A5065696059- Topic Modeling
- Natural Language Processing Techniques
- Spectroscopy and Chemometric Analyses
- Spectroscopy Techniques in Biomedical and Chemical Research
- Optical Imaging and Spectroscopy Techniques
- Metal Forming Simulation Techniques
- Manufacturing Process and Optimization
- Cardiac Arrest and Resuscitation
- Advanced machining processes and optimization
- Control Systems and Identification
- Mechanical Behavior of Composites
- Wastewater Treatment and Nitrogen Removal
- Fault Detection and Control Systems
- Titanium Alloys Microstructure and Properties
- Surface Treatment and Residual Stress
- Advanced Surface Polishing Techniques
- Additive Manufacturing Materials and Processes
- Advanced Control Systems Design
- Membrane Separation Technologies
- Advanced Control Systems Optimization
- Metallurgy and Material Forming
- Infant Nutrition and Health
- 3D Printing in Biomedical Research
- Non-Invasive Vital Sign Monitoring
- Welding Techniques and Residual Stresses
National Yang Ming Chiao Tung University
2016-2025
Tianjin University
2007-2025
University of Science and Technology of China
2024
Guangzhou Medical University
2013-2024
Nanjing University of Aeronautics and Astronautics
2011-2024
UNSW Sydney
2020-2024
Guangdong Medical College
2024
State Key Laboratory of Polymer Physics and Chemistry
2024
Chinese Academy of Sciences
2024
Changchun Institute of Applied Chemistry
2024
MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which negatively regulate the gene expression at post-transcriptional level. This study describes an update miRTarBase (http://miRTarBase.mbc.nctu.edu.tw/) that provides information about experimentally validated miRNA-target interactions (MTIs). The latest expanded it to identify systematically Argonaute-miRNA-RNA from 138 crosslinking and immunoprecipitation sequencing (CLIP-seq) data sets were generated by 21...
MicroRNAs (miRNAs) are small non-coding RNAs of ∼ 22 nucleotides that involved in negative regulation mRNA at the post-transcriptional level. Previously, we developed miRTarBase which provides information about experimentally validated miRNA-target interactions (MTIs). Here, describe an updated database containing 422 517 curated MTIs from 4076 miRNAs and 23 054 target genes collected over 8500 articles. The number by strong evidence has increased ∼1.4-fold since last update 2016. In this...
Abstract Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of oral cavity and fourth leading malignancy cause cancer-related death in male population Taiwan. Most cases are detected at advanced stages, resulting poor prognosis. Therefore, improved detection early health disorders indispensable. The involvement bacteria inflammation their association with OSCC progression provide a feasible target for diagnosis. Due to nature neoplasms, diagnosis epithelial precursor...
Rice blast is one of the most serious plant diseases. Many rice management approaches require know-how experienced farmers or agronomists. Monitoring farm for disease detection labor intensive and time consuming. By using Internet Things (IoT) artificial intelligence (AI), we are able to detect diseases more efficiently. Existing AI IoT studies by images nonimage hyperspectral data, which manual operations obtain photographs data analysis. Also, image typically too late as may already spread...
Our previous study found that suppression of TRPM7 reduced neuronal death in adult rat ischemic brain injury. It was reported carvacrol blocked and attenuated injury an MCAO model. The effects on neonatal stroke remain unknown. This investigated the behavioral impairment after hypoxia-ischemia mice potential signaling pathway underlying these effects.Carvacrol inhibited current HEK293 cells over-expressing TRPM7-like hippocampal neurons a dose-dependent manner. Carvacrol (>200 μM)...
This paper proposes AgriTalk, an inexpensive Internet of Things (IoT) platform for precision farming soil cultivation. We conduct experiments on turmeric cultivation, which indicates that the quality is significantly enhanced through AgriTalk. Specifically, curcumin concentration up to 4500-5500 mg/100 g, five times more than existing products. demonstrate how intuitively configure connections between sensors and actuators with desired intelligence, effectively maintain AgriTalk farming....
Background Tertiary lymphoid structures (TLSs) are crucial in promoting and maintaining positive anti-tumor immune responses. The tumor stroma has a powerful immunosuppressive function that could exclude tumor-infiltrating lymphocytes from the beds lead to “cold” phenotype. TLSs percentage (TSP) significantly associated with prognosis of patients certain cancers. However, exact roles TSP their intrinsic relationship still largely unknown colorectal cancer (CRC). Methods were assessed using...
The microstructure evolution and strengthening mechanism of materials after shot peening have always been the focus research. In this paper, a novel coupled constitutive model was proposed to predict depth fine-grain 2060-T8 aluminum-lithium (Al–Li) alloy peening. Besides, combining numerical experimental methods, influences size on yield stress, dislocation density, crystal orientation Al–Li were systematically studied reveal mechanism. results show that larger sizes can significantly...
Abstract Background Existing methods for predicting protein solubility on overexpression in Escherichia coli advance performance by using ensemble classifiers such as two-stage support vector machine (SVM) based and a number of feature types physicochemical properties, amino acid dipeptide composition, accompanied with selection. It is desirable to develop simple easily interpretable method solubility, compared existing complex SVM-based methods. Results This study proposes novel scoring...
Glioblastoma, the most common and aggressive type of brain tumors, has devastatingly proliferative invasive characteristics. The need for finding a novel specific drug target is urgent as current approaches have limited therapeutic effects in treating glioblastoma. Xyloketal B marine compound obtained from mangrove fungus Xylaria sp. (No. 2508) South China Sea, displayed antioxidant activity protective on endothelial neuronal oxidative injuries. In this study, we used glioblastoma U251 cell...
Emerging evidence indicates that plant miRNAs can present within human circulating system through dietary intake and regulate gene expression. Hence we deduced comestible plants be identified in the public available small RNA sequencing data sets. In this study, abundant sequences from 410 plasma One particular miRNA miR2910, conserved fruits vegetables, was found to high relative amount samples. This miRNA, with same 6mer 7mer-A1 target seed as hsa-miR-4259 hsa-miR-4715-5p, predicted...
The dysbiosis of human gut microbiota is strongly associated with the development colorectal cancer (CRC). dysbiotic features transition from advanced polyp to early-stage CRC are largely unknown. We performed a 16S rRNA gene sequencing and enterotype-based analysis study. In addition Bacteroides- Prevotella-dominated enterotypes, we identified an Escherichia-dominated enterotype. found that were dissimilar in overall samples especially Besides higher abundance Fusobacterium, Enterococcus,...
Different geographical origins can lead to great variance in coffee quality, taste, and commercial value. Hence, controlling the authenticity of origin beans is importance for producers consumers worldwide. In this study, terahertz (THz) spectroscopy, combined with machine learning methods, was investigated as a fast non-destructive method classify geographic beans, comparing it popular including convolutional neural network (CNN), linear discriminant analysis (LDA), support vector (SVM)...
Osteoarthritis (OA) is a multifactorial joint disease associated with the deterioration of chondrocytes and inflammation. Treatment OA only aimed at reducing pain improving function. Recently, extracellular vesicles (EVs) secreted from stem cells have emerged as cell regenerative tool in several degenerative diseases, including OA. We hypothesised that induced pluripotent (iPSC)-derived EVs would be beneficial for regenerating therapy. Therefore, we to investigate iPSC-EVs' effects on...
Abstract β‐lactoglobulin (β‐LG), one of the most investigated proteins, is a major bovine milk protein with predominantly β structure. The structural function only α‐helix three turns at C‐terminus unknown. Vitamin D 3 binds to central calyx formed by β‐strands. Whether there are two vitamin binding‐sites in each β‐LG molecule has been subject controversy. Here, we report second binding site identified synchrotron X‐ray diffraction (at 2.4 Å resolution). In mode, aliphatic tail clearly...