sectional was conducted from September December 2022 in Arabia using a structured bilingual, self-administered online survey collect sociodemographic information determine knowledge understanding, general population. Bloom’s cut-off points were used distribute scores into three categories,...

Acid suppressant medications, widely used to manage gastric acid secretions and related disorders, rely heavily on the expertise of community pharmacists. This underscores importance understanding pharmacists’ knowledge, attitudes, practices regarding counseling acid-suppressant medications. A cross-sectional survey-based study was conducted from end 23 rd August 2024 beginning 30 th September 2024. showed that most participants, 146 (64.6%), were females. 119 (52.65%), participants have...

system the clinical isolates were developing resistance to different antibiotics.According Technical Report by United States Agency for International Development, Ministry of Science and Technology, Government Pakistan Higher Education Commission, tedious problem antimicrobial needs develop resources address issue.This study aims define contemporary susceptibility patterns gram positive negative bacteria towards ceftriaxone.This also gives an insight pattern in ceftriaxone sensitive will...

Drug use has been identified as a major public issue in Pakistan. A descriptive questionnaire survey Karachi city was made to identify the socioeconomic profile and beliefs practices of 500 drug users The most commonly used drugs were cocaine (19.0%) crack-cocaine (15.0%), followed by amphetamine, (11.0%), alcohol, caffeine, barbiturates benzodiazepines (10.0% each). Key psychological factors leading tc problems with parental or marital relations break-up relationship (45.0%). Drugs seer an...

Objectives: This study was planned to determine the extent which role of a pharmacists is established in community pharmacies Pakistan and need qualified experienced provision healthcare at these medical stores or so called pharmacies. Materials Methods: A structured questionnaire distributed random sample 175 attendants various located different areas Karachi with response rate 90.28%. Questionnaire consisted 24 closed ended questions whose consistency reliability were determined by...

It constitutes a substantial proportion of the global burden disease. Major depressive disorder (MDD) was identified by World Health Organization (WHO) in 2001 as fourth leading cause disability and premature death world. is estimated that year 2020 MDD would be second to ischemic heart disease regard burden.

Ibuprofen is a propionic acid derivative that belongs to the class NSAIDs. Major adverse reactions associated with are related GIT and include peptic mucosal ulcers, dyspepsia, severe gastric pain bleeding, results in excessive treatment failure. The goal of this study was develop enteric coated ibuprofen tablets order avoid irritation, diffusion drug across lining let active ingredient be absorbed easily small intestine. formulation developed manufactured through direct compression process,...

This is the first article of its type to describe advances taking place in clinical pharmacy education Pakistan. The Pharmacy Council Pakistan has developed a five-year Pharm.D program replace four-year B.Pharm degree. Completing clerkships prerequisite for receiving To meet this requirement, Ziauddin College specialized clerkship 4th and 5th year students. fortunate be linked with well tertiary care hospitals at three prime locations metropolitan city Karachi, which provides opportunity...

To use Participatory Action Research (PAR) methodology to develop a competency-based training (CBT) program for Bachelor of Pharmacy interns at Mohammed Al-Mana College Medical Sciences (MACHS), Dammam, Saudi Arabia, based on the International Pharmaceutical Federation (FIP) Global Competency Framework. The MACHS Department Training Unit developed framework over 6 cohorts FIP Framework using methodology. Assignments were set throughout period support competency development. Assessment...

Many studies across the globe have observed significant effect of sleep disturbance on academic achievement medical students. Objective: This research was conducted to define prevalence and discover consequences management this condition among undergraduate pharmacy students Mohammed Al-Mana College for Medical Sciences (MACHS).

This study aimed to develop a stable and scalable enteric film-coated tablet for the gastric irritant dexibuprofen.

Sodium glucose co-transporters are a novel and potent class of anti-diabetic drugs. One the members this newest drugs is empagliflozin. It considered as favorable option for controlling type II diabetes mellitus. The objective current study based on quality surveillance different empagliflozin brands in Pakistan. Six counterparts (Emp-A to Emp-F) were collected assessed various pharmacopeial non-pharmacopeial tests. findings indicated good-quality features. In vitro kinetics was also...

Tobacco represents the single most preventable cause of disease and death in world today. There were approximately three million deaths annually at end 20th century it has been estimated that number will rise to more than 10 by 2030. 1 Globally, 47% males 12% females are smokers. In developing countries, 48% 7% smoke. Whereas developed 42% 24% 2 Kuznar et al. believed anti-tobacco prevention should be started very early before age continued up 21. Special attention taken 18 years as this...

This study was conducted to determine the various socio-demographic, economic, and clinical variables (SDECVs) which influence health-related quality of life (HRQoL) hypertensive patients. Three hundred fifty patients participated in this through a structured questionnaire EQ 5D 5L. 211(60.28%) participants had stage 1, 139 (39.7%) 2 hypertension. No reported severe problems any domain on Generalize Linear Model (GLM) used assess association between HRQoL SDECVs. The mean utility VAS score...