A5045987915- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Systems and Practices
- Cardiac Valve Diseases and Treatments
- ECG Monitoring and Analysis
- Wireless Communication Networks Research
- Cardiomyopathy and Myosin Studies
- Cardiac pacing and defibrillation studies
- Ultrasound in Clinical Applications
- Advanced Wireless Network Optimization
- Advanced MIMO Systems Optimization
- Cardiovascular Health and Disease Prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Gout, Hyperuricemia, Uric Acid
- Pulmonary Hypertension Research and Treatments
- Atrial Fibrillation Management and Outcomes
- Advanced Wireless Communication Techniques
- Cardiac Structural Anomalies and Repair
- Hip and Femur Fractures
- Cardiac Arrhythmias and Treatments
- Chronic Disease Management Strategies
- Hospital Admissions and Outcomes
Blackpool Teaching Hospitals NHS Foundation Trust
2019-2025
University of Liverpool
2016-2024
Blackpool Victoria Hospital
2016-2024
City University of Hong Kong
2024
Hull York Medical School
2013-2018
Castle Hill Hospital
2011-2018
University of Hull
2005-2018
University of York
2016
Ninewells Hospital
2003-2015
University of Dundee
2002-2015
<h3>Importance</h3> Detailed information on the prevalence, associations, and consequences of anemia iron deficiency in epidemiologically representative outpatients with chronic heart failure (HF) is lacking. <h3>Objective</h3> To investigate epidemiology a broad range patients referred to cardiology clinic suspected HF. <h3>Design, Setting, Participants</h3> We collected clinical data, including hemoglobin, serum iron, transferrin saturation, ferritin concentrations, consecutive HF single...
Background and Purpose — The purpose of this study was to investigate renal function as a long-term predictor mortality in patients hospitalized for acute stroke. Methods This cohort done Scottish tertiary teaching hospital. Participants included 2042 (993 male) unselected consecutive stroke (mean age, 73 years) admitted hospital within 48 hours between1988 1994. Follow-up up 7 years. Main outcome measure all-cause mortality. Results total number deaths at the end follow-up 1026. Most...
Wearable haptics serve as an enhanced media to connect humans and VR/robots. The inevitable sweating issue in all wearables creates a bottleneck for wearable haptics, the sweat/moisture accumulated skin/device interface can substantially affect feedback accuracy, comfortability, create hygienic problems. Nowadays, typically gain performance at cost of sacrificing breathability, comfort, biocompatibility. Here, we developed fully integrated breathable haptic textile (FIBHT) solve these...
Abstract Background/Introduction Stress echocardiography is widely used to assess patients with chest pain. The clinical value of a positive or negative test result inform on likely longer-term outcomes when applied in real-world practice across national healthcare system has not been previously reported. Purpose We report patient outcome up five years after stress echocardiogram for undergoing clinically-indicated ischaemic heart disease real-world, multi-centre and determine the event-free...
Abstract Aims To assess the real world impact of updated clinical guidelines and literature on management patients undergoing stress echocardiography for assessment inducible ischaemia across a national health service. Methods Results A total 13,819 from 32 UK hospitals, referred between 2015-2023, were analysed two phases: phase 1 (2015-2020) 2 (2020-2023). Follow-up data one year was available 4,920 participants through NHS Digital. Patients in younger, presented with higher cardiovascular...
Abstract Aims Stress echocardiography is widely used to identify obstructive coronary artery disease (CAD). High accuracy reported in expert hands but dependent on operator training and image quality. The EVAREST study provides UK-wide data evaluate real-world performance of stress echocardiography. Methods results Participants undergoing for CAD were recruited from 31 hospitals. followed up through health records which underwent adjudication. Cardiac outcome was defined as anatomically or...
The importance of xanthine oxidase and its products is being increasingly recognized in cardiovascular medicine. Patients who have had a stroke are at high risk future events this higher those with urate levels. aim pilot study was to see if inhibiting altered arterial wave reflection, determined from the augmentation index (AIx). In double‐blind study, 30 patients (≥0.38 mmol/L) were randomized 300 mg allopurinol or placebo for 8 weeks. AIx measurements made before after treatment using...
Aims To test the hypothesis that urate predicts cardiac death after stroke independent of conventional risk factors atherosclerosis, creatinine and diuretic use.
<b>Objectives:</b> To test the hypothesis that QTc of any lead ECG predicts death after stroke, and to determine which carries greatest risk cardiac when its is measured. <b>Design:</b> Standard 12 ECGs were analysed by one observer who was blind patient outcome. <b>Setting:</b> A major teaching hospital in Scotland. <b>Patients:</b> 404 stroke survivors studied at approximately year cerebrovascular event followed for up 6.3 years. <b>Outcome measures:</b> Death from cause mortality....
We conducted a meta-analysis of the existing literature therapeutic effects using GLP-1 agonists to improve metabolism failing heart. Animal studies showed significant improvement in markers cardiac function, such as left ventricular ejection fraction (LVEF), with regular agonist infusions. In clinical trials, potential improving function were modest: LVEF improved by 4.4% compared placebo (95% C.I 1.36-7.44, P = 0.005). However, BNP levels not significantly altered heart failure. two modest...
Abstract Aims Stress echocardiography is widely used to assess patients with chest pain. The clinical value of a positive or negative test result inform on likely longer-term outcomes when applied in real-world practice across healthcare system has not been previously reported. Methods and results Five thousand five hundred three recruited 32 UK NHS hospitals between 2018 2022, participating the EVAREST/BSE-NSTEP prospective cohort study, data medical up 2023 available from England were...
To test the hypothesis that B-type natriuretic peptide (BNP) predicts reversible myocardial ischaemia in stroke survivors who do not have chest pain or previous infarction.56 (mean (SE) age 68 (8) years) underwent tetrofosmin perfusion scanning with dipyridamole as stressor. The degree of was assessed by a scoring system (out 64) an experienced observer blinded to results BNP.In whole cohort, BNP significantly correlated on stress (Spearman's r = -0.475, p < 0.001). also (stress score - rest...
Acute heart failure (AHF) hospitalisation is associated with 10% mortality. Outpatient based management (OPM) of AHF appeared effective in observational studies. We conducted a pilot randomised controlled trial (RCT) comparing OPM standard inpatient care (IPM).We patients AHF, considered to need IV diuretic treatment for ≥2 days, IPM or OPM. recorded all-cause mortality, and the number days alive out-of-hospital (DAOH). Quality life, mental well-being Hope scores were assessed. Mean NHS cost...
<b>Objectives:</b> To find out what spectrum of cardiac abnormalities are found in those stroke survivors who can be deemed to at high risk by their having long QT. <b>Methods:</b> 202 patients with good recovery from a cerebrovascular event occurring least one month previously were recruited into prospective epidemiological study. These underwent battery investigations including 12 lead ECG, echocardiography, myocardial perfusion scanning, and heart rate variability assessment. The ECGs...
<i>Background:</i> We aim to assess whether social deprivation independently predicts case fatality after a stroke patient has been admitted hospital, and affected duration of hospital stay. <i>Methods:</i> Cohort study in tertiary teaching included consecutive patients within 48 h their between 1988 1994. Outcome measures were at 1 year length The socioeconomiccategory was derived from the postcode sectorof residence for (Carstairs index). Cause death determined by...