A5068499202- Paraoxonase enzyme and polymorphisms
- Apelin-related biomedical research
- Hormonal Regulation and Hypertension
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Heart Rate Variability and Autonomic Control
- Dialysis and Renal Disease Management
- Long-Term Effects of COVID-19
- Parkinson's Disease Mechanisms and Treatments
- Chronic Kidney Disease and Diabetes
- Acute Ischemic Stroke Management
- Vitamin C and Antioxidants Research
- High Altitude and Hypoxia
- Coenzyme Q10 studies and effects
- Circadian rhythm and melatonin
- Acute Kidney Injury Research
- Thermal Regulation in Medicine
- Peripheral Artery Disease Management
- Iron Metabolism and Disorders
- Antioxidant Activity and Oxidative Stress
- Trace Elements in Health
Universidade Estadual de Londrina
2012-2025
Weatherford College
2022
Chulalongkorn University
2022
King Chulalongkorn Memorial Hospital
2022
ORCID
2022
Entomological Society of Brazil
2022
There is evidence that immune-inflammatory, stress of reactive oxygen and nitrogen species (IO&NS) processes play a role in the neurodegenerative observed Parkinson's disease (PD). The aim present study was to investigate peripheral IO&NS biomarkers PD. We included 56 healthy individuals PD patients divided two groups: early stage late stage. Plasma lipid hydroperoxides (LOOH), malondialdehyde (MDA), nitric oxide metabolites (NOx), sulfhydryl (SH) groups, catalase (CAT) activity, superoxide...
Aims: This study investigated a) whether the affective, chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME), respiratory, and neurological Long COVID (LC) symptom domains are intercorrelated manifestations of an underlying construct, namely LC phenome; b) predictive effects clinical symptoms biomarkers COVID-19 infectious phase on LC. Methods: cohort included 71 patients who had suffered from six months prior. The complied with disease criteria set forth by World Health Organization...
Abstract Background Major depressive disorder (MDD) is associated with neuro-immune – metabolic oxidative (NIMETOX) pathways. Aims To examine the connections among NIMETOX pathways in outpatient MDD (OMDD) and without syndrome (MetS); to determine prevalence of aberrations a cohort OMDD patients. Methods We included 67 healthy controls 66 patients we assessed various Results successfully identified subgroup individuals pathways, including diminished lecithin-cholesterol acyltransferase...
Background: Parkinson's disease (PD) is a neurodegenerative disorder characterized by complex interplay between peripheral and central inflammatory oxidative stress pathways. Keywords: Inflammation, iron metabolism, stress, disease, Peripheral biomarkers, Systemic disease.
In acute ischemic stroke (AIS), there are no data on whether oxidative stress biomarkers have effects above and beyond known risk factors measurements of volume. This study was conducted in 122 mild-moderate AIS patients 40 controls assessed the modified ranking scale (mRS) at baseline, 3 6 months later. We measured lipid hydroperoxides (LOOH), malondialdehyde (MDA), advanced oxidation protein products, paraoxonase 1 (PON1) activities PON1 Q192R genotypes, high density lipoprotein...
Abstract Premature atherosclerosis represents the main cause of mortality among end‐stage renal disease patients ( ESRD ). Increased inflammation and oxidative stress are involved in initiation progression atherosclerotic plaque. As foam cells capable producing significant amounts inflammatory mediators free radicals, we hypothesized that from uremic could produce more than normal people be, somehow, accelerated uremia. To test this hypothesis, levels a few markers stress: Tumor necrosis...
Abstract Undergraduate students are frequently afflicted by major depressive disorder (MDD). Oxidative and nitrosative stress (O&NS) has been implicated in the pathophysiology of MDD. There is no information regarding whether mild outpatient MDD (SDMD) first episode SDMD (FE-SDMD) accompanied O&NS. The current study compared lipid hydroperoxides (LOOH), malondialdehyde (MDA), advanced protein oxidation products, nitric oxide metabolites (NOx), thiol groups, plasma total antioxidant...
Abstract Aims: This study aims to examine the associations between paraoxonase 1 (PON)1 status and acute ischemic stroke (AIS) consequent disabilities. Methods: recruited 122 patients with AIS 40 healthy controls assessed Q192R gene variants, arylesterase (AREase) chloromethyl phenylacetate (CMPAase) activities, high-density lipoprotein cholesterol (HDL) in baseline conditions. AREase CMPAase were measured 3 months later. The National Institutes of Health Stroke Scale (NIHSS) modified Rankin...
Abstract In acute ischemic stroke (AIS), there are no data on whether lipid and protein oxidation antioxidant biomarkers associated with the outcome of AIS above beyond effects traditional risk factors, immune metabolic biomarkers, measurements volume. The present study was conducted in 135 mild to moderate patients 40 controls assessed modified raking scale (mRS) at baseline, 3 6 month later. We measured hydroperoxides (LOOH), malondialdehyde (MDA), advanced products, paraoxonase 1 (PON1)...
Abstract Aims This study aims to examine the associations between paraoxonase 1 (PON)1 status and acute ischemic stroke (AIS) consequent disabilities. Methods recruited 122 patients with AIS 40 healthy controls assessed Q192R gene variants, arylesterase (AREase) chloromethyl phenylacetate (CMPAase) activities, high-density lipoprotein cholesterol (HDL) in baseline conditions. AREase CMPAase were measured 3 months later. The National Institutes of Health Stroke Scale (NIHSS) modified Rankin...