A5082158083- Marine Sponges and Natural Products
- Microbial Natural Products and Biosynthesis
- Synthetic Organic Chemistry Methods
- Coral and Marine Ecosystems Studies
- Synthesis and Biological Activity
- Marine Ecology and Invasive Species
- Marine Biology and Environmental Chemistry
- Marine Biology and Ecology Research
- Chemical synthesis and alkaloids
- Chemical Synthesis and Analysis
- Crustacean biology and ecology
- Synthesis and Catalytic Reactions
- Bioactive Compounds and Antitumor Agents
- Fish Biology and Ecology Studies
- Marine and coastal plant biology
- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Carbohydrate Chemistry and Synthesis
- Parasite Biology and Host Interactions
- Traditional and Medicinal Uses of Annonaceae
- Ichthyology and Marine Biology
- Cephalopods and Marine Biology
- Coleoptera Taxonomy and Distribution
- Marine Toxins and Detection Methods
- X-ray Diffraction in Crystallography
Naturalis Biodiversity Center
2015-2024
Leiden University
2024
Radboud University Nijmegen
2015
Radboud University Medical Center
2015
University of Amsterdam
2003-2014
Amsterdam Museum
2003-2012
Systematic (Netherlands)
2001-2011
The University of Tokyo
2001-2010
Kagoshima University
1998-2010
Suntory (Japan)
2007-2010
The World Register of Marine Species is an over 90% complete open-access inventory all marine species names. Here we illustrate the scale problems with names, synonyms, and their classification, describe how WoRMS publishes online quality assured information on species. Within WoRMS, 100 global, 12 regional 4 thematic databases are integrated a common taxonomy. Over 240 editors from 133 institutions 31 countries manage content. To avoid duplication effort, content exchanged 10 external...
The species of the cosmopolitan sponge genus Mycale occurring in tropical Indo-West Pacific region and adjacent subtropical waters are reviewed taxonomically. Specimens incorporated collections Naturalis Biodiversity Center form basis this comprehensive study, supplemented by (type) specimens borrowed from or examined other institutions. available numbered 351, belonging to 44 species, including 14 new science, (Aegogropila) prognatha sp.nov., (Carmia) amiri fungiaphila monomicrosclera...
The novel cyclic depsipeptides papuamides A (1), B (2), C (3), and D (4) have been isolated from Papua New Guinea collections of the sponges Theonella mirabilis swinhoei. Their structures were determined by a combination spectroscopic analysis chemical degradation derivatization studies. In addition to glycine, alanine, threonine, these peptides contain number unusual amino acids including 3,4-dimethylglutamine, β-methoxytyrosine, 3-methoxyalanine, 2,3-diaminobutanoic acid or...
The new chlorinated peptides sintokamides A to E (1−5) have been isolated from specimens of the marine sponge Dysidea sp. collected in Indonesia. Their structures were elucidated by a combination spectroscopic and single-crystal X-ray diffraction analyses. Sintokamide (1) is an inhibitor N-terminus transactivation androgen receptor prostate cancer cells.
Past taxonomic studies of Western Indian Ocean and Red Sea Calcarea have been few sporadic (e.g. Schuffner 1877, Jenkin 1908, Row 1909, Dendy 1913, 1916, Voigt et al. 2017, 2018). Nevertheless, approximately 70 species are known from these for the considered region, but descriptions older records often lack sufficient details reliable identification. We studied collection kept in Naturalis Biodiversity Center. Available specimens numbered 145, collected Sea, Seychelles, Maldives, Mayotte...
Alveospongia sinuosclera gen. nov. sp. is described from shallow-waters off Canavieiras (Bahia, Brazil). The species bears an unusual morphology, combining saccular or alveolar, evenly perforated habit, and sinuous spiny microrhabdose microscleres. This sponge tentatively classified within the Heteroxyidae Dendy (1905), on basis of its confused choanosomal architecture styles, possession Assays to generate DNA sequences this material were unsuccessful. We emended diagnosis family include...
Haplosclerid sponges possessing a unique asymmetric flagelliform type of sigmoid microsclere have been reported from all global oceans. This peculiar spicule, characterized by circular or elliptical shape, with longer and sharper curved ending at one side shorter more gradually the opposing side, is proposed to be termed ‘flagellosigma’. These invariably also possess smaller normal sigmas while their skeletal structure oxea megascleres markedly confused. They are assigned large genus...
Liphagal (1), a selective inhibitor of PI3K α, has been isolated from the marine sponge Aka coralliphaga collected in Dominica. The "liphagane" meroterpenoid carbon skeleton liphagal (1) is new. A biomimetic total synthesis used to confirm constitution and support proposed biogenesis.
A novel MMP inhibitor, ageladine (1) with antiangiogenic activity was isolated from a marine sponge Agelas nakamurai. Structure 1 determined by combination of spectroscopic and chemical methods to be an unprecedented structure 4-(4,5-dibromo-1H-pyrrol-2-yl)]-1H-imidazo[4,5-c]pyridin-2-amine.
Five new alkaloids, dictyodendrins A−E (1−5), were isolated from the Japanese marine sponge Dictyodendrilla verongiformis as telomerase inhibitors. Their structures elucidated by spectroscopic and chemical methods. Dictyodendrins are tyramine-based pyrrolocarbazole derivatives containing three or four p-hydroxybenzene groups. They inhibited completely at a concentration of 50 μg/mL.
Exiguamine A (1), a hexacyclic alkaloid with an unprecedented skeleton, has been isolated from the marine sponge Neopetrosia exigua collected in Papua New Guinea. The structure of exiguamine (1) was elucidated by combination spectroscopic analysis and single-crystal X-ray diffraction analysis. Ki 210 nM for inhibition indoleamine-2,3-dioxygenase (IDO) vitro, making it one most potent IDO inhibitors known to date. putative biogenesis new skeleton starts DOPA, tryptophan, N,N-dimethylhydantoin.
Four submersible dives off the coast of Bonaire (Caribbean Netherlands) and Klein Curaçao (Curaçao) to depths 99.5–242 m, covering lower mesophotic upper dysphotic zones, yielded 52 sponge specimens belonging 31 species. Among these we identified 13 species as new science. These are Plakinastrella stinapa n. sp., Pachastrella pacoi Characella pachastrelloides Geodia curacaoensis Caminus carmabi Discodermia adhaerens Clathria (Microciona) acarnoides Antho (Acarnia) pellita Parahigginsia...
In the 10th edition of Systema Naturae (Linnaeus, 1758), which is starting point Code for Zoological Nomenclature (ICZN Art. 3), Linnaeus named three species genus Alcyonium, A. arboreum, digitatum, and bursa. The name Alcyonium was based on 16th 17th century pre-Linnaean use a diversity marine organisms, including cnidarians, sponges, bryozoans, algae. first valid presentation name, narrowed this down to comprise two clear cnidarians (A. currently Paragorgia arborea, still accepted under...
The marine sponge Dysidea herbacea collected from Indonesia yielded four new polybrominated diphenyl ether congeners 2-5 and the known derivatives 1, 6, 7. structures of compounds were unambiguously established on basis NMR spectroscopic (1H, 13C, COSY, 1H-detected direct long-range 13C-1H correlations) mass spectrometric (EIMS) data. All active against Gram-positive bacteria Bacillus subtilis phytopathogenic fungus Cladosporium cucumerinum. isolated also in brine shrimp lethality test. In...
Analysis of the Philippine marine sponge Xestospongia ashmorica afforded four new manzamine congeners 1−4 and known compounds 5 7−9. Compound 1 is 6-deoxy derivative X, while 2−4 are N-oxides J (5), 3,4-dihydromanzamine A (6), (7), respectively. The structures were unambiguously established on basis NMR spectroscopic (1H, 13C, COSY, 1H-detected direct, long-range 13C−1H correlations) mass spectrometric (EI, FAB-MS, electrospray ionization) data. Alkaloid N-oxide confirmed by conversion to...
Sprirastrellolide A, a novel antimitotic macrolide, has been isolated from the Caribbean marine sponge Spirastrella coccinea. It 47-carbon linear polyketide backbone incorporated into highly functionalized 38-membered lactone containing tetrahydropyran and two spiro bispyran substructures embedded in macrocycle side chain terminating carboxylic acid. A's structure was elucidated by detailed spectroscopic analysis of its methyl ester 2. Spirastrellolide A 2 shows potent activity cell-based...
Massadine, a highly oxygenated alkaloid, was isolated from the marine sponge Stylissa aff. massa as an inhibitor of geranylgeranyltransferase type I (GGTase I). The structure massadine has been deduced spectral data. Massidine inhibited GGTase Candida albicans with IC(50) value 3.9 microM. [structure: see text]