A5047881757- Sperm and Testicular Function
- Hormonal and reproductive studies
- Mesenchymal stem cell research
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Regulation of Appetite and Obesity
- Nerve injury and regeneration
- Ovarian function and disorders
- Biochemical Analysis and Sensing Techniques
- Acute Kidney Injury Research
- Endometriosis Research and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Reproductive System and Pregnancy
- Surgical Sutures and Adhesives
- Garlic and Onion Studies
- Genital Health and Disease
- Liver physiology and pathology
- Neurogenesis and neuroplasticity mechanisms
- Intraocular Surgery and Lenses
- Chemotherapy-induced organ toxicity mitigation
- Environmental Science and Water Management
- Pharmacological Effects of Natural Compounds
- Chronic Kidney Disease and Diabetes
- Drug Transport and Resistance Mechanisms
- Effects and risks of endocrine disrupting chemicals
Assiut University
2012-2023
Stomatology Hospital
2015
In a prospective experimental study, the effects of chronic tramadol administration on gonadotrophic and sex hormones, histopathological morphometrical alterations in rat testicular tissue were investigated laboratory setting. Tramadol was given alone to adult male albino rats. Gonadotrophic serum hormone levels measured pathological morphometric changes observed treated vs.After 30 days treatment, induced decrease LH, FSH testosterone levels. Histologically, degenerative seminiferous...
Few data are available about the role of herbal extract loaded nanoparticles as an alternative safe medicine for management a gastric ulcer.This work is targeted at exploring physiological effects pomegranate (PLN) against indomethacin IND-induced ulcer and comparing results with traditional peel (PPE).Twenty-four rats were equally distributed into four groups: control, IND-treated, PLN-treated, PPE-treated groups. Gross examination mucosa, calculation inhibition indices done. Serum...
Reproductive dysfunction is a common consequence of both obesity and diabetes. This study investigated the impact diabetes, alone or combined, on physiological reproductive parameters in male rats. Twenty-four Wistar Albino rats were divided into four groups: Control; obese non-diabetic; diabetic; diabetic. Obesity was provoked by consumption high-fat diet (HFD) consisting 40% energy from fat for 90 days. Diabetes induced an intraperitoneal injection streptozotocin at dose 40 mg/kg/day three...
Telocytes are specialized interstitial tissue cell type. Our aim is to characterize telocytes in human uterine leiomyoma (ULM) and its adjacent myometrium (Myo-F) as well normal (Myo-N).ULMs Myo-F tissues were taken from hysterectomy specimens done treat symptomatic fibroids (N = 20). Myo-N isolated hysterectomies on ULM- free uteri for other benign indications 15).Telocytes detected using immunohistochemistry detect c-Kit (CD-117), a surface marker expressed telocytes, electron microscopic...
Endometriosis is a chronic debilitating inflammatory condition characterized by the presence of endometrial tissues outside uterine cavity. Pelvic soreness and infertility are usual association. Due to poor effectiveness hormone therapy high incidence recurrence following surgical excision, there no single effective option for management endometriosis. Mesenchymal stem cells (MSCs) multipotent stromal studied their broad immunoregulatory anti-inflammatory properties; however, efficiency in...
The study aimed to compare the histological features of Leydig cells and macrophages in testicular interstitium obstructive versus nonobstructive azoospermia. Thirty-nine azoospermic men undergoing sperm extraction during intracytoplasmic injection were allocated into azoospermia group (GI) (GII) which was subdivided Sertoli cell-only syndrome (GIIA), germ cell arrest (GIIB) hypospermatogenesis (GIIC) subgroups. Serum LH, FSH testosterone levels measured. Ultrastructural changes mean number...
To evaluate light and electron microscopic changes of the anterior capsule its epithelium after clear lens extraction vitrectomized myopic eyes with silicone oil tamponade.This prospective, controlled, non-randomized, interventional study included 20 capsular specimens that were excised during combined removal from previously highly patients tamponade for previous retinal detachment surgeries. The examined via microscopy compared removed non-vitrectomized eyes.Light examination filled showed...
Numerous experimental studies have shown various pharmacological activities including geraniol's cancer prevention agent and antioxidant capacity. The goal of this investigation is to mark the prospective defensive role geraniol in rat's carbon tetrachloride (CCl4) instigated liver fibrosis.Liver fibrosis was prompted by subcutaneous injections CCl4, twice week for about a month. Simultaneously, (200 mg kg-1) orally regulated every day. Post-Hoc-Test were carried out where p<0.05 has been...
Background and aim Low-level laser irradiation (LLLI) has been shown to modulate the proliferation of endothelial cells. Helium–neon (He–Ne) is best type for biostimulation. The present study was investigate direct stimulatory effect LLLI on proliferative potential human umbilical vein cell line in vitro. Materials methods This included five groups: group I (zero time after seeding He–Ne irradiation), II (24▒h III (48▒h IV (96▒h V (cumulative every 48▒h a period 6 days). Each subdivided into...
Rheumatoid arthritis (RA) is one of the most widespread autoimmune disorders and it has a genetic background with variety genes affecting degradation immune system. Along these lines, we assessed relationship between BsmI, FokI VDR polymorphisms inflammable records identified infections activity. Such as interleukins (IL-6, IL-8), hypoxia inducible factor-alpha (HIF-α), soluble receptor advanced glycation end product (sRAGE), oxidized low-density lipoprotein cholesterol (oxLDL), neutrophil...
Background Normal human skin has the ability to stretch and return its shape without becoming damaged. Many conditions involving such as fluctuations in body weight or repeated pregnancy might induce histological alterations. Objective The aim of this work was study stretch-induced morphological changes that occur because adult women. Participants methods Fifteen biopsies were taken from lower anterior abdominal wall Egyptian women after obtaining written consent. They divided into three...
Background Epidermal growth factor (EGF) is produced in rodents mainly by the granular convoluted tubules submandibular glands. EGF deficiency diabetes mellitus could be implicated complications of disease. Sildenafil (Viagra), one phosphodiesterase inhibitors, contributes protection against diabetes-induced oxidative stress. Aim study To investigate effect sildenafil on level production gland diabetic male rats, and expression its receptors surface target cells as testis. Materials methods...
Background Age-related sarcopenia represents a powerful risk factor for the loss of independence and physical disability in elderly. Green tea contains series polyphenols called catechins has been applied disease prevention treatment. Aim study To determine effects intake green on age-related changes skeletal muscle. Materials methods Thirty female albino rats were divided into three equal groups: group I (control adults) included 6-month-old rats, II (aged) 18-month-old III (green treated)...
Background: Synovial membrane represents a worthy source of mesenchymal stem cells (MSCs).Synovial derived has been described as encouraging line treatment for musculoskeletal degenratative disorders compared to other sources MSCs.Having higher chondrogenic capacity and being easy collect without injury adjacent tissue well its proximity the articular cartilage make it good choice such disorders. Aim work:The present study aimed isolate characterize (MSCs) from synovial examine myogenic...
Abstract Introduction/Objective Acute kidney injury (AKI) causes significant morbidity and mortality and, if left unmanaged, can progress to chronic disease. Despite the advances in our understanding of pathogenesis AKI, there are no available therapeutics combat it effectively. Folic acid (FA)-induced AKI is a well established rat model characterized by acute renal due disturbance antioxidant system with subsequent fibrosis. Morin hydrate, well-known bioactive flavonoid, has been proven...