Matthew B. Panzer

ORCID: 0000-0002-4500-9442
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About
Contact & Profiles
Research Areas
  • Automotive and Human Injury Biomechanics
  • Traumatic Brain Injury Research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Traffic and Road Safety
  • Injury Epidemiology and Prevention
  • Elasticity and Material Modeling
  • Disaster Response and Management
  • Spine and Intervertebral Disc Pathology
  • Cardiac Arrest and Resuscitation
  • Advanced Neuroimaging Techniques and Applications
  • Musculoskeletal pain and rehabilitation
  • Transportation Safety and Impact Analysis
  • Agriculture and Farm Safety
  • Lower Extremity Biomechanics and Pathologies
  • Foot and Ankle Surgery
  • Bone fractures and treatments
  • Sports injuries and prevention
  • Orthopaedic implants and arthroplasty
  • Medical Imaging and Analysis
  • Traumatic Ocular and Foreign Body Injuries
  • Human-Automation Interaction and Safety
  • Functional Brain Connectivity Studies
  • Advanced MRI Techniques and Applications
  • Tendon Structure and Treatment
  • High-Velocity Impact and Material Behavior

University of Virginia
2016-2025

Tufts University
2023

Medical College of Wisconsin
2017

Philadelphia University
2017

University of Pennsylvania
2017

CURE International UK
2017

Duke University
2010-2014

Bridge University
2012

Charlottesville Medical Research
2012

Durham VA Medical Center
2011

Traumatic brain injuries (TBI) are one of the least understood to body. Finite element (FE) models have been crucial for understanding concussion and developing injury mitigation systems; however, experimental deformation data currently used validate these limited. The objective this study was develop a methodology investigation in situ three-dimensional during pure rotational loading head, using sonomicrometry. Sonomicrometry uses ultrasonic pulses measure dynamic distances between...

10.1089/neu.2017.5362 article EN Journal of Neurotrauma 2017-11-28

Bicycle helmets are shown to offer protection against head injuries. Rating methods and test standards used evaluate different helmet designs safety performance. Both strain-based injury criteria obtained from finite element brain models metrics derived global kinematic responses can be Little is known about how or would rank rate helmets. The objective of this study was determine eight based on kinematics a large number bicycle (n=17) subjected oblique impacts. results showed that the...

10.1007/s10439-020-02703-w article EN cc-by Annals of Biomedical Engineering 2021-01-21

Abstract With the growing rate of traumatic brain injury (TBI), there is an increasing interest in validated tools to predict and prevent injuries. Finite element models (FEM) are valuable estimate tissue responses, probability TBI, guide development safety equipment. In this study, we developed anisotropic pig multi-scale FEM by explicitly embedding axonal tract structures utilized model simulate experimental TBI piglets undergoing dynamic head rotations. Binary logistic regression,...

10.1007/s10237-019-01273-8 article EN cc-by Biomechanics and Modeling in Mechanobiology 2019-12-06

Traumatic brain injury (TBI) is a significant public health burden, and the development of advanced countermeasures to mitigate prevent these injuries during automotive, sports, military impact events requires an understanding intracranial mechanisms related TBI. In this study, efficacy tissue-level metrics for predicting TBI was evaluated using finite element reconstructions from comprehensive, multi-species database. The database consisted human volunteer tests, laboratory-reconstructed...

10.1089/neu.2020.7445 article EN Journal of Neurotrauma 2021-01-15

10.1016/j.medengphy.2011.05.004 article EN Medical Engineering & Physics 2011-06-26

In Brief BACKGROUND Military service members are often exposed to at least one explosive event, and many blast-exposed veterans present with symptoms of traumatic brain injury. However, there is little information on the intensity duration blast necessary cause METHODS Varying shock tube blasts were focused head anesthetized ferrets, whose thorax abdomen protected. Injury evaluations included physiologic consequences, gross necropsy, histologic diagnosis. The resulting apnea, meningeal...

10.1097/ta.0b013e31825a760e article EN Journal of Trauma and Acute Care Surgery 2012-07-25

Many soldiers returning from the current conflicts in Iraq and Afghanistan have had at least one exposure to an explosive event a significant number symptoms consistent with traumatic brain injury. Although blast injury risk functions been determined validated for pulmonary injury, there is little information on levels necessary cause Anesthetized male New Zealand White rabbits were exposed varying of shock tube focused head, while their thoraces protected. The specimens euthanized evaluated...

10.1089/neu.2009.1207 article EN Journal of Neurotrauma 2011-04-04

Recent studies have shown an increase in the frequency of traumatic brain injuries related to blast exposure. However, mechanisms that cause neurotrauma are unknown. Blast research using computational models has been one method elucidate response blast, and identify possible mechanical correlates injury. model validation against experimental data is required ensure output representative vivo biomechanical response. This study exposed porcine subjects primary overpressures generated a...

10.3389/fneur.2012.00070 article EN cc-by Frontiers in Neurology 2012-01-01

Traumatic brain injuries (TBI) are a substantial societal burden. The development of better technologies and systems to prevent and/or mitigate the severity injury requires an improved understanding mechanisms injury, more specifically, how head impact exposure relates deformation. Biomechanical investigations have used computational models identify these relations, but experimental deformation data needed validate support their conclusions. objective this study was generate dataset...

10.1089/neu.2019.6847 article EN Journal of Neurotrauma 2020-01-18

Abstract The emergence of wearable strain sensors in soft electronics has the potential to revolutionize healthcare and robotics. However, current are based on petroleum‐based conductive composites that have a limited range. Ionic conductors such as hydrogels offer expanded range but poor long‐term stability restricted temperature operating window. Deep eutectic solvents (DESs) promising nonaqueous electrolytes alternatives with green credentials. By combining DES biopolymers, transient...

10.1002/admi.202300536 article EN cc-by Advanced Materials Interfaces 2023-09-28

Due to the prominent role of improvised explosive devices (IEDs) in wounding patterns U.S. war-fighters Iraq and Afghanistan, blast injury has risen a new level importance is recognized be major cause injuries brain. However, an risk-function for microscopic, macroscopic, behavioral, neurological deficits yet defined. While operational can very complex thus difficult analyze, simplified model would facilitate studies correlating biological outcomes with biomechanics define tolerance...

10.3389/fneur.2012.00023 article EN cc-by Frontiers in Neurology 2012-01-01
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