A5082473336- Thyroid Cancer Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Trauma and Emergency Care Studies
- Thyroid and Parathyroid Surgery
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Global Cancer Incidence and Screening
- Salivary Gland Tumors Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Nanoplatforms for cancer theranostics
- BRCA gene mutations in cancer
- Radiomics and Machine Learning in Medical Imaging
- Ultrasound in Clinical Applications
- COVID-19 Clinical Research Studies
- Cancer, Hypoxia, and Metabolism
- Adrenal and Paraganglionic Tumors
- Glioma Diagnosis and Treatment
- Advances in Oncology and Radiotherapy
- Hepatocellular Carcinoma Treatment and Prognosis
- Surgical site infection prevention
- Radiation Dose and Imaging
- Sulfur Compounds in Biology
- Redox biology and oxidative stress
- Pituitary Gland Disorders and Treatments
- Hedgehog Signaling Pathway Studies
University Medical Center Groningen
2016-2024
University of Groningen
2016-2023
Medisch Centrum Leeuwarden
2022
Royal North Shore Hospital
2021
Northern Sydney Local Health District
2021
The University of Sydney
2019-2021
Institut de Virologie
2021
Royal Brisbane and Women's Hospital
2021
University of Liverpool
2021
Society of Surgical Oncology
2021
BackgroundA direct comparison of severe acute respiratory syndrome coronavirus 2 positive patients with a negative control group undergoing an operative intervention during the current pandemic is lacking, and reliable estimate assumed difference in morbidity mortality between both patient categories remains unknown.MethodsWe included all consecutive confirmed pre- or postoperative status (operated 27 hospitals) 4 emergency elective operations. A propensity score-matched clinical outcomes...
Tumor-positive resection margins are present in up to 23% of head and neck cancer (HNC) surgeries, as intraoperative techniques for real-time evaluation the lacking.In this study, we investigated safety potential clinical value fluorescence-guided imaging (FGI) margin HNC patients.We determined optimal cetuximab-800CW dose by quantification intrinsic fluorescence values using multi-diameter single-fiber reflectance, (MDSFR/SFF) spectroscopy.Methods: Five cohorts three patients received...
Abstract Purpose Multifocal disease in PTC is associated with an increased recurrence rate. (MD) underdiagnosed the current gold standard of pre-operative ultrasound staging. Here, we evaluate use EMI-137 targeted molecular fluorescence-guided imaging (MFGI) and spectroscopy as a tool for intra-operative detection uni- multifocal papillary thyroid cancer (PTC) aiming to improve staging treatment selection. Methods A phase-1 study (NCT03470259) was conducted possibility detecting using MFGI...
Patients undergoing prophylactic central compartment dissection (PCLND) for papillary thyroid cancer (PTC) are often overtreated. This study aimed to determine if molecular fluorescence-guided imaging (MFGI) and spectroscopy can be useful detecting PTC nodal metastases (NM) identify negative compartments intraoperatively.We used a data-driven prioritization strategy based on transcriptomic profiles of 97 primary PTCs 80 normal tissues (NTT) tumor-specific antigens clinically available...
Object Accurate placement of the leads is crucial in deep brain stimulation (DBS). To optimize surgical positioning lead, a combination anatomical targeting on MRI, electrophysiological mapping, and clinical testing applied during procedure. Electrophysiological mapping usually done with microelectrode recording (MER), but relatively undocumented semimicroelectrode (SMER) competing alternative. In this study added value safety SMER for optimal lead insertion subthalamic nucleus (STN)...