Danshen, the dried root of Salvia miltiorrhiza Bge., is a widely used commercially available herbal drug, and unstable quality different samples current issue. This study focused on comprehensive systematic method combining fingerprints chemical identification with chemometrics for discrimination assessment Danshen samples. Twenty-five were analyzed by HPLC-PAD HPLC-MSn. Forty-nine components identified characteristic fragmentation regularities summarized further interpretation bioactive...

The internet is one of the most popular health information resources, and Chinese constitute one-fifth online users worldwide. As penetration continues to rise, more details on population seeking need be known based current literature.

Nerve growth factor (NGF) is critical in regulating the homeostasis of microglial cells. It activates various signaling pathways that mediate phosphorylation cAMP response element-binding protein (CREB) at key regulatory sites. The decrease phosphorylated CREB (p-CREB) expression linked to neuroinflammatory responses. exact molecular mechanism by which propofol regulates polarization and induces neuroinflammation via NGF/CREB axis remains unclear. This study aims investigate specific...

Objective: Stroke patients with tube feeding have a high probability of problems when they had regained oral intake ability. Assisting eating is major task for caregivers and require better training. We developed an intervention to engage caregiver in prior removal examined the impact on resumption rehabilitation among stroke survivor. Methods: A total 61 dysphagia recovery were enrolled hospital from Jan. 2021 Jul. 2024. They all recovered complete before discharge. Inclusion criteria...

Thyroid dysfunction may affect the intestinal microbiota through short-chain fatty acids (SCFAs) in marine fish. This study investigated effects of triiodothyronine (T3, 20 ng/g) and thyroxine (T4, ng/g), propylthiouracil (PTU, 5000 on growth performance, SCFA profiles, composition little yellow croakers Larimichthys polyactis. The results showed that dietary thyroid-active agent supplementation significantly decreased weight gain, specific ratio. Moreover, T3, T4, PTU induced states...

We propose a new minimum-distance estimator for linear random coefficient models. This integrates the recently advanced sliced Wasserstein distance with nearest neighbor methods, both of which enhance computational efficiency. demonstrate that proposed method is consistent in approximating true distribution. Additionally, our formulation encourages diffusion process-based algorithm, holds independent interest and potential broader applications.

Interspecific hybrid combinations of Larimichthys crocea × polyactis exhibit heterosis in terms growth traits; however, the molecular regulatory mechanism underlying this phenomenon remains unclear. DNA methylation plays a pivotal role regulating gene expression and is involved development processes. In study, we comprehensively investigated intricate processes by integrating transcriptome methylome datasets from brain, liver, muscle tissues. We analyzed total 72 sequence datasets, including...

Housefly maggot larvae (HML) have been identified as a potential alternative animal diet for the fattening process of Chinese mitten crab (Eriocheir sinensis). However, feasibility and impacts HML supplementation require further investigation. The present study evaluated effects dietary on growth indices, nutrient compositions, antioxidant activity, texture profiles edible tissues E. sinensis. results showed that effectively improved hepatic steatosis index both genders sweet amino acid...

Question-oriented text retrieval, aka natural language-based has been widely used in software engineering. Earlier work concluded that questions with the same keywords but different interrogatives (such as how, what) should result answers. But what is difference? How to identify right answers a question? In this paper, we propose investigate "answer style" of interrogatives. Towards end, build classifiers repository and re-ranking approach refine search results. The are trained by over...

Background: Global budget (GB) is considered one of the most important payment methods available. Since a new round healthcare system reforms in 2009, Chinese government has been paying attention to this prospective payment. However, it unclear whether GB influenced cost control and how works rural China.Methods: YC county was chosen as intervention group, with 33,175 inpatients before 36,883 after reform (2012 2014, respectively). ZJ acted 23,668 29,555 inpatients, respectively. The...

Continuity of care is widely considered a principle primary that decreases healthcare utilization and mortality. However, the effect continuity on health-related quality life (HRQoL) for adult patients with hypertension remains unclear.To further evaluate care, we implemented cohort study among hypertensive aged over 35 years (n = 1200) in six townships Qianjiang District, Chongqing, China, between 2012 2014. The ultimately included 1079 participants. index was calculated using claim-based...

Background: Integrated care not only could fix up the fragmental healthcare caused by ageing of population, changing disease spectrum and fast-growing medical scientific knowledge, also improve continuity quality life.Purpose/Objectives: To investigate growth pattern, languages, core journals, jurisdictions research domains integrated care.Methods: Literature search: The Medline/PubMed was searched using search strategy "(delivery health care, [MeSH Terms]) OR care" without time language...

Underwater noise pollution has become a potential threat to aquatic animals in the natural environment. The main causes of such are frequent human activities creating underwater environmental noise, including commercial shipping, offshore energy platforms, scientific exploration activities, etc. However, aquaculture environments, also an unavoidable problem due background created by equipment. Some research shown that certain fish show adaptability over period time. This could be fish’s...

Abstract Saprolegnia infections cause severe economic losses among freshwater fish farming. In this study, two known compounds, rhein and aloe‐emodin, were isolated from Rheum palmatum , the in vitro inhibitory activity of both compounds against mycelial growth spore germination was tested. Both aloe‐emodin able to decrease all tested concentrations after exposure for 48 h. Complete inhibition observed at 20 mg/L 50 while 100% prevented 16 40 respectively. Because showed stronger anti‐...

Integrative strategy of health services delivery has been proven to be effective in economically developed countries, where the healthcare systems have enough qualified primary care providers. However rural China lacks such providers act as gatekeeper, besides, Chinese hypertensive patients are usually old age, more likely exposed risk factors and they experience a greater socio-economic burden. All these setting specific features make effectiveness integrative improving related quality life...

Health insurance contributes to reducing the economic burden of disease and improving access healthcare. In 2016, Chinese government announced integration New Cooperative Medical Scheme (NCMS) Urban Resident Basic Insurance (URBMI) reduce system segmentation. Nevertheless, it was unclear whether there would be any geographic variation in health benefits if two types were integrated. The aim this study identify potential related contributing factors. This cross-sectional carried out Qianjiang...

Abstract Background The impact of retirement on physical activity among older individuals remains ambiguous. This study aims to investigate the influence and delineate trajectories changes during transition elderly Chinese residents. Additionally, we endeavor examine factors that contribute each trajectory. Methods longitudinal cohort used data from four surveys China Health Retirement Longitudinal Study included a sample 428 who underwent formal provided information activity. We employed...