A5067141609- Environmental and Agricultural Sciences
- Aeolian processes and effects
- Remote Sensing and Land Use
- Atmospheric aerosols and clouds
- Traditional Chinese Medicine Studies
- Cryospheric studies and observations
- Neurological Disease Mechanisms and Treatments
- Healthcare and Venom Research
- Hydrology and Watershed Management Studies
- Acupuncture Treatment Research Studies
- Environmental Changes in China
- Climate change and permafrost
- Atmospheric chemistry and aerosols
- Genomics, phytochemicals, and oxidative stress
- Forest, Soil, and Plant Ecology in China
- Climate variability and models
- Water Systems and Optimization
- Rangeland Management and Livestock Ecology
- Facial Nerve Paralysis Treatment and Research
- Epoxy Resin Curing Processes
- Synthesis and properties of polymers
- Medical Research and Treatments
- Plant Ecology and Soil Science
- Optical Systems and Laser Technology
- Groundwater flow and contamination studies
Xinjiang Institute of Ecology and Geography
2009-2025
Third Xiangya Hospital
2025
Central South University
2025
Wenzhou Medical University
2021-2024
First Affiliated Hospital of Wenzhou Medical University
2021-2024
Wuhan University
2024
Shenzhen Institutes of Advanced Technology
2022-2024
Chinese Academy of Sciences
2001-2024
University of Science and Technology of China
1999-2023
Second Military Medical University
2014-2023
Semantic concept hierarchy is still under-explored for semantic segmentation due to the inefficiency and complicated optimization of incorporating structural inference into dense prediction. This lack modeling correlations also makes prior works must tune highly-specified models each task label discrepancy across datasets. It severely limits generalization capability open set vocabulary annotation utilization. In this paper, we propose a Dynamic-Structured Propagation Network (DSSPN) that...
Cannabidiol (CBD), a phytochemical derived from Cannabis sativa L., has been demonstrated to exhibit promising anti-tumor properties in multiple cancer types. However, the effects of CBD on hepatocellular carcinoma (HCC) cells remain unknown. We have shown that effectively suppresses HCC cell growth vivo and vitro , induced pyroptosis caspase-3/GSDME-dependent manner. further accumulation integrative stress response (ISR) mitochondrial may contribute initiation pyroptotic signaling by CBD....
As inorganic rigid waterproof materials with excellent substrate compatibility, non-toxicity, harmless, and deep penetration depth, cementitious capillary crystalline (CCCW) hold great potential for application in concrete structures. However, the formulations of commercially available CCCW are currently undisclosed, hindering mechanism study CCCW, which is not conducive to development more efficient cost-effective materials. In this study, a new formulation active chemicals was developed,...
The ability to predict clinical safety based on chemical structures is becoming an increasingly important part of regulatory decision making. (Quantitative) structure–activity relationship ((Q)SAR) models are currently used evaluate late-arising concerns and possible nonclinical effects a drug its related compounds when adequate data absent or equivocal. Regulatory use will likely increase with the standardization analytical approaches, more complete reliable collection methods, better...
In the past tens of years, power conversion efficiency Cu(In,Ga)Se2 (CIGS) has continuously improved and been one fastest growing photovoltaic technologies that can also help us achieve goal carbon emissions reduction. There are several key progresses for its success, The alkali element post-deposition treatment (AlK PDT) is regarded as most important finding in last 10 which led to improvement CIGS solar cell from 20.4% 23.35%. A profound understanding influence on chemical electrical...
Abstract Background Ribosomal RNA processing protein 15 (RRP15) has been found to regulate the progression of hepatocellular carcinoma (HCC). Nevertheless, extent which it contributes spread HCC cells remains uncertain. Thus, objective this research was assess biological function RRP15 in migration HCC. Methods The expression tissue microarray (TMA), tumor tissues and cell lines were determined. In vitro, effects knockdown on migration, invasion adhesion ability assessed by wound healing...
Snowmelt from the Tianshan Mountains (TS) is a major contributor to water resources of Central Asian region. Thus, changes in snow phenology over TS have significant implications for regional supplies and ecosystem services. However, characteristics their influences on climate are poorly understood throughout entire due lack situ observations, limitations optical remote sensing clouds, decentralized political landscapes. Using passive microwave data 1979 2016 across TS, this study...
Constipation is one of the most common non-motor symptoms in patients with Parkinson's disease (PD), which could manifest during early stage disease. However, etiology constipation PD remains largely unknown. Previous studies supported that gastrointestinal dysfunction may be associated functional connectivity alterations paraventricular hypothalamic nucleus (PVN). Therefore, this study aimed to investigate potential contribution PVN pathogenesis a cohort early-stage and compare brain...
ABSTRACT In an era of rapid environmental change, accurately modeling aquatic ecosystems, particularly the lateral water flow through soil and permafrost, remains a pressing need. This study addresses this Water Energy Transfer Process (WEP) model. The WEP model overcomes limitations previous models plays crucial role in estimating groundwater basin. study, we use our new formula for calculating at permafrost depth deep percolation to subsurface, over flows cold 52 years (1970–2021). model's...
Hyperactivation of the Wnt/β-catenin signaling pathway has been widely recognized as a pathogenic mechanism for colorectal cancer (CRC). Based on previously reported lead compound, iCRT14, series 2,4-thiazolidinedione derivatives were designed, synthesized, and evaluated in vitro their antiproliferative activity against colon cells. Compound 15k exhibited most potent HCT116 SW480 cell lines. inhibited by disrupting protein-protein interactions between β-catenin TCF4. simultaneously tubulin...
Extreme climate events significantly impact vegetation ecosystems in dry regions, particularly areas adjacent to the northern foothills of Yinshan Mountain (NYSM). However, there remains limited understanding how responds such events. Analyzing response regions drought is beneficial for protection and restoration ecosystem. This study analyzes spatiotemporal variation characteristics extreme NDVI. By employing correlation analysis geographic detectors, it explores NDVI The findings indicate...
The China–Mongolia arid region adjacent to the Altai Mountain (CMA) has a sensitive ecosystem that relies heavily on both terrestrial water (TWS) and groundwater storage (GWS). However, during 2003–2016 period, CMA experienced significant glacier retreat, lake shrinkage grassland degradation. To illuminate TWS GWS dynamics in dominant driving factors, we employed high-resolution (0.1◦) GRACE (Gravity Recovery Climate Experiment) data generated through random forest (RF) combined with...
As one of the most effective traffic demand management opinions, congestion pricing can reduce private car travel and associated carbon dioxide emissions. First, we summarized status quo transport emission charges pricing, then, analyzed characteristics urban Then, proposed a (pricing) framework in which costs would be considered as part generalized cost travel. Based on this framework, paper developed bi-level mathematical model to optimize consumer surplus, using control variables. A...
Abstract The spatial and temporal variations of precipitation in the desert region China (DRC) from 1951 to 2005 were investigated using a rotated empirical orthogonal function (REOF), concentration index (PCI) Mann–Kendall trend test method (M‐K method). In addition, association between variation patterns large‐scale circulation also explored National Centers for Environmental Prediction/National Center Atmospheric Research (NCEP/NCAR) reanalysis data. results indicated that pattern was...
Serotonin (5-HT) and inflammation are 2 major hypotheses in schizophrenia (SZ) pathogenesis, both of which involve platelets. However, the association between platelet SZ has not been well studied. The aim this study was to evaluate changes count (PLT), mean volume (MPV), platelet-large cell ratio (P-LCR), distribution width (PDW), plateletcrit (PCT) patients with first-episode (FES). Meanwhile, 3 markers, including neutrophil-lymphocyte (NLR), platelet-lymphocyte (PLR), monocyte-lymphocyte...
Dimethyl fumarate (DMF) is an approved drug used in the treatment of multiple sclerosis (MS) and psoriasis therapy. Multiple studies have demonstrated other pharmacological activities DMF such as anti-cancer agent. In particular, shown that can modulate NRF2/HO1/NQO1 antioxidant signal pathway inactivate NF-κB to suppress growth colon breast cancer cells, induce cell death. this study, we aimed evaluate anti-tumor pancreatic (PC) focusing on death predominant mechanism response. We showed...
Alkali-activated slag cement (AASC) has shown immense potential for application as a low-carbon and eco-friendly cementitious material. It's crucial to modify the AASC with superhydrophobic property obtain excellent durability performance. In this paper, low-cost non-toxic stearic acid (SA) is selected hydrophobic agent impart integral alkali-activated Portland mortar (AAPSCM). The SA-modified AAPSCM (M-AAPSCM) shows superhydrophobicity contact angle of 150.6° sliding 9.5°, even when...