To explore the longitudinal changes in retinal and choroidal thickness their relation with onset of type 1 diabetes mellitus (T1DM) children.

Objective Solitary fibrous tumor (SFT) is an uncommon mesenchymal neoplasm that exhibits a broad spectrum of biological behaviors. Few studies relative to clinical-pathologic features and radiologic manifestations SFTs have been reported. This study aimed correlate the findings with clinical histopathologic features. Methods The clinical, surgical, records; CT or MR images in 38 pathologically proved cases were retrospectively evaluated. Results All tumors seen as oval (n=18) irregular...

To determine the ability of anterior segment optical coherence tomography (AS-OCT) in measuring distance from corneoscleral limbus to insertion site horizontal extraocular muscles adult patients with strabismus.A total 16 strabismus were recruited for this study. The limbus-insertion distances rectus measured AS-OCT preoperatively and calipers intraoperatively. intraclass correlation coefficient (ICC), Pearson's coefficients, Bland-Altman plots used evaluate degree agreement between two...

The purpose of this study was to determine the specific sonographic features primary thyroid lymphoma and its color Doppler pattern compared nodular goiter.The findings for 13 surgically proven lymphomas were analyzed those 27 goiters.In accordance with suggested pathologic patterns, patterns could be classified into diffuse or segmental types based on distribution hypoechoic echogenic structures within lesions. Some common characteristics suggesting malignancy not facilitate differentiation...

Purpose: To analyze the characteristics of ocular surface microbial composition in children and adolescents with diabetes mellitus dry eye (DE) by tear analysis. Methods: We selected 65 aged 8 to 16 years DE non–DE 33 healthy same age group from Shanghai Children Adolescent Diabetes Eye Study. Tears were collected for high-throughput sequencing V3 V4 region 16S rRNA. The microbiota diabetic (DM-DE; n = 31), (DM-NDE; 34), (NDM; 33) groups studied. QIIME2 software was used each group. Results:...

Purpose To study changes in the thickness of retinal nerve fiber layer (RNFL) and ganglion cell (GCL) children with type 1 diabetes mellitus (T1DM) without visual impairment or diabetic retinopathy (DR) after 2 years follow-up analyze associated factors.Methods Thirty-seven T1DM were enrolled this study. All underwent a complete ophthalmologic evaluation that included swept-source optical coherence tomography at baseline follow-up. Changes RNFL GCL compared among follow-up.Results The...

This study compares the ocular biometry with or without myopia in children type 1 diabetes mellitus (T1DM) and healthy China to analyse difference between T1DM children.A case-control was conducted at Children's Hospital of Fudan University. The were divided into four subgroups depending on non-myopia, non-DM. participants evaluated for anterior chamber depth (ACD), lens thickness (LT), axial length (AL), average keratometry (K) power (P). Furthermore, cycloplegic refraction performed...

Abstract Background To investigate whether iris blood flow and thickness at the smooth muscle region affect pupil diameter rest after drug-induced mydriasis in patients with type 1 diabetes mellitus (T1DM) 2 (T2DM). Methods T1DM healthy children were recruited from SCADE cohort. T2DM adults undergoing cataract surgery Shanghai General Hospital. Iris vessel density, (PD) measured both resting states. density was by optical coherence tomography angiography (OCTA), PD a pupilometer, regions...

To compare ocular biometry between children with type 1 diabetes mellitus (T1DM) and healthy in China to determine the correlation of glycosylated hemoglobin (HbA1c) level duration. A case-control study was conducted at Children's Hospital Fudan University T1DM children. The participants were evaluated for central corneal thickness (CCT), anterior chamber depth (ACD), lens (LT), K1 K2 keratometry, axial length (AL); also cycloplegic refraction performed, spherical equivalent (SE) acquired....

Purpose: To investigate the incidence and risk factors of dry eye in children with diabetes mellitus (DM) over a period 3 years. Methods: Children adolescents DM (age: 3-14 years) from Shanghai Adolescent Diabetes Eye (SCADE) study cohort who did not have January 2018 were followed-up for years re-examined 2021, rate calculated. Results: Forty came follow-up 2021. Nine them diagnosed eye, resulting 3-year 22.5% an annual mean 7.5% eye. Univariate regression analysis confirmed that decreased...

To investigate the correlation between demodicosis and pediatric chalazia.A case-control prospective study was conducted at Children's Hospital of Fudan University December 2018 January 2019. One hundred one consecutive patients with chalazia 42 without underwent eyelash sampling Demodex examination using light microscopy, mite presence count were documented.The prevalence group much higher than that control (3.06 ± 3.48 vs 0.64 1.17; P ≤ .001; 73.3% 35.7%, .001). The multiple subgroup...

Microbiome changes on the ocular surface may cause dry eyes. A metagenome assay was used to compare microbiome composition and function of between diabetic children adolescents with eye, without normal children.Twenty aged 8 16 diabetes were selected from Shanghai Children Adolescent Diabetes Eye Study. Ten healthy belonging same age group outpatient clinic during period. The participants classified into eye (DM-DE group, n = 10), non-dry (DM-NDE 10) (NDM 10). conjunctival sac swab collected...

Subretinal prostheses are a novel technology for restoring useful vision in patients with retinitis pigmentosa or age-related macular degeneration. We characterize the surgical implantation technique and functional time window of an acute rabbit eye model testing human subretinal prostheses.Retinal were implanted subretinally 26 rabbits using two-step technique. Fundus imaging, fluorescein fundus angiography, optical coherence topography (OCT) conducted postoperatively from days 1 to 21...

Diabetes mellitus may compromise the vasculature of iris, thereby leading to severe vision-threatening complications. This study aimed investigate differences in iris blood flow indices between pediatric type 1 diabetes (T1DM) patients and adult 2 (T2DM) patients.This was a cross-sectional study. Pediatric T1DM healthy children were members Shanghai Children Adolescent Eye (SCADE) cohort who visited Hospital February 2022. The T2DM adults General from October 2021 January Iris OCTA acquired...

Using electrophysiology (ERG) to investigate the early alterations of retinal function in diabetic children and adolescents without retinopathy (DR) or visual impairment (VI).We recorded compared data full-field flicker ERGs between 59 normal subjects 60 with type 1 diabetes mellitus (T1DM) from Children's Hospital Fudan University Shanghai.In both groups, patients healthy controls were matched for age, gender, weight, height, BMI, intraocular pressure (IOP), best-corrected acuity (BCVA)....

The placenta links feto-maternal circulation for exchanges of nutrients, gases and metabolic wastes between the fetus mother, which is essential pregnancy process. allantois mesodermal components amnion, chorion yolk sac are derived from extraembryonic mesoderm (Ex-Mes), however, mechanisms underlying those progenitors contributing to distinct regulation interactions epithelium during chorioallantoic fusion labyrinth formation remains unclear. Isl1 expressed in Ex-Mes allantois. We analyzed...

Only the basic wall thickness of drum is taken under consideration in traditional parallel grooved strength analysis, which quite conservative for ignoring groove. So this paper, it aimed at comparing simulation results two models with and without groove analyzing stress distribution structure, provides reference structure design optimization drum.

The parallel grooved multi-layer winding drum can wind rapidly and reliably compared to traditional drum, because of the special groove which is generated by circular helical motion. present paper represented key stage for was motion in first circle on second layer, simulated ADAMS under several factors as fleet angle, linear velocity rope tension. Taguchi method adopted estimate performance through two simulation outputs, including time delay ideal sum amplitude error during delayed time....

Background The measurement of the extraocular muscle is critical for diagnosis diseases,but conventional medical imaging techniques present some shortcomings because contact pattern.The anterior segment optical coherence tomography (OCT) thought to be an in vivo noninvasive diagnostic method.Objective This clinical study attempted seek available approach evaluation anatomic structure human horizontal rectus insertion with Visante OCT.Methods One hundred and fourteen eyes 58 subjects were...

Abstract Purpose: To investigate differences in iris blood flow indices between pediatric type 1 diabetes mellitus (T1DM) patients and adult 2 (T2DM) patients. Methods: This was a cross-sectional study. Pediatric T1DM healthy children were members of the Shanghai Children Adolescent Diabetes Eye (SCADE) cohort who visited Hospital February 2022. The T2DM adults General from October 2021 to January Iris OCTA acquired through Cirrus HD-OCT 5000 angiography system (Carl Zeiss Meditec, Inc.). A...