Sleep duration and physical activity (PA) are critical factors influencing mortality risk. However, the interaction between sleep PA with risk among cancer survivors has not been well explored. This cross-sectional study utilized data from National Health Nutrition Examination Survey (NHANES) spanning 2007-2018. Multivariable Cox regression analysis restricted cubic splines were employed to evaluate hazard ratios (HRs) 95% confidence intervals (CIs) of association in survivors....

The leukemia affects not only the quality of life (QOL) patients with disease but also that their family caregivers (FCs). research studies on QOL FCs for are limited. This study aimed to evaluate in Heilongjiang province, China.A cross-sectional questionnaire survey was undertaken 309 recruited from three hospitals province. participants assessed using Chinese version WHOQOL-BREF. Multivariate regression models were established determine predictors FCs, including socio-economic...

Objective Renal tubular damage, a pivotal pathological feature of chronic kidney disease (CKD), predicts progression. While extreme nighttime sleep duration is linked to glomerular injury by prior studies, its impact on damage remains unclear. Given that 7–9 h per night widely recommended for maintaining overall health, this study aimed assess whether long associated with renal using both observational and genetic evidence.

Abstract Centrosome number is tightly controlled during the cell cycle to ensure proper spindle assembly and division. However, underlying mechanism that controls centrosome remains largely unclear. We show herein DNA replication licensing factor Cdc6 recruited proximal side of centrioles via cyclin A negatively regulate duplication by binding inhibiting cartwheel protein Sas-6 from forming a stable complex with another centriole core protein, STIL. further demonstrate colocalizes Plk4 at...

Pericarpium citri reticulatae (PCR) has been used as a food and spice for many years is known its rich nutritional content unique aroma. However, price increases are often accompanied by adulteration. In this study, two kinds of adulterants (Orange peel-OP Mandarin Rind-MR) were identified chromaticity analysis, FT-NIR machine learning algorithm, the doping concentration was predicted quantitatively. The results show that colorimetric analysis cannot completely differentiate between PCR...

Some nuclear proteins crucial in interphase relocate to other places during the G2-M phase transition take their mitotic functions. However, how they perform these functions and underlying mechanisms remain largely unknown. Here we report that a fraction of periphery lamin-A/C, LAP2α BAF1 spindle cell cortex mitosis. RNAi knockdown induces short fluffy formation disconnection with cortex. Disrupting microtubule assembly leads accumulation cortex, whereas depolymerizing actin microfilaments...

Context: BAG3 plays a regulatory role in number of cellular processes. Recent studies have attracted much attention on its activation selective autophagy. In addition, we very recently reported that is implicated BECN1-independent autophagy, namely noncanonical Objective: The current study aimed to investigate the potential involvement canonical autophagy triggered by Earle's Balanced Salt Solution (EBSS) starvation. Setting and Design: Replacement complete medium with EBSS was used trigger...

Abstract Zhi‐zi‐chi decoction (ZZCD) is a classical formula widely used in Chinese clinical application. In the present study, novel and efficient strategy has been developed for screening identification of multiple constituents their metabolites ZZCD using ultra‐high‐performance liquid chromatography combined with triple time‐of‐flight mass spectrometry. The approach an online data acquisition method dependent on defect filter dynamic background subtraction processing techniques. First,...

Library of a university considered as an important entity and employees the library have key role to play in disseminating knowledge academic clientele university. This study conducted comprehensively investigate job satisfaction main objective followed by identifying factors finally provide suggestions overcome dissatisfaction level jobs staff serving respective universities. Study sample comprised with 510 respondents representing all professional, para-professional support categories...

Studies have shown that status-based rankings exist within almost every human social group and influence most aspects of organizational life. However, few studies discussed the relationship between employees' status citizenship behaviors (OCBs). Based on cognitive theory, this paper explores perception two types OCBs: challenging affiliative, as well mechanism underlying by introducing work vitality mediator dominance motivation moderator.We collected empirical data from different...

Purpose The purpose of this study was to investigate the participants' attitudes toward ethical issues caused by collecting social media data (SMD) for research, as well effects familiarity, trust and altruism on ethics SMD research. It is hoped that through study, scholars will be reminded respect participants engage in reflection when using Design/methodology/approach This adopted users its research subjects used Sina Microblog, world's largest Chinese platform, example. Based 320 valid...

Purpose This paper explains the formation of government resistance to open data based on cognition stakeholders in Chinese context. Design/methodology/approach Adopting grounded theory, this study interviewed 22 collect data. Through continuous coding, identified main categories and then constructed theoretical models. Findings explained five that relate resistance: practice, perception, organizational culture, motivation strategies. Then, a framework was developed conceptualizes government'...

Furniture is one of the most enduring items that children grow up with. However, there a big gap between children’s rapidly growing physical and mental needs existing furniture. It necessary to design furniture both interesting multifunctional from perspective physiology psychology. In context artificial intelligence, this paper applies intelligence concept discusses necessity principles its application in aspects society, children, development trends.

The aim of this study was to assess the effect and mechanism through which berberine extract (BBR) protects colon mucosa mechanical barrier mice suffering from ulcerative colitis (UC).60 BALB/c were randomly divided into five groups, 12 per group: normal control group (group A), model B), BBR low-dose Creceived 50 mg/kg BBR), high-dose D -received 100 BBR) salazosulfapyridine (SASP) positive E 30 SASP).The UC reproduced using dextran sulphate sodium (DSS).After modelling, treated for 7...

In the big data environment, various systems and platforms have provided billions of points to researchers. The large amount user on social media has become a source for research many kinds research. However, few scholars realize ethical risks in collection utilization data, ignore needs users themselves. Users’ concerns should be considered when formulating guidelines. This study takes Sina Microblog (the world’s largest Chinese platform) as subject, hoping provide from evidence differences...

Artis-Zeego is an advanced interventional imaging system that can provide the three-dimensional (3-D) reconstruction of coronary artery in real time. However, mechanical accuracy will degenerate after long-time use. The inaccurate geometry affect spatial resolution 3-D reconstruction. We propose a calibration algorithm to tackle this problem. There are three steps our algorithm. First, we estimation based on classical helical phantom. Second, transfer nominal C-arm coordinate system. Third,...

To understand the knowledge of acupuncture disease spectrum, expectation treatment in Chengdu residents.A questionnaire regarding spectrum and residents was established. By field sampling internet survey, related data were collected analyzed.Totally 1 548 valid questionnaires collected, including 041 from survey 507 survey. The results indicated its moderate residents; among acupuncture, with highest cognition insomnia, accounting for 45.0% 75.4% survey; while lowest infertility, 8.3% 34.3%...

Objective To investigate the prevalence and related risk factors of anxiety symptoms in elderly patients from one community health service center Shanghai. Methods Patients aged 60 to 85 years visiting Kongjiang Community Health Service Center August December 2016 were included survey. The evaluated with Generalized Anxiety Disorder Scale-7 (GAD-7), Sociodemographic Health-related Variables Questionnaire, Mental Knowledge Scale Lubben Social Network...