A5001587364- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Memory and Neural Computing
- Spacecraft Dynamics and Control
- GaN-based semiconductor devices and materials
- Covalent Organic Framework Applications
- Semiconductor materials and devices
- Terahertz technology and applications
- Adaptive Control of Nonlinear Systems
- Astro and Planetary Science
- Supercapacitor Materials and Fabrication
- Space Satellite Systems and Control
- Ferroelectric and Negative Capacitance Devices
- Dynamics and Control of Mechanical Systems
- Vibration and Dynamic Analysis
- Advanced Nanomaterials in Catalysis
- Gas Dynamics and Kinetic Theory
- Electrocatalysts for Energy Conversion
- Aerospace Engineering and Control Systems
- Stability and Control of Uncertain Systems
- Advanced Control Systems Optimization
- Control Systems and Identification
- Thermal Radiation and Cooling Technologies
- Elasticity and Wave Propagation
- Vibration Control and Rheological Fluids
- Nanoplatforms for cancer theranostics
National Cheng Kung University
2020-2024
Kaohsiung Medical University Chung-Ho Memorial Hospital
2024
Kaohsiung Municipal Ta-Tung Hospital
2024
University of California, Santa Barbara
2023
National Yang Ming Chiao Tung University
2007-2022
Bridge University
2022
Mackay Medical College
2022
University Research Co (United States)
2022
National Taiwan University
2020
Chang Jung Christian University
2012-2016
MicroRNAs (miRNAs) are small non-coding RNAs of ∼ 22 nucleotides that involved in negative regulation mRNA at the post-transcriptional level. Previously, we developed miRTarBase which provides information about experimentally validated miRNA-target interactions (MTIs). Here, describe an updated database containing 422 517 curated MTIs from 4076 miRNAs and 23 054 target genes collected over 8500 articles. The number by strong evidence has increased ∼1.4-fold since last update 2016. In this...
Abstract Owing to their fascinating characteristics, metal−organic frameworks (MOFs) have attracted great attention and been utilized in a range of applications. The use MOFs electrochemical sensors has become an emerging subfield since 2013. However, the poor chemical stability aqueous solutions low electrical conductivity most two main concerns that hinder pristine electroanalytical systems. In this short review, we aim focus on these issues provide perspectives regarding opportunities...
In this study, nanocrystals of a cerium-based metal–organic framework (Ce-MOF), Ce-MOF-808, are directly grown on the surface carboxylic acid-functionalized carbon nanotubes (CNTs) by facile one-step solvothermal synthesis method. Ce-MOF–CNT nanocomposites with various Ce-MOF-to-CNT ratios synthesized, and their crystallinity, morphology, porosity, electrical conductivity examined. The redox-hopping electrochemical behaviors pristine Ce-MOF in aqueous electrolytes investigated, suggesting...
Gastric cancer is currently the fourth leading cause of cancer-related death worldwide. often diagnosed at advanced stages and outcome treatment poor. Therefore, identifying new therapeutic targets for this urgently needed. Integrin alpha 2 (ITGA2) subunit beta 1 form a heterodimer transmembrane receptor extracellular matrix, an important molecule involved in tumor cell proliferation, survival migration. α2β1 over-expressed on variety cells, but low or absent most normal organs resting...
Silver nanoparticles (NPs) are installed into a porphyrinic zirconium-based metal–organic framework (Zr-MOF), NU-902, through postsynthetic modification followed by an ion-exchange process. Both the framework-immobilized Ag(I) ions and partially reduced silver NPs confined within nanopores of NU-902 with size around 3 nm found in obtained composite. As both linkers electrocatalysts for oxidation nitrite, nanocomposite can be applied electrochemical nitrite sensor, resulting sensing...
Rationale: Triple-negative breast cancer (TNBC), which has the highest recurrence rate and shortest survival time of all cancers, is in urgent need a risk assessment method to determine an accurate treatment course. Recently, miRNA expression patterns have been identified as potential biomarkers for diagnosis, prognosis, personalized therapy. Here, we investigate combination candidate miRNAs clinically applicable signature that can precisely predict relapse TNBC patients after surgery....
To obtain renewable and clean fuels, exploration of effective electrocatalysts is highly desirable due to the sluggish kinetics water splitting. In this study, oxygen plasma-activated hybrid structure Ni-Fe Prussian blue analogue (PBA) interconnected by carbon nanotubes (O-CNT/NiFe) reported as a electrocatalytic material for evolution reaction (OER). The performance significantly influenced different mass ratios CNTs PBA. Benefiting from conductive well ordered distributed metal sites in...
In this study, metallic molybdenum nanoparticles confined in the nanopores of a zirconium-based MOF (Zr-MOF), MOF-808, are prepared by self-limiting decoration spatially isolated Mo(VI) sites on hexa-zirconium nodes followed electrochemical reduction to Mo. The obtained pore-confined Mo exhibits reversible redox activity neutral aqueous electrolyte and serves as pseudocapacitive material for negative electrodes. By introducing another MOF-based that can be used positive electrodes,...
The incorporation of iron into pristine transition metal oxides has been considered as an effective strategy to enhance the electrocatalytic activity toward oxygen evolution reaction (OER). However, introduction other metals in diverse catalytic systems using a precisely controllable method remained great challenge. In this study, facile is proposed by Prussian blue analogues (PBAs) with tunable composition template synthesize various Co–Fe molar ratios spinel oxides. iron–cobalt oxide (FeCo...
3D SERS microneedles with self-assembled AuNPs were fabricated tannic acid (chemical glue and reductant) on polylactic for in-depth chemical biomolecular analysis, LOD values below 200 ppb small molecules 102 CFU cm-2 bacteria. The MB/Au-microneedles used photodynamic therapy SERS-monitored photosensitizer degradation.
ABSTRACT This retrospective cohort study investigated whether Paxlovid (nirmatrelvir/ritonavir) use during the acute phase of mild‐to‐moderate COVID‐19 reduces risk ischemic or hemorrhagic stroke occurring more than 3 months post‐diagnosis, a condition classified as long COVID. Utilizing TriNetX electronic health records comprising 118 million patients in United States, adults aged 18 years older with confirmed diagnoses from 2022 to 2023 were categorized into (administered within 5 days...
Terahertz emission from indium nitride (InN) nanorods and InN film grown by molecular-beam epitaxy on Si(111) substrates has been investigated. is at least three times more intense than that depends strongly the size distribution of nanorods. Surface electron accumulation effectively screens out photo-Dember field in layer formed under surface. The with considerably large diameter thickness are found to be dominant terahertz radiation nanorod arrays.
Terahertz time-domain spectroscopy has been used to investigate terahertz conductivity and dielectric response of indium nitride (InN) nanorod array epitaxial film. The complex InN film is well fitted by the Drude model, while negative imaginary nanorods can be described using Drude-Smith model. electron mobility 1217±58cm2∕Vs, that 80±5cm2∕Vs. reduced carriers for latter attributed restricted carrier transport within nanorods.
We report a significant enhancement in terahertz emission from the indium nitride (InN) films grown along axis (a-plane InN), relative to InN c axis. The primary radiation mechanism of a-plane film is found be due acceleration photoexcited carriers under polarization-induced in-plane electric field perpendicular axis, which effectively enhances geometrical coupling out semiconductor. In addition, azimuthal angle dependence measurement shows that p-polarized output consists large angularly...
In this study, three topologically distinct zirconium-based metal–organic frameworks (Zr-MOFs), i.e., UiO-66, NU-902, and PCN-222, were synthesized employed as porous supports to immobilize Pd nanoparticles (NPs) via the solvothermal deposition in MOFs (SIM) technique. Physicochemical characterizations show that structural, morphological, textural features of pristine Zr-MOFs are mainly preserved upon incorporation NPs. It is shown sizes NPs controllable by pore confinement Zr-MOFs. Reaction...
Abstract In this study, a strategy that can result in the polyaniline (PANI) solely confined within nanopores of metal–organic framework (MOF) without forming obvious bulk PANI between MOF crystals is developed. A water‐stable zirconium‐based MOF, UiO‐66‐NH 2 , selected as material. The polymerization aniline initiated acidic suspension nanocrystals presence excess poly(sodium 4‐styrenesulfonate) (PSS). Since pore size too small to enable insertion bulky PSS, quick formation pore‐confined...
Abstract Nanocrystals of a zirconium‐based metal‐organic framework (MOF), UiO‐66, are grown on the surface carboxylic acid‐functionalized multi‐walled carbon nanotubes (CNT) at room temperature to synthesize UiO‐66‐CNT nanocomposites with tunable MOF‐to‐CNT ratios. The porosity, crystallinity, morphology, and electrical conductivity nanocomposite characterized. Spatially dispersed iridium sites thereafter installed defect presented within entire UiO‐66 crystals in these by self‐limiting...
Covers advancements in spacecraft and tactical strategic missile systems, including subsystem design application, mission analysis, materials structures, developments space sciences, processing manufacturing, operations, applications of technologies to other fields.
In this study, spatially dispersed redox-active iridium sites are installed on the nodes of a zirconium-based metal–organic framework (MOF), UiO-66, utilizing self-limiting solution-phase solvothermal deposition in MOF technique. Thin films resulting iridium-decorated UiO-66 then fabricated conducting substrates by three distinct approaches: drop-casting, spin-coating, and bottom-up methods. The redox-hopping electrochemical behaviors thin methods investigated. findings indicate that rate...
The aim was to compare the genetic information of varicose vein patients with that a healthy population attempting identify certain significant associations.Patients' clinical characteristics and demographics were collected, their samples examined. results compared one thousand sex-matched controls from Taiwan Biobank database. Clinical-Etiology-Anatomy-Pathophysiology classification applied for further subgroup analysis.After comparison ninety-six controls, two single nucleotide...
Spatially dispersed redox-active iridium sites are immobilized throughout the porous framework of a zirconium-based metal–organic (MOF), UiO-66, to enable charge hopping in MOF. The resulting within UiO-66 not only permit redox hopping-based electron transport MOF aqueous electrolytes, but also exhibit electrocatalytic activity for oxidation nitrite. pH electrolyte this electrocatalysis is optimized, and mechanism occurring on Ir-decorated thin films investigated. material further applied...
The anti-angiogenic fusion protein RBDV-IgG1 Fc (RBDV), which comprises the receptor-binding domain of vascular endothelial growth factor-A (VEGF-A), has shown antitumour effects by reducing angiogenesis in vivo. This study used cationic lipoplex lipo-PEG-PEI-complex (LPPC) to simultaneously encapsulate both RBDV targeting and plasmid (pRBDV) without covalent bonds assess VEGFR gene therapy mice with melanoma vivo.LPPC protected therapeutic transgene from degradation DNase, LPPC/RBDV...
When performing radiofrequency ablation for thyroid nodules, it is essential to avoid thermal injury the recurrent laryngeal nerve. This porcine animal model study used continuous intraoperative neuromonitoring investigate safety parameters of ablation.