A5042382495- Sex work and related issues
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- Posttraumatic Stress Disorder Research
- Resilience and Mental Health
- Hemoglobinopathies and Related Disorders
- HIV-related health complications and treatments
- Child Nutrition and Water Access
- Malaria Research and Control
- Traumatic Brain Injury Research
- Epilepsy research and treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS drug development and treatment
- HIV/AIDS Impact and Responses
- Global Public Health Policies and Epidemiology
- Global Maternal and Child Health
- Iron Metabolism and Disorders
- Poverty, Education, and Child Welfare
- Suicide and Self-Harm Studies
- Tuberculosis Research and Epidemiology
- Simulation-Based Education in Healthcare
- Mosquito-borne diseases and control
- Mindfulness and Compassion Interventions
- COVID-19 and healthcare impacts
South African Medical Research Council
2023-2025
Stellenbosch University
2023-2025
Makerere University
2018-2025
The AIDS Support Organization
2020-2025
Gulu University
2015-2024
University College London
2023-2024
Mulago Hospital
2023
MRC Clinical Trials Unit at UCL
2023
Gulu Hospital
2017
BackgroundIn sub-Saharan Africa, health-care provision for chronic conditions is fragmented. The aim of this study was to determine whether integrated management HIV, diabetes, and hypertension led improved rates retention in care people with diabetes or without adversely affecting HIV viral suppression among when compared standard vertical medium large health facilities Uganda Tanzania.MethodsIn INTE-AFRICA, a pragmatic cluster-randomised, controlled trial, we randomly allocated primary...
Trace amine-associated receptor 1 (TAAR1) agonism shows promise for treating psychosis, prompting us to synthesise data from human and non-human studies.
<ns3:p>Background Exercise for post-traumatic stress disorder (PTSD) is a potentially effective adjunct to psychotherapy. However, the biopsychosocial mechanisms of exercise are not well understood. This co-produced living systematic review synthesizes evidence from human and non-human studies. Methods We Included controlled studies involving searches multiple electronic databases (until 31.10.23). Records were screened, extracted, assessed risk bias, reconciled by two independent reviewers....
<ns3:p>Background Exercise for post-traumatic stress disorder (PTSD) is a potentially effective adjunct to psychotherapy. However, the biopsychosocial mechanisms of exercise are not well understood. This co-produced living systematic review synthesizes evidence from human and non-human studies. Methods We Included controlled studies involving searches multiple electronic databases (until 31.10.23). Records were screened, extracted, assessed risk bias, reconciled by two independent reviewers....
In anxiety, depression and psychosis, there has been frustratingly slow progress in developing novel therapies that make a substantial difference practice, as well predicting which treatments will work for whom what contexts. To intervene early the process deliver optimal care to patients, we need understand underlying mechanisms of mental health conditions, develop safe effective interventions target these mechanisms, improve our capabilities timely diagnosis reliable prediction symptom...
<ns3:p>Background Exercise can play an important role in reducing symptom severity and improving functional impairment patients with posttraumatic stress disorder (PTSD). However, the precise mechanisms underpinning effect of exercise PTSD management are not fully understood. This living systematic review aims to synthesize triangulate evidence from non-human human studies gain insight into biopsychosocial through which reduces impairment. Methods Independent searches will be conducted...
ABSTRACT Introduction Academic proficiency is crucial for advancing learning goals, school advancement, and future economic security. Children with sickle cell anemia (SCA) in sub‐Saharan Africa (SSA) may be at risk of disease‐associated difficulties. Limited data exist on this topic among school‐age children the region. We aimed to assess academic a sample SCA Uganda compared unaffected controls. Methods This cross‐sectional study was conducted Kampala, Uganda. Participants were...
<ns3:p>Background Exercise can play an important role in reducing symptom severity and improving functional impairment patients with posttraumatic stress disorder (PTSD). However, the precise mechanisms underpinning effect of exercise PTSD management are not fully understood. This living systematic review aims to synthesize triangulate evidence from non-human human studies gain insight into biopsychosocial through which reduces impairment. Methods Independent searches will be conducted...
Currently, highly active antiretroviral therapy is unable to cure HIV/AIDS because of HIV latency. This study aimed at documenting medicinal plants used in the management Eastern Uganda so as identify phytochemicals with latency reversing potential. An ethnobotanical survey was conducted across eight districts Uganda. Traditional medicine practitioners were interviewed using semi-structured questionnaires. Qualitative and quantitative phytochemical tests respectively, performed determine...
Background . Globally, 15 countries, mainly in Sub-Saharan Africa, account for 80% of malaria cases and 78% related deaths. In Uganda, is endemic the mortality morbidity due to cause significant negative impact on economy. Gulu district, leading killer disease among children <5 years. 2015, high intensity infection Northern Uganda revealed a possible link between rainfall. However, available information influence climatic factors are scarce, conflicting, highly contextualized therefore...
Abstract Background Female sex workers operating in conflict-affected settings could be at a much greater risk of major depression. However, the epidemiology depression this population remains understudied. We aimed to determine prevalence and factors associated with among FSWs post-conflict Gulu district Northern Uganda. Methods conducted cross-sectional study 300 randomly selected adult female Gulu. utilized pre-tested semi-structured questionnaire, embedded MINI 7.0.0, gather information...
Abstract Background Long-acting reversible contraception (LARC) is the most effective and reliable option for female sex workers (FSWs) who desire future fertility. Unlike other contraceptive methods, LARC use requires only periodic users’ involvement at time of application re-application. However, a few studies on uptake among FSWs are available in Uganda. To fill this knowledge gap, we examined factors associated with post-conflict Northern Methods We conducted cross-sectional study adult...
<ns3:p>Background Exercise can play an important role in reducing symptom severity and improving functional impairment patients with posttraumatic stress disorder (PTSD). However, the precise mechanisms underpinning effect of exercise PTSD management are not fully understood. This living systematic review aims to synthesize triangulate evidence from non-human human studies gain insight into biopsychosocial through which reduces impairment. Methods Independent searches will be conducted...
Background Tuberculosis (TB) remains the leading cause of death among people living with HIV (PLHIV). To prevent TB PLHIV, Ugandan national guidelines recommend Isoniazid Preventive Therapy (IPT) across differentiated service delivery (DSD) models, an effective way delivering ART. DSD models include Community Drug Distribution Point (CDDP), Client-led ART Delivery (CCLAD), Facility-Based Individual Management (FBIM), Group (FBG), and Fast Track Refill (FTDR). Little is known about impact IPT...
<ns3:p>Background Exercise for post-traumatic stress disorder (PTSD) is a potentially effective adjunct to psychotherapy. However, the biopsychosocial mechanisms of exercise are not well understood. This co-produced living systematic review synthesizes evidence from human and non-human studies. Methods We Included controlled studies involving searches multiple electronic databases (until 31.10.23). Records were screened, extracted, assessed risk bias, reconciled by two independent reviewers....
Isoniazid preventive therapy (IPT) is effective in treating tuberculosis (TB) infection and hence limiting progression to active disease. However, the durability of protection, associated factors cost-effectiveness IPT remain uncertain low-and-middle income countries, Uganda inclusive. The Ministry health recommends a single standard-dose course for eligible people living with HIV (PLHIV). In this study we determined incidence, median time TB diagnosis among PLHIV on Antiretroviral (ART) who...
Abstract Background Dual contraception is an essential approach to mitigating the heightened risks of unintended pregnancies and sexually transmitted infections faced by female sex workers (FSWs). We determined prevalence factors associated with dual contraceptive use among FSWs in Northern Uganda. Methods A cross-sectional study was conducted Gulu city, Uganda between February, March 2023. Purposively selected aged 18 years or older who provided verbal informed consent were enrolled study....
Female sex workers (FSWs) live and work in high-risk environments, experience high levels of adversity, have multigenerational trauma that can negatively affect their children. Yet not much is known about the prevalence victimization (i.e., exposure to maltreatment trauma) among children FSWs. This study compared lifetime adolescents FSWs non-FSWs Gulu City, Northern Uganda.A comparative cross-sectional was conducted (10-17 years) enrolled Children At-Risk Parents (CARP) study. included 147...
To determine the prevalence and associated factors of client-perpetrated gender-based violence among female sex workers in conflict-affected Northern Uganda.We conducted a cross-sectional study Gulu district Uganda.The participants included 300 aged 18+ years. The were selected using simple random sampling from database maintained at national non-governmental organisation Gulu.The outcome measure was self-reported exposure to violence.We used pretested semistructured questionnaire collect...