A5072275877- Anesthesia and Pain Management
- Nausea and vomiting management
- Inflammatory Bowel Disease
- Spine and Intervertebral Disc Pathology
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Shoulder Injury and Treatment
- Microscopic Colitis
- Advanced Radiotherapy Techniques
- Gastrointestinal Tumor Research and Treatment
- Anesthesia and Sedative Agents
- Vasculitis and related conditions
- Radiation Dose and Imaging
- Genetic factors in colorectal cancer
- Colorectal Cancer Surgical Treatments
- Diverticular Disease and Complications
- Gastrointestinal Bleeding Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Acute Lymphoblastic Leukemia research
- Myofascial pain diagnosis and treatment
- Enhanced Recovery After Surgery
- Pericarditis and Cardiac Tamponade
- Spinal Hematomas and Complications
- Alcoholism and Thiamine Deficiency
- IgG4-Related and Inflammatory Diseases
Okayama University
2023-2025
Okayama University Hospital
2024-2025
Tokyo Women's College of Physical Education
2023
Kagawa Prefectural Central Hospital
2018-2023
Shimane University
2019-2021
Shizuoka Cancer Center
2021
Shimane University Hospital
2019
University of Hyogo
2016
Tokyo Metropolitan Hiroo Hospital
2015
Grodno State Medical University
2015
Leucine-rich alpha 2 glycoprotein (LRG) is one of the serum biomarkers for disease activity ulcerative colitis (UC). We focused on correlation between changes LRG and endoscopic histologic UC, in comparison to fecal calprotectin (Fcal), immunochemical test (FIT), C-reactive protein (CRP). Seventy-nine patients with two or more colonoscopies were enrolled, 123 paired 121 biopsies examined. With regard change endoscopic/histologic preceding subsequent colonoscopy, there was improvement (n =...
Oral tacrolimus is an effective treatment for refractory ulcerative colitis (UC). However, underutilized because of the difficulties in transitioning to subsequent maintenance therapy and concerns about adverse events. We evaluated clinical outcomes, events, accumulated medication costs consecutive 72 UC patients treated with tacrolimus. Fifty-five (76%) pancolitis 43 (60%) acute severe disease were entered. Fifty-four (75%) achieved remission 8 weeks after starting At last visit, 62 (86%)...
Objectives Sessile serrated lesions (SSLs) pose a risk of carcinoma, necessitating endoscopic resection. Conventional mucosal resection (EMR) often fails to achieve complete for intermediate‐sized SSLs. Although underwater EMR (UEMR) is being increasingly used colon polyps, its efficacy SSLs remains unclear. This study evaluated the rate UEMR Methods prospective, single‐arm, observational was conducted at two institutions. Patients with endoscopically diagnosed (10–20 mm) were enrolled....
Remodelling of the extracellular matrix (ECM) plays an important role in production arrhythmogenic substrate for atrial fibrillation (AF), and is considered to be promoted by connective tissue growth factor (CTGF).Our objective was assess relationship between CTGF ECM synthesis, effect olmesartan on these processes. Methods resultsFifteen canine AF models were produced rapid stimulation.They divided into three groups: pacing control (n ¼ 5): 6-week pacing, + with (2 mg/kg/day), nonpacing...
Clinical characteristics and prognosis of patients with a solitary Peutz-Jeghers polyp (PJP) have not been fully investigated.Solitary PJP was diagnosed when single hamartomatous lesion identified in the gastrointestinal tract without mucocutaneous pigmentation or family history syndrome. We retrospectively reviewed 51 (32 men 19 women) analyzed sex, age at diagnosis, endoscopic features, outcomes this patient group. The STK11/LKB1 germline mutation investigated any patients.The mean 66.1...
Background Despite the popularity of continuous thoracic paravertebral block (TPVB), there is a paucity information on catheter tip position and distribution injectate through catheter. We observed, in real time, spread dye, sensory levels produced with three different (intercostal (IC), transverse process sagittal (TS) paralaminar (PL)) approaches to ultrasound-guided TPVB patients undergoing video-assisted thoracoscopic surgery. Methods After induction general anesthesia, was conducted...
The posterior transversus abdominis plane block (TAPB) and quadratus lumborum (QLB) were developed for postoperative pain control after lower abdominal surgery. However, there is little data regarding their effects. Their analgesic effects the distribution of cutaneous sensory blockade observed in patients undergoing laparoscopic gynecologic surgery.After an induction general anesthesia, alternately received bilateral ultrasound-guided QLB type 2 (QLB2) or TAPB using 20 ml 0.375%...
Salvage therapy for esophageal cancer following chemo-radiation (CRT) has not been established. We aimed to evaluate endoscopic submucosal dissection (ESD) as a salvage based on histopathological features of lesions. compared 10 lesions in eight patients with local residual, recurrent, or metachronous squamous cell carcinoma treated by ESD after CRT (CRT group) and 59 without (non-CRT during the same period. The en bloc resection rate was 100 % while complete 80.0 CRT, indicating no...
Abstract Background Serum anti-proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA) is a disease-specific against granulomatosis with polyangiitis. PR3-ANCA useful serological marker for disease severity in ulcerative colitis (UC). The purpose of this study was to investigate whether levels could also predict the success induction therapy and compare its performance other markers, including serum CRP fecal hemoglobin. Methods This multicenter retrospective study. In total, 159...
This study examined the utility of combined use transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS FIT were retrospectively enrolled. For TUS, colon was divided into five segments, bowel wall thickness measured evaluated. The accuracy (> 100 ng/ml) detecting inflammation (MES>0) 0.93, whereas that (BWT>2 mm) each segment...
Abstract Background Accurate diagnosis of the lateral extent early gastric cancer during endoscopic submucosal dissection (ESD) is crucial to achieve negative resection margins. Similar intraoperative consultation with a frozen section in surgery, rapid forceps biopsy may be useful assessing tumor margins ESD. This study aimed evaluate diagnostic accuracy biopsy. Methods We prospectively enrolled 32 patients undergoing ESD for cancer. Biopsy samples sections were randomly collected from...
Thoracic paravertebral block (TPVB) is an established analgesic technique for breast surgery although it technically challenging. Erector spinae plane (ESPB) requires less technical expertise and may be alternative to TPVB. However, whether ESPB has similar effects TPVB still inconclusive. Moreover, information on sensory blockade of scarce. Accordingly, we conducted this retrospective propensity-matched study see if could provide comparable in patients undergoing surgery. We also compared...
Biotin is a water-soluble vitamin that functions as cofactor for biotin-dependent carboxylases. The biochemical and physiological roles of biotin in brain regions have not yet been investigated sufficiently vivo. Thus, order to clarify the function brain, we herein examined contents, biotinylated protein expression (e.g. holocarboxylases), biotin-related gene biotin-deficient rats. Three-week-old male Wistar rats were divided into control group, pair-fed group. Rats fed experimental diets...
Abstract We aimed to develop a brief, preclinical test screen the reduced hippocampal volume that is marker of early dementia [Cognitive Quotient (CQ) test]. performed an observational study adult subjects who underwent brain MRI in seven institutions from February 2018 May 2019. The CQ consists five components: (1) digits forward, (2) backward, (3) Stroop test, (4) simple calculation, and (5) mental rotation. primary outcome measure was volume. separated data into derivation (n = 322)...
<title>Abstract</title> Leucine-rich alpha 2 glycoprotein (LRG) is one of the promising serum biomarkers for disease activity ulcerative colitis (UC). However, several previous reports suggested that correlation absolute values LRG with endoscopic/histologic was superior to CRP but inferior those fecal markers. Here, we focused on between changes and endoscopic histologic UC, in comparison calprotectin (Fcal), immunochemical test (FIT), C-reactive protein (CRP). Patients UC who underwent two...
Cold snare polypectomy (CSP) and underwater endoscopic mucosal resection (UEMR) have been developed recently, in addition to conventional methods, but adverse events of each method not fully clarified. We compared the outcomes for appropriate choice.
<title>Abstract</title> Background Serum C-reactive protein (CRP), leucine-rich alpha-2 glycoprotein (LRG), and fecal calprotectin (Fcal) are non-invasive markers used to diagnose the severity of Crohn’s disease (CD). However, accuracy these is not satisfactory, most previous reports have evaluated efficacy each marker individually. We aimed improve diagnostic performance endoscopic remission (ER) CD by using a combination 3 markers. Methods tested ability various combinations for in 230...
Abstract Background Anterior cruciate ligament (ACL) reconstruction is an invasive surgical procedure for the knee. Quadruple nerve blocks including continuous femoral block and single-injection sciatic, obturator, lateral cutaneous can provide effective intraoperative anesthesia analgesia in early postoperative period. However, severe pain often appears after effect of resolves that why we conducted two studies. The first study was to determine whether dexamethasone administered along with...
硬膜外鎮痛法は，さまざまな胸腹部外科手術の周術期疼痛管理において最も一般的に使用されてきた．しかし，外科手術の低侵襲化や予防的抗凝固療法の普及により，いくつかの超音波ガイド下末梢神経ブロックが開発され硬膜外ブロックに代わって選択されるようになってきた．各ブロック法の手技が比較的簡単であることから人気を博しているが，得られる鎮痛効果の範囲が限局的であることや効果持続時間が短いなどの問題がある．正しいブロック法の選択が必要であるとともに持続注入法の確立が望まれる．本稿では，胸腹壁の解剖，各神経ブロックのテクニック，利点および問題点について述べた．