A5029190746- Analytical Methods in Pharmaceuticals
- Drug Solubulity and Delivery Systems
- Inflammatory mediators and NSAID effects
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical studies and practices
- Essential Oils and Antimicrobial Activity
- Plant tissue culture and regeneration
- Nanoparticles: synthesis and applications
- Advanced Drug Delivery Systems
- Computational Drug Discovery Methods
- Antibiotics Pharmacokinetics and Efficacy
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- Pharmacovigilance and Adverse Drug Reactions
- Phytochemicals and Medicinal Plants
- Environmental Toxicology and Ecotoxicology
- COVID-19 and Mental Health
- Pharmaceutical Economics and Policy
- Analytical Chemistry and Chromatography
- Anesthesia and Pain Management
- Ethnobotanical and Medicinal Plants Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Food Science and Nutritional Studies
- Natural Antidiabetic Agents Studies
- Crystallization and Solubility Studies
National University
2025
Jinnah Sindh Medical University
2016-2024
Sechenov University
2024
Maulana Azad National Institute of Technology
2013-2024
Riphah International University
2023
Quaid-i-Azam University
2020-2022
National University of Modern Languages
2022
Bahauddin Zakariya University
2022
University of the Punjab
2021
Jiangxi University of Science and Technology
2021
Isolation and evaluation of anticancer efficacy stigmasterol in a mouse model DMBA-induced skin carcinoma Huma Ali,1 Savita Dixit,1 Daoud Ali,2 Saeed M Alqahtani,3 Saad Alkahtani,2 Saud Alarifi2 1Department Chemistry, Maulana Azad National Institute Technology, Bhopal, India; 2Department Zoology, College Science, King University, Riyadh, Saudi Arabia; 3King Abdulaziz City for Science Arabia Abstract: Stigmasterol (99.9% pure) was isolated from Azadirachta indica its chemopreventive effect on...
Abstract: Gadolinium oxide (Gd 2 O 3 ) nanoparticles (GNPs) are applied in industrial products, for example, additives, optical glass, and catalysis. There various suggestions of metal paradigm but the underlying basic mechanism about toxicity nanoparticles, example GNPs, remains unclear. This experiment was done to measure effective GNPs (10, 25, 50, 100 µg/mL) over 24 48 h evaluate human neuronal (SH-SY5Y) cells. produced reactive oxygen species (ROS), as evaluated by 2',...
Abstract Microbial mediated synthesis of metallic nanoparticles constitutes as effective and promising approach for the development antibacterial materials in field bioengineering biomedicine. We prepared Cadmium oxide nanoaprticles (CdO NPs) utilizing Penicillium oxalicum , cadmium acetate solution via coprecipitate method. The elemental composition morphology these synthesized CdO NPs were examined through X‐ray diffraction (XRD), UV–Vis absorption spectroscopy, Fourier transform infrared...
To evaluate the antibacterial activity of flavanoids, Orientin and Vicenin, obtained from leaves Ocimum sanctum, have also been compared by their combine sample. Aqueous extract fresh sanctum was assessed for isolation purification different flavanoids. The Orientin, Vicenin Combine sample both these flavanoids evaluated according to well diffusion method against some bacteria causing Urinary Tract Infection (UTI) in human. result indicated that combined or synergistic individual showed...
To optimize the conditions for extraction of alkaloid palmatine from Tinospora cordifolia by using response surface methodology (RSM) and study its anticancerous property against 7,12-dimethylbenz(a)anthracene (DMBA) induced skin carcinogenesis in Swiss albino mice.
The communication between a substance and cell may depend on whether the is normal or pathological. disease cells drug interaction occasionally overcome beneficial action of drug; subsequently, it important to investigate effect in both target cells. This study aimed evaluate methotrexate (MTX) antiproliferative explore mechanistic approach death index SKOV-3 ovarian during treatment with MTX.In vitro studies were examined by tetrazolium assay after exposure various concentrations MTX....
Linum usitatissimum commonly known as flax or linseed is an important medicinal plant, produces medicinally potent lignans, used in the treatment of several human diseases. Lignans limited production natural plants does not meet increasing market demand. This study was conducted to establish easy and rapid method for vitro micropropagation lignans antioxidant secondary metabolites linseed. The results indicated that hypocotyl explants under effects thidiazuron (TDZ: 0.5 mg/L) + kinetin (Kn:...
Preliminary aim of this research work focuses on testing the efficacy silver nanoparticles synthesised using water soluble polysaccharides extracted from seaweeds against pathogenic fish bacteria. The emergence various virulence pathogens during culturing period leads to mass mortality and influence loss aquaculture production. intervention nanotechnology in field improves growth immunity aquatic animals when part nanomaterials mixed with feed. Sometimes green synthesis prepared seaweed...
In present report effects of explants type, basal media and plant growth regulators (PGRs) were tested for induction indirect somatic embryogenesis in medicinally important Silybum marianum L. Leaf, petiole root exploited vitro on B5 (Gamborg), SH (Schenk Hildebrandt) MS (Murashige Skoog) embryogenic callus followed by embryogenesis. Highest frequency (76 ± 4.8 %) was recorded when derived plantlets cultured medium supplemented with 1.5 mg l-1 2,4-dichlorophenoxyacetic acid (2,4_D)...
Drug use has been identified as a major public issue in Pakistan. A descriptive questionnaire survey Karachi city was made to identify the socioeconomic profile and beliefs practices of 500 drug users The most commonly used drugs were cocaine (19.0%) crack-cocaine (15.0%), followed by amphetamine, (11.0%), alcohol, caffeine, barbiturates benzodiazepines (10.0% each). Key psychological factors leading tc problems with parental or marital relations break-up relationship (45.0%). Drugs seer an...
ABSTRACT Mammalian studies have raised concerns about the toxicity of carbon nanotubes, but there is very limited data on ecogenotoxicity to aquatic organisms. The aim this study was determine eco‐geno toxic effects single walled nanotubes (SWCNTs) in fresh water snail, Lymnea luteola ( L. ). A static test system used expose a freshwater control, 0.05, 0.15, 0.30, 0.46 mg/L SWCNTs for up 4 days. changed significant reduction glutathione, glutathione‐ S ‐transferase, and glutathione...
The present investigation was carried out to examine the cytotoxic and genotoxic effects of a Tinospora cordifolia crude methanolic extract (palmatine) on human skin epithelial carcinoma cells (A431). T. is one indispensable medicinal plants used in Ayurvedic medicine for treatment various diseases recommended improving immune system. Cytotoxicity genotoxicity evaluation using A431 treated with different concentrations palmatine. duration 24 48 hr. A cellular proliferative capacity test...
The current study was aimed to enzymatically modify maize flour by using amylase and pullulanase in combination for increasing the yield of resistant starch type III (EM-RSIII). enzymatic treatment imparts unique desired physicochemical properties including content, amylose milk, oil, water interaction ability. sensory analysis performed distributing questioners among individual results were interpreted 5-point hedonic scale. Result indicated an increase stability, milk absorption capacity...
Abstract: Quercetol is a polyphenolic molecule present in vegetables and fruits, beneficial to human animal health. The current work aimed test cytotoxic apoptotic effects of quercetol on HepG2 cells. was isolated from Ocimum sanctum characterized by gas chromatography–tandom mass spectrometry (GC-MS/MS), nuclear magnetic resonance spectroscopy, Fourier transform infrared spectroscopy. (50–600 µg/mL) examined for activity tetrazolium salt neutral red uptake tests comet assay genotoxicity,...