A5001391770- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Tissue Engineering and Regenerative Medicine
- Neuroscience and Neural Engineering
- Electrospun Nanofibers in Biomedical Applications
- Advanced Sensor and Energy Harvesting Materials
- Nanoplatforms for cancer theranostics
- Blood Pressure and Hypertension Studies
- Medical Research and Treatments
- Physical Activity and Health
- Bone Tissue Engineering Materials
- Nanofabrication and Lithography Techniques
- COVID-19 Clinical Research Studies
- MicroRNA in disease regulation
- Luminescence and Fluorescent Materials
- Systemic Lupus Erythematosus Research
- Pluripotent Stem Cells Research
- Photodynamic Therapy Research Studies
- Child Nutrition and Water Access
- Transcranial Magnetic Stimulation Studies
- Polymer composites and self-healing
- Cardiac electrophysiology and arrhythmias
- Peripheral Artery Disease Management
- Abdominal vascular conditions and treatments
- Ultrasound in Clinical Applications
Hubei University of Science and Technology
2025
University of Toronto
2020-2024
Anhui University of Traditional Chinese Medicine
2024
University Health Network
2023-2024
Toronto General Hospital
2024
Jiangxi University of Traditional Chinese Medicine
2023-2024
Jiangnan University
2024
Wuxi Fourth People's Hospital
2024
Wenzhou Medical University
2021
Dongyang People's Hospital
2021
The ability to precisely control the properties of natural polymers and fabricate three-dimensional (3D) structures is critical for biomedical applications. In this work, we report printing complex 3D made soft polysaccharide (chitosan) inks directly in air at room temperature. We perform a comprehensive characterization process by analyzing effect ink (i.e., rheological solvent evaporation) process-related parameters nozzle diameter, robot velocity, applied pressure). effects neutralization...
Skeletal muscle displays a marked accumulation of denervated myofibers at advanced age, which coincides with an acceleration atrophy. In this study, we evaluated the hypothesis that in age is due to failed reinnervation by examining from young adult (YA) and very old (VO) rats murine model sporadic denervation secondary neurotrypsin over-expression (Sarco mouse). Both aging rat Sarco mouse exhibited fiber-type grouping, consistent repeating cycles reinnervation, yet VO muscle, rapsyn...
The ability to produce complex micro‐ or nanostructures from naturally derived hydrogels is significant for biomedical applications. However, precisely controlled architectures of soft are difficult be achieved due their limited mechanical properties. Despite intensive research, challenges persist fabricate with ordered structures and adequate biological properties mimicking native tissues. In this work, a 3D printing technique proposed chitosan hydrogel highly flexible organized microfiber...
Abstract We developed a heart-on-a-chip platform that integrates highly flexible, vertical, 3D micropillar electrodes for electrophysiological recording and elastic microwires the tissue’s contractile force assessment. The high aspect ratio microelectrodes were 3D-printed into device using conductive polymer, poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS). A pair of quantum dots/thermoplastic elastomer nanocomposite printed to anchor tissue enable continuous flexible...
Epicardial cells (EPIs) form the outer layer of heart and play an important role in development disease. Current heart-on-a-chip platforms still do not fully mimic native cardiac environment due to absence relevant cell types, such as EPIs. Here, using Biowire II platform, engineered tissues with epicardial inner myocardial structure are constructed, image analysis approach is developed track EPI migration a beating environment. Functional properties improve over two weeks culture. In...
The design of self-healable and stretchable devices from sustainable materials is increasingly attractive for various applications such as soft robotics, wearable sensors, biomedical devices.
There is an increasing need for 3D printing of metallic structures in a green and cost-effective way. Here, environment-friendly reusable ink was developed economical metal method. The composed steel micro powders, biodegradable polymer: chitosan, acetic acid deionized water. method consists of: (i) using the at room temperature, (ii) thermal treatments on as-printed that decompose polymer binder sinter (iii) optional step: infiltrating melted copper into sintered to achieve fully dense...
The successful translation of organ-on-a-chip devices requires the development an automated workflow for device fabrication, which is challenged by need precise deposition multiple classes materials in micro-meter scaled configurations. Many current heart-on-a-chip are produced manually, requiring expertise and dexterity skilled operators. Here, we devised scalable fabrication method to engineer a Biowire II multiwell platform generate human iPSC-derived cardiac tissues. This high-throughput...
Abstract The application and selection of marketing channels in agricultural cooperatives significantly impact their operational efficiency. To verify the effectiveness product distribution to establish a more systematic efficient channel network, this study first compares analyzes diversified using two-stage survey data from China. Then, static game model with complete information is constructed explore on efficiency under different contractual relationships. research surveyed interviewed...
The development of rural infrastructure plays an essential role in improving livelihoods and enhancing sustainable environmentally friendly agricultural production. However, little is known about whether enables the promotion resource-conserving agriculture reduces production costs. Understanding relationship between costs can provide significant information for policy-makers their efforts to promote resource-saving that beneficial environmental performance. This study contributes literature...
Abstract Background: Accumulating evidence has reported that physical activity (PA) is effective in reducing stroke and mortality. However, whether PA levels are associated with middle-aged elderly people Jiangxi Province of China remains unclear. In the present study, we evaluated association between risk China. Methods: A cross-sectional survey was conducted from November 2013 to August 2014, using standardized questionnaire forms measurements. Self-reported assessed international...
Bioelastomers are extensively used in biomedical applications due to their desirable mechanical strength, tunable properties, and chemical versatility; however, three-dimensional (3D) printing bioelastomers into microscale structures has proven elusive. Herein, a high throughput omnidirectional approach via coaxial extrusion is described that fabricates perfusable elastomeric microtubes of unprecedently small inner diameter (350-550 µm) wall thickness (40-60 µm). The versatility this shown...
Abstract Accumulating evidence has reported that prolonged periods of sedentary time have been recognized as a risk factor for cardiocerebrovascular disease. However, whether high levels behavior are associated with an increased disease in different regions remains unclear. The aim this study was to evaluate the association between and myocardial infarction (MI) stroke Jiangxi Province China. A cross-sectional survey conducted among 15,364 participants China from November 2013 August 2014,...
Application of cardiac patches to the heart surface can be undertaken provide support and facilitate regeneration damaged tissue following ischemic injury. Biomaterial composition is an important consideration in design patch materials as it governs host response ultimately prevent undesirable fibrotic response. Here, we investigate a novel material, poly (itaconate-
Adverse cardiac outcomes in COVID-19 patients, particularly those with preexisting disease, motivate the development of human cell-based organ-on-a-chip models to recapitulate injury and dysfunction for screening cardioprotective therapeutics. Here, we developed a heart-on-a-chip model study pathogenesis SARS-CoV-2 healthy myocardium established from induced pluripotent stem cell (iPSC)-derived cardiomyocytes model, mimicking aspects hypertensive disease by angiotensin II (Ang II). We...
Abstract Aim To evaluate the diagnostic value of interleukin-18 (IL-18) and troponin (TnI) in sepsis. Methods This retrospective analysis included 117 patients with sepsis (patient group) 92 subjects who attended regular physical examinations (control group). We compared IL-18 TnI expressions before treatment (T1) on day 5 (T2), 10 (T3) 15 (T4) treatment. Acute Physiology Chronic Health Evaluation II (APACHE II) guidelines were used to analyse correlation between IL-18, APACHE scores....
Lupus nephritis (LN) is one of the main risk factors contributing to morbidity and mortality systemic lupus erythematosus (SLE). This study aimed investigate potential role miR-485-5p in human LN.Quantitative real-time polymerase chain reaction was used for measurement levels. The levels interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) serum were determined by enzyme-linked immunosorbent assay. diagnostic LN evaluated receiver operating characteristic (ROC)...
Event Abstract Back to Solvent-cast 3D printing of Chitosan hydrogel scaffolds for guided cell growth Qinghua Wu1, Marion Maire2, Sophie Lerouge2, Daniel Therriault3 and Marie-Claude Heuzey1 1 École Polytechnique de Montréal, Chemical Engineering, Canada 2 technologie supérieure, LBeV- CHUM research center (CRCHUM) & Department Mechanical 3 Laboratory Multiscale Mechanics (LM2) Introduction: Hydrogels made natural polymers are interesting biomaterials because they simulate the aqueous...