A5008326293- Inflammatory Bowel Disease
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Diverticular Disease and Complications
- Microscopic Colitis
- Esophageal and GI Pathology
- Colorectal Cancer Surgical Treatments
- Clusterin in disease pathology
- Esophageal Cancer Research and Treatment
- Cancer, Lipids, and Metabolism
- TGF-β signaling in diseases
- Tuberculosis Research and Epidemiology
- Colorectal and Anal Carcinomas
- Helicobacter pylori-related gastroenterology studies
- Cancer, Hypoxia, and Metabolism
- Pharmacological Effects of Natural Compounds
- Gastrointestinal Tumor Research and Treatment
- Gut microbiota and health
- Gastrointestinal Bleeding Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Genetic factors in colorectal cancer
Okayama University
2013-2025
Okayama University Hospital
2019-2024
National Hospital Organization
2019
Kagawa Prefectural Central Hospital
2018
Leucine-rich alpha 2 glycoprotein (LRG) is one of the serum biomarkers for disease activity ulcerative colitis (UC). We focused on correlation between changes LRG and endoscopic histologic UC, in comparison to fecal calprotectin (Fcal), immunochemical test (FIT), C-reactive protein (CRP). Seventy-nine patients with two or more colonoscopies were enrolled, 123 paired 121 biopsies examined. With regard change endoscopic/histologic preceding subsequent colonoscopy, there was improvement (n =...
Objectives: Aggressive colorectal cancer (CRC) frequently originates from serrated lesions (SLs), particularly in the proximal colon, which are challenging to detect using standard screening colonoscopy. Although duplicate examinations or chromocolonoscopies recommended for detecting SLs, evidence randomized trials is limited. We evaluated effectiveness of tandem colonoscopy with an acetic acid-indigo carmine mixture (AIM) SLs colon compared white-light imaging (WLI) and indigo (IC)....
Oral tacrolimus is an effective treatment for refractory ulcerative colitis (UC). However, underutilized because of the difficulties in transitioning to subsequent maintenance therapy and concerns about adverse events. We evaluated clinical outcomes, events, accumulated medication costs consecutive 72 UC patients treated with tacrolimus. Fifty-five (76%) pancolitis 43 (60%) acute severe disease were entered. Fifty-four (75%) achieved remission 8 weeks after starting At last visit, 62 (86%)...
Background and Aims The submucosal injection solution is used to assist in endoscopic surgery. high viscosity of current solutions makes it difficult inject. In the present study, we developed an extremely low-viscosity, easy-to-use using phosphorylated pullulan (PPL). Methods PPL were prepared at different concentrations, their was measured. mucosal elevation capacity evaluated excised porcine stomachs. Controls included 0.4% sodium hyaluronate (SH), 0.6% alginate (SA), saline. To evaluate...
Abstract Background and Aim Follistatin ( FST ) is a glycoprotein expressed in most organs, which interacts with activins or other members of the transforming growth factor beta family. Recently, several reports have shown that regulates variety processes during tumor progression. Here, serum patients liver diseases was measured, its clinical utility as biomarker assessed. Methods Serum collected from 162 (91 hepatocellular carcinoma [ HCC ], 43 cirrhosis, 28 chronic hepatitis) well 16...
This study examined the utility of combined use transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS FIT were retrospectively enrolled. For TUS, colon was divided into five segments, bowel wall thickness measured evaluated. The accuracy (> 100 ng/ml) detecting inflammation (MES>0) 0.93, whereas that (BWT>2 mm) each segment...
Salvage therapy for esophageal cancer following chemo-radiation (CRT) has not been established. We aimed to evaluate endoscopic submucosal dissection (ESD) as a salvage based on histopathological features of lesions. compared 10 lesions in eight patients with local residual, recurrent, or metachronous squamous cell carcinoma treated by ESD after CRT (CRT group) and 59 without (non-CRT during the same period. The en bloc resection rate was 100 % while complete 80.0 CRT, indicating no...
<title>Abstract</title> Leucine-rich alpha 2 glycoprotein (LRG) is one of the promising serum biomarkers for disease activity ulcerative colitis (UC). However, several previous reports suggested that correlation absolute values LRG with endoscopic/histologic was superior to CRP but inferior those fecal markers. Here, we focused on between changes and endoscopic histologic UC, in comparison calprotectin (Fcal), immunochemical test (FIT), C-reactive protein (CRP). Patients UC who underwent two...
Cold snare polypectomy (CSP) and underwater endoscopic mucosal resection (UEMR) have been developed recently, in addition to conventional methods, but adverse events of each method not fully clarified. We compared the outcomes for appropriate choice.
<title>Abstract</title> Oral tacrolimus is an effective treatment for refractory ulcerative colitis (UC). However, underutilized because of the difficulties in transitioning to subsequent maintenance therapy and concerns about adverse events. We evaluated clinical outcomes, events, accumulated medication costs consecutive 72 UC patients treated with tacrolimus. Fifty-five (76%) pancolitis 43 (60%) acute severe disease were entered. Fifty-four (75%) achieved remission 8 weeks after starting...
Oral tacrolimus therapy is an effective induction for the remission of severe ulcerative colitis (UC), but it usually takes about 1 week to reach therapeutic window. We evaluated additional value cytapheresis oral in patients with UC. retrospectively 31 consecutive UC (Mayo score = 11, 12) who received from April 2010 June 2017 and were followed up 120 days or longer. Three out biologics (anti-tumour necrosis factor agents) before after initiation excluded. Patients divided into two groups...