A5054260833- Parkinson's Disease Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Cerebral Palsy and Movement Disorders
- Neurological disorders and treatments
- Coenzyme Q10 studies and effects
- Vitamin C and Antioxidants Research
- Nuclear Receptors and Signaling
- Botulinum Toxin and Related Neurological Disorders
- Electrochemical sensors and biosensors
- Genetic Neurodegenerative Diseases
- Paraoxonase enzyme and polymorphisms
- Iron Metabolism and Disorders
- RNA regulation and disease
- Balance, Gait, and Falls Prevention
- Trace Elements in Health
Universidade Estadual de Londrina
2015-2021
There is evidence that immune-inflammatory, stress of reactive oxygen and nitrogen species (IO&NS) processes play a role in the neurodegenerative observed Parkinson's disease (PD). The aim present study was to investigate peripheral IO&NS biomarkers PD. We included 56 healthy individuals PD patients divided two groups: early stage late stage. Plasma lipid hydroperoxides (LOOH), malondialdehyde (MDA), nitric oxide metabolites (NOx), sulfhydryl (SH) groups, catalase (CAT) activity, superoxide...
Evidences have shown that physiotherapy programs may improve the balance of individuals with Parkinson's disease (PD), although it is not clear which specific exercise program better.The aim this study was to compare effectiveness versus resistance training on postural control measures in PD patients.Randomized controlled trial.The conducted a outpatient clinic university hospital.A total 40 participants were randomly divided into two groups: (BT) and (RT).The BT group focused training,...
Background: Parkinson's disease (PD) is a neurodegenerative disorder characterized by complex interplay between peripheral and central inflammatory oxidative stress pathways. Keywords: Inflammation, iron metabolism, stress, disease, Peripheral biomarkers, Systemic disease.
Objetive: This study was designed to investigate the effectiveness of a physical therapy treatment protocol based in dual task training balance individuals with Parkinson's disease. Méthods: Nine patients were evaluated before and after program on an exercise task, 60 minutes, 2x/week. The following variables investigated: Unified Parkinson’s Disease Rating Scale (UPDRS), Balance Evaluation Systems Test (BESTest) measurements Protocol. Results: Significant differences found motor domain...
Parkinson's disease (PD) is characterized by degeneration of dopaminergic neurons in the substantia nigra and motor non-motor symptoms. Free radicals may play a role biochemical events that lead to neuronal death old age neurodegenerative diseases. Furthermore, oxidative stress apparent PD. New therapeutic approaches slow or halt progression have been proposed. Antioxidants, free radical scavengers, trophic factors, monoamine oxidase inhibitors all identified as potential agents for...