Zeyu Wu

ORCID: 0000-0002-4634-0663
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • Computational Drug Discovery Methods
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Diagnosis and Treatment
  • RNA modifications and cancer
  • Gut microbiota and health
  • Gestational Diabetes Research and Management
  • Cholinesterase and Neurodegenerative Diseases
  • Cancer, Hypoxia, and Metabolism
  • Lung Cancer Research Studies
  • Drug Transport and Resistance Mechanisms
  • Ginkgo biloba and Cashew Applications
  • Colorectal and Anal Carcinomas
  • Synthesis and biological activity
  • Salivary Gland Disorders and Functions
  • Diet and metabolism studies
  • Prostate Cancer Treatment and Research
  • Advanced Wireless Communication Technologies
  • Cancer-related molecular mechanisms research
  • IoT Networks and Protocols
  • Trigeminal Neuralgia and Treatments
  • Colorectal Cancer Surgical Treatments
  • Nanoplatforms for cancer theranostics
  • Vascular Malformations Diagnosis and Treatment
  • Intracranial Aneurysms: Treatment and Complications

Hefei University of Technology
2013-2025

Second Xiangya Hospital of Central South University
2022-2025

Central South University
2019-2025

First Affiliated Hospital of Xinjiang Medical University
2020-2024

Xinjiang Medical University
2020-2024

Tianjin University of Technology
2023-2024

Zhejiang University of Technology
2024

Harbin Medical University
2024

Fourth Affiliated Hospital of Harbin Medical University
2024

Stomatology Hospital
2020-2024

An artificial nociceptor, as a critical and special bionic receptor, plays key role in bioelectronic device that detects stimuli provides warnings. However, fully exploiting applications remains major challenge due to the lack of methods implementing basic nociceptor functions nociceptive blockade single device. In this work, we developed Pt/LiSiO

10.1021/acsami.4c01406 article EN ACS Applied Materials & Interfaces 2024-04-09

Nuclear localization of the androgen receptor (AR) is necessary for its activation as a transcription factor. Defining mechanisms regulating AR nuclear in androgen-sensitive cells and how these are dysregulated castration-resistant prostate cancer (CRPC) fundamentally important clinically relevant. According to classical model intracellular trafficking, androgens induce import withdrawal causes export. The present study has led an updated that could be imported absence androgens,...

10.1172/jci141335 article EN Journal of Clinical Investigation 2020-12-17

Hypoxia-inducible factor-1α (HIF-1α) and its downstream factor, 19 kDa BCL-2 interacting protein 3 (BNIP3), promote cellular autophagy under hypoxic conditions. However, their roles in pulpitis are unclear. Therefore, the changes inflammatory response levels caused by hypoxia during were evaluated. Additionally, regulatory mechanism of HIF-1α/BNIP3 was explored.

10.1016/j.archoralbio.2024.105881 article EN cc-by-nc-nd Archives of Oral Biology 2024-01-05

Percutaneous transthoracic puncture of small pulmonary nodules is technically challenging. We developed a novel electromagnetic navigation system for the sub-centimeter lung by combining multiple deep learning models with and spatial localization technologies. compared performance DL-EMNS conventional CT-guided methods in percutaneous punctures using phantom animal models. In study, group showed higher technical success rate (95.6% vs. 77.8%, p = 0.027), smaller error (1.47 ± 1.62 mm 3.98...

10.1038/s41598-025-85209-6 article EN cc-by-nc-nd Scientific Reports 2025-01-20

The ever-increasing global prevalence of obesity has trended towards a younger age. ecological characteristics and changes the oral gut microbial community during childhood are poorly understood.In this study, we analyzed salivary fecal microbiota 30 children with normal weight aged 3-5 years via third-generation long-range DNA sequencing,with aim understanding structure identifying specific lineages genera in that may be associated obesity.The results revealed significant variation alpha...

10.3389/fcimb.2023.1102650 article EN cc-by Frontiers in Cellular and Infection Microbiology 2023-03-29

Abstract Achieving photothermal therapy (PTT) at ultralow laser power density is crucial for minimizing photo‐damage and allowing higher maximum permissible skin exposure. However, this requires agents to possess not just superior conversion efficiency (PCE), but also exceptional near‐infrared (NIR) absorptivity. J ‐aggregates, exhibit a significant redshift narrower absorption peak with extinction coefficient. Nevertheless, achieving predictable ‐aggregates through molecular design remains...

10.1002/ange.202319875 article EN Angewandte Chemie 2024-01-16

Plant tissue regeneration is critical for genetic transformation and genome editing techniques. During the process, changes in epigenetic modifications accompany cell fate transition. However, how allele-specific DNA methylation two haplotypes contributes to transcriptional dynamics during remains elusive. Here we applied an inter-species hybrid poplar (

10.1093/hr/uhae027 article EN cc-by Horticulture Research 2024-01-24

Abstract Objective Brusatol (BT) is a quassinoid compound extracted from Brucea javanica that traditional Chinese herbal medicine. possesses biological and medical activity, including antitumor, antileukemia, anti-inflammatory, antitrypanosomal, antimalarial, antitobacco mosaic virus activity. To summarize discuss the antitumor effects of BT its mechanisms actions, we compiled this review by combining extensive relevant literature our previous studies. Methods We searched retrieved papers...

10.1093/jpp/rgae017 article EN cc-by-nc Journal of Pharmacy and Pharmacology 2024-02-07

Given the widespread clinical demand, addressing irregular cranial bone defects poses a significant challenge following surgical procedures and traumatic events. In situ-formed injectable hydrogels are attractive for due to their ease of administration ability incorporate ceramics, ions, proteins into hydrogel. this study, multifunctional hydrogel composed oxidized sodium alginate (OSA)-grafted dopamine (DO), carboxymethyl chitosan (CMCS), calcium ions (Ca2+), nanohydroxyapatite (nHA),...

10.1021/acsami.4c07057 article EN ACS Applied Materials & Interfaces 2024-07-19

Dental erosion is a chemical-mechanical process that leads to the loss of dental hard tissues. This study aimed investigate effect pomegranate juice on enamel.

10.1371/journal.pone.0298404 article EN cc-by PLoS ONE 2024-04-10

Persephin (PSPN) is one of the neurotrophic factors glial cell line-derived factor (GDNF) family ligands (GFLs) which have been found to promote survival specific populations neurons. The aim this study was assess potential therapeutic function gene-modified mesenchymal stem cells (MSCs)-Lv-PSPN-MSCs in 6-OHDA-induced Parkinson’s disease (PD) rats models. Here, we worked on isolation, purification, identification and amplification MSCs vitro. expression analysis revealed that several neural...

10.1371/journal.pone.0105118 article EN cc-by PLoS ONE 2014-08-13

Abstract Objective: To determine the levels of s-IgA in saliva caries patients and healthy controls, to evaluate whether there is a correlation between it by meta-analysis. Methods: The PubMed, MEDLINE, EMBASE, Web Science, Cochrane Library, Scopus, Chinese National Knowledge Infrastructure, Wanfang Data, Chongqing VIP database for Technical Periodicals, China BioMedical Literature Services System databases were searched initially April 2020 repeated August 2020. Two independent evaluators...

10.1042/bsr20203208 article EN cc-by Bioscience Reports 2020-12-01

Abstract Peri-implants is a chronic disease leads to the bone resorption and loss of implants. Polygoni Cuspidati Rhizoma (PCRER), traditional Chinese herbal has been used treat diseases metabolism. However, its mechanism anti-bone absorption still remains unknown. We aimed identify molecular target involved in PCRER potential treatment theory by network pharmacology. The active ingredients disease-related targets were retrieved from TCMSP, Swiss Target Prediction, SEA databases then...

10.1038/s41598-022-12366-3 article EN cc-by Scientific Reports 2022-05-17
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