A5075308079- Adsorption and biosorption for pollutant removal
- Medicinal Plants and Neuroprotection
- Natural Antidiabetic Agents Studies
- Nanoparticle-Based Drug Delivery
- Analytical chemistry methods development
- Aldose Reductase and Taurine
- Chromium effects and bioremediation
- Heavy metals in environment
- Layered Double Hydroxides Synthesis and Applications
- Complement system in diseases
- Phosphorus and nutrient management
- Immune Cell Function and Interaction
- Nanoplatforms for cancer theranostics
- Nanomaterials for catalytic reactions
- Pharmaceutical and Antibiotic Environmental Impacts
- Moringa oleifera research and applications
- Supramolecular Self-Assembly in Materials
- Phagocytosis and Immune Regulation
- Animal health and immunology
- Chemotherapy-induced cardiotoxicity and mitigation
- Diet, Metabolism, and Disease
- Arsenic contamination and mitigation
- Protein Interaction Studies and Fluorescence Analysis
- Animal Nutrition and Physiology
- Medicinal Plant Research
Newcastle University
2022-2024
Imam Abdulrahman Bin Faisal University
2023
University of Haripur
2017-2023
Hazara University
2023
M S Ramaiah University of Applied Sciences
2016-2022
Abbottabad University of Science and Technology
2020-2021
COMSATS University Islamabad
2013-2021
Bangabandhu Sheikh Mujib Medical University
2018
University of Chittagong
1998
The complement system, professional phagocytes and other cells such as Natural killer mast are among the important components of innate arm immune system. These constituents provide an orchestrated array defences responses against tissue injury foreign particles, including nanopharmaceuticals. While interception nanopharmaceuticals by system is beneficial for immunomodulation treatment phagocytic cell disorders, it imperative to understand multifaceted mechanisms which interacts with...
Waste wood biomass as precursor for manufacturing activated carbon (AC) can provide a solution to ever increasing global water quality concerns. In our current work, Melia azedarach derived phosphoric acid-treated AC (MA-AC400) was manufactured at laboratory scale. This novel MA-AC400 tested RO16 dye removal performance function of contact time, adsorbent dosage, pH, temperature and initial concentration in batch scale arrangement. characterized via scanning electron microscopy, energy...
Eucalyptus wood is made up of lignocellulosic material; this material contains two types biopolymers, i.e., carbohydrate and aromatic polymers. In study, was used to prepare biochar. Three biochar, laboratory-based (B1), barrel-based (B2), brick kiln-biochar (B3), were for fluoride arsenic removal from aqueous solution. Barrel-based biochar prepared by using the two-barrel method's alteration. The highest (99%) attained at pH 2 in presence B1, while B2 B3, maximum 90% 45.7%, respectively. At...
Background: Biodegradable poly(alkyl cyanoacrylate) (PACA) nanoparticles (NPs) are receiving increasing attention in anti-cancer nanomedicine development not only for targeted cancer chemotherapy, but also modulation of the tumor microenvironment. We previously reported promising results with cabazitaxel (CBZ) loaded poly(2-ethylbutyl NPs (PEBCA-CBZ NPs) a patient derived xenograft (PDX) model triple-negative breast cancer, and this was associated decrease M2 macrophages. The present study...
Abstract Cr(VI) adsorption was studied for abundantly available low-cost lignocellulosic adsorbents in Pakistan namely, tobacco stalks (TS), white cedar stem (WCS) and eucalyptus bark (EB). Several process variables like contact time, adsorbent dose, pH, metal concentration, particle size temperature were optimized batch mode. EB showed high of 63.66% followed by WCS 62% TS 57% at pH 2, which is higher than most the reported literature. Langmuir isotherm (R 2 = 0.999) well fitted into...
Abstract Development of diabetic cataract is mainly associated with the accumulation sorbitol via polyol pathway through action Aldose reductase (AR). Hence, AR inhibitors are considered as potential agents in management cataract. This study explored inhibition Hemidesmus indicus var. pubescens root extract by silico and ex vivo methods. Molecular docking studies (Auto Dock tool) between β-sitosterol, hemidesminine, hemidesmin-1, hemidesmin-2, showed that β-sitosterol (− 10.2 kcal/mol)...
The contribution of the complement system to non-specific host defence and maintenance homeostasis is well appreciated. Many particulate systems trigger activation but underlying mechanisms are still poorly understood. Activation cascade could lead particle opsonisation by cleavage products third protein might promote inflammatory reactions. Antibody binding in a controlled manner and/or sensing particles pattern-recognition molecules such as C1q mannose-binding lectin can activation....
A peptide-based hydrogel sequence was computationally predicted from the Ala-rich cross-linked domains of elastin. Three candidate peptides were subsequently synthesised and characterised as potential drug delivery vehicles. The elastin-derived are Fmoc-FFAAAAKAA-NH2, Fmoc-FFAAAKAA-NH2, Fmoc-FFAAAKAAA-NH2. All three peptide sequences able to self-assemble into nanofibers. However, only first two could form hydrogels, which preferred systems compared solutions. Both these also exhibited...
The complement system is a multicomponent and multifunctional arm of the innate immune system. Complement contributes to non-specific host defence maintains homeostasis through multifaceted processes pathways, including crosstalk with adaptive system, contact (coagulation) kinin systems, alarmin high-mobility group box 1. also present intracellularly, orchestrating wide range housekeeping physiological in both nonimmune cells, thus showing its more sophisticated roles beyond immunity, but...
Murva is an important drug in Ayurveda. Wattakaka volubilis used as one of the botanical sources Murva. The aim this study to evaluate effect alcohol extract W. root streptoztocin (STZ) induced diabetes and diabetic neuropathy. Diabetes mellitus (DM) was by administration STZ (45 mg/kg, i.p). DM within 72 h. Diabetic animals were treated with glimepiride (0.5 mg/kg) ethyl 100 200 mg/kg for 21 d. After determining changes fasting serum glucose lipid profile, further a period 15 d determine...
Tobacco stalk biomass (TSB) is explored for reactive black 5 (RB5) dye treatment in batch reactor.TSB displayed RB5 adsorption efficiency of 93.5% at 120 min.The data were fitted to linear and non-linear isotherms kinetic models.Error functions determined have a holistic view on optimum parameters validate prediction models.Harkin-Jura exhibited better fit than that Freundlich Langmuir suggesting multilayer onto TSB the basis R 2 chi-square (χ ) error values.Adsorption kinetics was best...
Abstract: Aim: The aim of this study was to investigate the aldose reductase inhibition and anti-cataract property W. volubilis root extract in rats with streptozotocin induced diabetes mellitus. Methods: Diabetes by a single intraperitoneal injection at dose 45 mg/kg. Diabetic animals were treated glimepiride (0.5 mg/kg) alcohol 100 200 mg/kg for 38 d. Lens isolated certain markers estimated. Results: Treatment diabetic inhibited activity (p < 0.001) sorbitol formation lens. Additionally,...
Tungsten (W) and Cerium (Ce) doped nanoTitanium oxide (TiO 2 ) nanophotocatalyst were prepared by the sol-gel method their photodegradation effect against atrazine herbicide investigated. The doping of nanocatalyst took place at 50 °C within a time interval 120 minutes. gel was dried calcined in oven 350 for 75 XRD result revealed that synthesized 16.7 nm size with mostly monoclinic structure. With FTIR spectra, characteristic peaks TiO found 516 cm -1 , Ti-O-Ce 1104 W-O single bond 1609 ....
Abstract In this study, the MgFeCa layered double hydroxides was supported in biochar (B) using co-precipitation, hydrothermal, and co-pyrolysis methods. The prepared B-MgFeCa composites were investigated for tetracycline (TC) adsorption from an aqueous solution. synthesized through co-precipitation hydrothermal methods exhibited better crystallinity, functional groups, well-developed LDH structure within matrix. However, method resulted breakage, leading to low crystalline composite...
Radiation doses of occupational personnel exposed from diagnostic x rays, therapeutic installations, and patients were measured using thermoluminescent dosimeters. The monthly ray ranged 0.1076 mSv to 0.5774 mSv, those treatment 0.365 0.657 which is within the dose limit recommended by ICRP 60. patient organ evaluated found range 0.0615 s(-1) 2.8823 for gonad, 0.3676 2.1088 thyroid, 0.00972 4.01 eyes.
Cardiovascular diseases (CVDs) are highly prevalent in various countries, and heart failure accounts for the majority of deaths. The present study focuses on determining protective effect ethanol extract leaves Tamarindus indica (TIEE) by vitro vivo methods.In cardiotonic activity was determined using Langendorff's perfusion assembly. In studies were performed Doxorubicin (1.5 mg/kg, i.p seven days) induced cardiotoxicity rats. These animals simultaneously treated with TIEE at a low dose...