A5101663105- Neurobiology and Insect Physiology Research
- Nutrition, Genetics, and Disease
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Plant biochemistry and biosynthesis
- Insect Resistance and Genetics
- Genomics and Rare Diseases
- Marine animal studies overview
- Gender Studies in Language
- Aquaculture Nutrition and Growth
- Invertebrate Immune Response Mechanisms
- Identification and Quantification in Food
- vaccines and immunoinformatics approaches
- Inflammatory Bowel Disease
- Traditional Chinese Medicine Analysis
- Biochemical and Structural Characterization
- Microbial Natural Products and Biosynthesis
- Antimicrobial Peptides and Activities
- Cancer-related gene regulation
- Growth Hormone and Insulin-like Growth Factors
- Cholinesterase and Neurodegenerative Diseases
- Dendrimers and Hyperbranched Polymers
- Aquaculture disease management and microbiota
- Physiological and biochemical adaptations
- Plant Gene Expression Analysis
Ningbo University
2016-2025
The Seventh Affiliated Hospital of Sun Yat-sen University
2024
Sun Yat-sen University
2024
ZheJiang Academy of Agricultural Sciences
2024
Institute of Hydrobiology
2024
Affiliated Hospital of Qingdao University
2021
Qingdao University
2021
Chinese Academy of Tropical Agricultural Sciences
2014
Genomics (United Kingdom)
2014
Tropical Crops Genetic Resources Institute
2014
Salvia miltiorrhiza is one of the most popular traditional medicinal herbs in Asian nations. Its dried root contains a number tanshinones, protocatechuic aldehyde, salvianolic acid B and rosmarinic, used for treatment various diseases. The finding microRNAs (miRNAs) their target genes will help understand biological role on biosynthesis tanshinones S. miltiorrhiza. In present study, total 452 known miRNAs corresponding to 589 precursor (pre-miRNAs), 40 novel 24 pre-miRNAs were identified...
Abstract Background Vedolizumab (VDZ) is a humanized monoclonal antibody, that selectively targets α4β7 integrin and approved for Crohn’s disease (CD) Ulcerative colitis (UC). Previous studies demonstrated better efficacy of VDZ in bio-naïve pts with CD, however, there lack sufficient data Chinese pts. VALUE study (NCT04872491) prospective, multicenter, single-armed observational evaluating the safety effectiveness UC CD patients (pts). Methods This subgroup second interim analysis trial was...
Underwater noise pollution has become a potential threat to aquatic animals in the natural environment. The main causes of such are frequent human activities creating underwater environmental noise, including commercial shipping, offshore energy platforms, scientific exploration activities, etc. However, aquaculture environments, also an unavoidable problem due background created by equipment. Some research shown that certain fish show adaptability over period time. This could be fish’s...
The insulin-like androgenic gland hormone (IAG) is mainly produced in the (AG) of male crustaceans, and a crucial regulator sexual differentiation. In current study, full-length cDNA IAG swimming crab, Portunus trituberculatus (Pt-IAG), was cloned characterized. Similar to other reported IAGs, deduced amino acid sequence Pt-IAG consist signal peptide, B chain, C peptide A containing 6 conserved cysteines that form two inter-chain disulfide bonds one intra-B chain bond. Tissue distribution...
The SRY-related HMG-box (Sox) family is a group of transcriptional regulators that play critical role in many important developmental processes both vertebrates and invertebrates. In aquatic animals, the function Sox genes on sexual development has been gained particular attentions. present study reported molecular characterization SoxE members (PtSoxE) swimming crab, Portunus trituberculatus, tissue distribution analysis showed it was male-specific. Since most highly expression PtSoxE found...
The problem of marine noise pollution has a long history. Strong (>120 dB re 1 µPa) will affects the growth, development, physiological responses, and behaviors fish, also can induce stress response, posing mortal threat. Although many studies have reported that underwater may affect survival fish by disturbing their nervous system endocrine system, underlying causes death due to stimulation remain unknown. Therefore, in this study, we used models conduct strong (50-125 µPa, 10-22,000 Hz)...
Blumea balsamifera DC is a member of the Compositae family and frequently used as traditional Chinese medicine.Blumea rich in monoterpenes, which possess variety pharmacological activities, such antioxidant, anti-bacteria, antiviral activities.Farnesyl diphosphate synthase (FPS) key enzyme biosynthetic pathway terpenes, playing an important regulatory role plant growth, resistance secondary metabolism.Based on conserved oligo amino acid residues published FPS genes from other higher species,...
The Sry-related HMG-box (Sox) family is a group of transcriptional regulators that play critical role in many important developmental processes both vertebrates and invertebrates. In aquatic animals, the function Sox genes on sexual development has been gained particular attentions. present study reported molecular characterization member (PtSoxE) swimming crab, Portunus trituberculatus, tissue distribution analysis showed it was male-specific. Since most highly expression PtSoxE found...
Abstract BackgroundSmall interfering RNA (siRNA) has emerged as a kind of promising therapeutic agents for cancer therapy. However, the off-target effect and degradation are main challenges siRNAs delivery. Herein, an enzyme-free DNA amplification strategy initiated by specific endogenous microRNA been developed in situ generation with enhanced gene therapy on cervical carcinoma.MethodsThis contains three hairpins (H1, H2/PS H3) which can be triggered microRNA-21 (miR-21) self-assembly...
The Sry-related HMG-box (Sox) family is a group of transcriptional regulators that play critical role in many important developmental processes both vertebrates and invertebrates. In aquatic animals, the function Sox genes on sexual development has attracted particular attention. present study reported molecular characterization member (PtSoxE) swimming crab, Portunus trituberculatus, tissue distribution analysis showed it was male-specific. Since highest expression PtSoxE found androgenic...