- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Hemodynamic Monitoring and Therapy
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Syncope and Autonomic Disorders
- Hormonal Regulation and Hypertension
- Cardiovascular Function and Risk Factors
- Oral microbiology and periodontitis research
- Eicosanoids and Hypertension Pharmacology
- Aortic Disease and Treatment Approaches
- Cardiomyopathy and Myosin Studies
- Neuropeptides and Animal Physiology
- Renin-Angiotensin System Studies
- Neuroendocrine regulation and behavior
- Nitric Oxide and Endothelin Effects
- Connective tissue disorders research
- Health and Medical Studies
- Circadian rhythm and melatonin
- Cardiac Imaging and Diagnostics
- Neurofibromatosis and Schwannoma Cases
- Ultrasound and Hyperthermia Applications
- Cardiovascular Issues in Pregnancy
- Streptococcal Infections and Treatments
Orthopädische Praxis
2022-2024
Medical University of Graz
2017-2023
Universitätsklinik für Frauenheilkunde und Geburtshilfe
2020
University Hospital Schleswig-Holstein
2012-2017
University of Lübeck
2010-2017
Universitäres Kinderwunschzentrum Lübeck
2014-2017
Charité - Universitätsmedizin Berlin
2012
Comenius University Bratislava
2012
Williams & Associates
2012
Universitätsklinikum Würzburg
2011
In the European Society of Cardiology–European Hypertension guidelines year 2007, consequences arterial stiffness and wave reflection on cardiovascular mortality have a major role. But investigators claimed poor availability devices/methods providing easy widely suitable measuring wall or their surrogates like augmentation index (AIx) aortic systolic blood pressure (aSBP). The aim this study was validation novel method determining AIx aSBP based an oscillometric using common cuff (ARCSolver)...
Introduction Pulse wave velocity (PWV) and augmentation index (AIx) are parameters of arterial stiffness reflection. PWV AIx strong indicators for cardiovascular risk used increasingly in clinical practice. Previous systems assessment investigator dependent time consuming. The aim this study was to validate the new oscillometric method (Arteriograph) determining by comparing it two clinically validated, broadly accepted tonometric piezo-electronic (SphygmoCor Complior). Design were measured...
Arterial stiffness, as measured by arterial pulse wave velocity (PWV), is an established biomarker for cardiovascular risk and target-organ damage in individuals with hypertension. With the emergence of new devices assessing PWV, it has become evident that some these yield results display significant discrepancies compared previous devices. This discrepancy underscores importance comprehensive validation procedures need international recommendations.
Pulse wave velocity (PWV), a direct marker of arterial stiffness, is an independent cardiovascular risk factor. Although the angiotensin II type 1 receptor blockade belongs to major antihypertensive and cardioprotective therapies, less known about effects long-term stimulation 2 receptor. Previously, compound 21, selective nonpeptide agonist improved outcome myocardial infarction in rats along with anti-inflammatory properties. We investigated whether 21 alone or combination by olmesartan...
Objective Hypobaric hypoxia, physical and psychosocial stress may influence key cardiovascular parameters including blood pressure (BP) pulse (PP). We investigated the effects of mild hypobaric hypoxia exposure on BP PP reactivity to mental passive elevation by cable car. Methods 36 healthy volunteers participated in a defined test procedure consisting period rest 1, task (KLT-R), 2, combined (KLT-R) (bicycle ergometry) last both at Graz, Austria (353 m asl) top station Dachstein (2700 asl)....
Ninety-six persons, living in Gothenburg, Sweden, on the first of January 1978 and known by health services as cases neurofibromatosis, were investigated concerning clinical genetic aspects disease. Close relatives also interviewed examined. The diagnostic criteria operationally defined according to number café-au-lait spots and/or neurofibromas. prevalence neurofibromatosis was estimated be 0.02%. following findings made patients: axillary freckling (48%), neurological symptoms (30%),...
Noninvasive applanation tonometry (APT) is useful to assess aortic stiffness and pulse wave reflection. Moreover, APT can predict outcome in many conditions such as arterial hypertension. In this study, we test whether measurements relate progression of disease Marfan syndrome (MFS).We performed 50 consecutive, medically treated adults with MFS (19 men 31 women aged 32 +/- 13 years), who had not undergone previous cardiovascular surgery. During 22 16 months follow-up, 26 these patients...
Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study
Aim This single blind cross-sectional study compared the vascular health of subjects suffering from severe chronic periodontitis, aggressive periodontitis and periodontal healthy controls by evaluating pulse wave velocity (PWV), augmentation index (AIx) pressure amplification (PPA). Material Methods In a total 158 subjects, 92 66 matched controls, PWV, AIx, central peripheral blood were recorded using an oscillometric device (Arteriograph). Results Subjects or exhibited significantly higher...
Various statements are made concerning peaks of heart rate (HR), blood pressure (BP) and double product (product HR systolic BP) as triggers for ST-segment depression. The aim the present study was to identify determinants depression with a new ambulatory device simultaneous 24-h electrocardiogram (ECG) BP monitoring.A total 63 treated patients (63 +/- 9 years, 33 women 30 men) arterial hypertension ischemic disease were studied measurement (ABPM) evaluated according BHS protocol...
The augmentation index at a heart rate of 75 beats/min (AIx@HR75) and central pulse pressure (CPP) can be measured noninvasively with applanation tonometry (APT). In this observational study, we investigated the relationship between AIx@HR75, CPP aortic disease in patients Marfan-like syndromes.We performed APT 78 consecutive whom classic Marfan syndrome (MFS) had been excluded (46 men 32 women aged 34 +/- 13 years). These comprised 9 persons MFS-like habitus, 6 bicuspid valve (BAV), 5 MASS...
Abstract Aim This study assessed the impact of anti‐infective periodontal therapy on status vascular health. Materials and Methods Periodontal health 55 patients with severe untreated chronic periodontitis was evaluated before 12 months after therapy. Observed parameters were bleeding probing (BoP), pocket depth ( PPD ), inflamed surface area index PISA pulse wave velocity PWV augmentation AI x), central pressure PP ao) peripheral systolic RR sys). Results Δ (baseline‐12 months) correlated...
Background: Antares is an algorithm for pulse wave analysis (PWA) by oscillometric blood pressure (BP) monitors in order to estimate central (aortic) (cBP). aims enable brachial cuff-based BP be type II-devices, determining absolute cBP values independently of potential peripheral inaccuracies. The present study invasive validation the custo screen 400. Methods: We followed entirely 2017 ARTERY protocol non-invasive devices, 2013 American National Standards Institute, Inc./Association...
Antares is a pulse wave analysis (PWA) algorithm designed to allow non-invasive estimation of central (aortic) blood pressure (cBP) using automated oscillometric (BP) devices. Diabetes may affect elastic and muscular arteries differently, resulting in disparate characteristics peripheral arteries, which limit the accuracy PWA The aim our study was evaluate for estimating cBP as compared with invasively measured patients type 2 diabetes.In this study, consecutive undergoing elective coronary...
We have recently shown that mean pulse pressure is higher in patients with transient myocardial ischemia. Pulse elevation might be an important consequence of increased arterial stiffness. The aim this study was to prove if stiffness changed ischemia who bear a high cardiovascular risk. Additionally we investigated whether or wave reflection the best indicator for Aortic velocity (PWV) measure stiffness, and augmentation index (AIx) indication reflection. Both are indicators risk.PWV...
To test the ability of an established traditional cardiovascular (CV) risk prediction score [Systematic COronary Risk Evaluation (SCORE)] and its EULAR modified version (mSCORE) to identify antisynthetase syndrome (ASyS) patients at high CV examine for first time associations cerebrovascular surrogate markers with clinical immunological ASyS parameters.SCORE/mSCORE gold standard marker aortic stiffness [carotid-femoral pulse wave velocity (cfPWV)] were examined in healthy controls. Moreover,...