A5081849902- Family Support in Illness
- Cancer survivorship and care
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Cancer Research and Treatments
- Childhood Cancer Survivors' Quality of Life
- Nanoplatforms for cancer theranostics
- Telomeres, Telomerase, and Senescence
- RNA modifications and cancer
- interferon and immune responses
- Helicobacter pylori-related gastroenterology studies
- Attachment and Relationship Dynamics
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Surgical Treatments
- Palliative Care and End-of-Life Issues
- Pediatric Pain Management Techniques
- Ferroptosis and cancer prognosis
- Cancer, Hypoxia, and Metabolism
- Art Therapy and Mental Health
- Colorectal and Anal Carcinomas
- Immune cells in cancer
- Patient-Provider Communication in Healthcare
- Urban Green Space and Health
- Enhanced Recovery After Surgery
- Neurofibromatosis and Schwannoma Cases
Ningxia Medical University
2020-2024
Jiangnan University
2020-2024
Nantong University
2024
Sun Yat-sen University
2024
Wuxi No.2 People's Hospital
2024
Second Affiliated Hospital of Jilin University
2021-2023
Dalian Medical University
2021
Second Affiliated Hospital of Dalian Medical University
2021
Central South University
2019
Nanjing Medical University
2019
Based on the relationship between gut microbiota and colorectal cancer, we developed a new probiotic powder for treatment of cancer. Initially, evaluated effect CRC using hematoxylin eosin staining, mouse survival rate tumor size. We then investigated effects microbiota, immune cells, apoptotic proteins 16S rDNA sequencing, flow cytometry, western blot, respectively. The results showed that improved intestinal barrier integrity, rate, reduced size in mice. This was associated with changes...
Abstract Although aspirin can reduce the incidence of colorectal cancer (CRC), there is still uncertainty about its significance as a treatment for CRC, and mechanism in CRC not well understood. In this study, we used to prevent AOM/DSS-induced mice, anti-CRC efficacy was assessed using haematoxylin eosin (H&E) staining by determining mouse survival rate tumour size. 16S rDNA sequencing, flow cytometry (FCM), Western blotting were also conducted investigate changes gut microbiota, immune...
To test the feasibility, acceptability and preliminary efficacy of using an integrated approach combined online in-person delivery to support colorectal cancer (CRC) patients their spousal caregivers coping positively with together.
To explore the dyadic interdependence of self-efficacy, benefit finding, anxiety, depression, and QOL in cancer patient (CP) family caregiver (FC) dyads, to ascertain effects self-efficacy on quality life (QOL) CP-FC dyads. Conducted from November 2014 December 2015, participants comprised 772 The study surveyed participant characteristics, QOL. Data were analyzed using Pearson's correlation, T-test, actor-partner mediation model (APIMeM). CPs' was positively correlated with both their own...
Under the guidance of a preliminary Live with Love Conceptual Framework, Caring for Couples Coping Colorectal Cancer (4Cs: CRC) programme was designed specifically colorectal cancer couples. The objectives this study included examining efficacy couples adapting to and comparing effects different intervention delivery modes (online, face-to-face blended) on couple outcomes.A four-arm randomized controlled trial conducted among Chinese were randomly assigned an online intervention, blended or...
Lung cancer is the most common malignant tumor in world, and its incidence mortality are very high. This study focuses on mechanism of non-small cell lung to find new therapeutic targets.We used RT-PCR Western blot verify linear relationship between E2F1 IRF5 normal tissue tissues. Secondly, we overexpression knock down lines detect expression IRF5. The prime enzyme reporter plasmid verified that binds core promoter region IRF5; finally, CHIP experiments demonstrated directly IRF5.We...
Tumor vaccines have achieved remarkable progress in treating patients with various tumors clinical studies. Nevertheless, extensive research has also revealed that tumor are not up to expectations for the treatment of solid due their low immunogenicity. Therefore, there is an urgent need design a vaccine can stimulate broad anti-tumor immune response.
This article aims to systematically present the completed process of developing and evaluating a web-based complex intervention called 'Caring for Couples Coping with Colorectal Cancer "4Cs: CRC" program'; summarize findings this integrated supportive program; provide valuable experience suggestions future interventions. The 4Cs: CRC program was guided by Medical Research Council (MRC) framework, which has widely been used develop evaluate Three stages were development, namely: (1)...
To explore the computed tomography (CT) features of gastric cancer (GC) patients with DNA mismatch repair deficiency (dMMR).This study reviewed clinical and CT GC dMMR, confirmed by postoperative results, between September 2017 December 2019. The expression pattern MMR major proteins (MLH1, MSH2, MSH6, PMS2) in immunohistochemistry was used to confirm status tissues. correlation pre-treatment statistically analyzed.A total 28 were diagnosed as dMMR our study, 49 MMR-proficient (pMMR). tumor...
Colorectal cancer (CRC) is a worldwide disease posing serious threats to people's life. Surgery and postsurgical chemotherapy are still the first choices control rapid progression of cancer. However, tumor recurrence even distant metastasis prone occur. As result, it in urgent demand find new method CRC while inhibiting metastasis. On this basis, study developed three-layered functionalized hydrogel-fibrous membrane-hydrogel composite materials. The Chinese traditional drugs 20...
Tai Chi Chuan (TCC) is a traditional Chinese mind-body exercise widely adopted in communities and colleges. However, the mindful essence of TCC rarely emphasized during popularization. This makes it difficult for beginners to benefit from it. The present study aimed examine effects Mindfulness-enhanced (MTCC) intervention, which enhances mindfulness components embedded within TCC, on mental physical health among beginners.
This study aims to understand the experiences of colorectal cancer (CRC) patients and their spousal caregivers during COVID-19 pandemic refine a self-efficacy (SE) intervention for these couples.
Aspirin is one of the most commonly prescribed medications. Evidence shows that it can even treat and prevent intestinal tumors. However, has also caused a great deal controversy due to its side effects. We therefore explored whether aspirin was beneficial or harmful intestines. used continuously interfered with C57BL/6 J mice for 48 weeks, examining their tissues at 13, 26 weeks determine drug's effect on In addition, we flow cytometry (FCM) detect T cells expression T-cell immunoreceptor...