Background: In recent years, the flipped classroom method of teaching has received much attention in health sciences education. However, application classrooms ophthalmology education not been well investigated.Objective: The goal this study was to investigate effectiveness and acceptability approach at clerkship level.Design: Ninety-five fourth year medical students an were randomly divided into two groups. An ocular trauma module chosen for content study. One group (FG (flipped group), n =...

Purpose To assess the demographics and distribution of corneal astigmatism before cataract surgery in Chinese patients. Setting State Key Laboratory Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. Design Clinic-based cross-sectional study. Methods From July 2009 to May 2011, preoperative bilateral partial coherence interferometry (IOLMaster) was performed consecutive patients having surgery. Patient keratometric data were recorded. Results The mean age...

To analyze the treatment modalities and trends for neovascular glaucoma (NVG) over past 10 years, we conducted a retrospective analysis at Zhongshan Ophthalmic Center on 1331 NVG inpatients who received 1459 treatments 1383 eyes between January 1, 2012, December 31, 2021. Over time, observed progressive annual increase in both number of patients volume surgeries NVG, with an percentage change (APC) 10.23% (95% confidence interval [CI]: 5.5-15.2%, P = 0.001) 11.59% CI: 6.6-16.9%, 0.001),...

Introduction: To investigate the effect of different levels early intraocular pressure (IOP) on long-term outcomes patients with primary open-angle glaucoma (POAG) who were treated trabeculectomy. Methods: This was a retrospective cohort study, total 74 (90 eyes) trabeculectomy surgery at single center from 2021 to 2022. Based IOP 1 day after surgery, they divided into high group (≥ 15mmHg) and low (< 15mmHg). The Student’s t-test chi-square test used compare differences between two...

Our purpose was to evaluate if temperature changes occur in maternal or fetal tissues during HASTE imaging.Pregnant pigs were scanned with the technique, and temperatures measured phase maps probes inserted into amniotic fluid brain.Fiberoptic showed that no heating occurred imaging.Our current protocols do not deposit a significant amount of heat gravid uterus. J. Magn. Reson. Imaging 2001;13:856-861.

To describe the severity and morphological features of high myopic maculopathy in Chinese patients to evaluate their association with age, refractive error visual acuity.Six hundred four eyes 337 (ages 8-88 years) myopia (refractive ≤ -6.0 D) presenting Zhongshan Ophthalmic Center were studied retrospectively. All underwent an ophthalmological examination including digital colour fundus photography. Fundus fluorescein angiography was performed 251 (443 eyes) indocyanine green 35 (63 eyes)....

To describe demographic features and clinical imaging characteristics of inflammatory choroidal neovascularization (CNV) in a Chinese population.A retrospective case review patients with CNV secondary to uveitis from 2002 2013.A total 125 (150 eyes, 166 CNVs; bifocal CNVs 16 eyes), 64% whom were women, reviewed. The mean age was 35.86 years. proportions punctate inner choroidopathy (PIC), multifocal choroiditis (MFC), Vogt-Koyanagi-Harada (VKH) 50.4, 22.4, 8%. All the cases classic...

In 29 gadolinium-enhanced breast magnetic resonance (MR) examinations, motion prevented accurate and efficient image processing. To compensate for global rotations translations, an automatic correction method with a ratio-variance minimization algorithm was used to align images at multiple time points through iterative process. This reduced improved the accuracy efficiency of lesion detection.

To characterize the clinical features of punctate inner choroidopathy (PIC) in Chinese patients.A retrospective chart review all patients admitted with PIC from June 1999 to October 2009.Of 75 (112 eyes) diagnosed PIC, 72% were women, 80% myopic, and 49% exhibited bilateral involvement. The mean age at presentation was 32 years. Blurred central vision (64%) scotoma (40%) most common symptoms. Multifocal lesions mostly restricted posterior pole (95%). acute yellow demonstrated...

To evaluate the efficacy and safety of intravitreal conbercept (KH902) as primary treatment choroidal neovascularization secondary to punctate inner choroidopathy. This study was a retrospective, consecutive, observational case series. We reviewed medical records 16 eyes (16 patients) with naive subfoveal or juxtafoveal punctuate choroidopathy that were treated injections. All patients completed at least six months follow-up. Best-corrected visual acuity (BCVA) measured, anatomical features...

Aim . To evaluate eye drop instillation technique and to explore its determinants in glaucoma patients. Methods One hundred thirteen patients diagnosed with self-administering topical antiglaucoma drops for at least 1 month were evaluated. All instilled artificial tear solution one as they would do home. The whole process was evaluated by two study staff. A comprehensive score system associated techniques used quantify the such demographic clinical characteristics. Results Half of (48.67%)...

This study aimed to identify key long noncoding RNAs (lncRNAs) in age-related macular degeneration (AMD) patients and relevant pathological mechanisms of AMD development. We identified 407 differentially expressed mRNAs 429 lncRNAs retinal pigment epithelium (RPE) retina the region versus controls (P < 0.05 |log2FC| > 0.585) from GSE135092. A total 14 were obtained through external data validation GSE115828. miRNA-mRNA miRNA-lncRNA network containing 52 lncRNA nodes, 49 miRNA mRNA nodes 351...

Purpose Trabeculectomy has been regarded as a mainstay of initial treatment in eyes angle closure glaucoma (ACG) with peripheral anterior synechia > 180° the Chinese population while its efficacy secondary ACG BEST1 gene mutation remains unclear. We set out to investigate outcome trabeculectomy for group patients autosomal recessive bestrophinopathy (ARB). Methods In this retrospective case series study, 8 ARB and their 4 recruited family members underwent thorough ophthalmic examination...

Purpose To determine the clinical characteristics and outcomes of patients with toxic retinopathy after phacoemulsification intraocular lens implantation when correct cefuroxime dilution is administered. Setting State Key Laboratory Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. Design Prospective case series. Methods Patients developing between January 2016 April 2017 were observed. All received an anterior chamber injection correctly diluted at end...

Noninvasive in vivo quantitation of boron is necessary for obtaining pharmacokinetic data on candidate boronated delivery agents developed neutron capture therapy (BNCT). Such data, turn, would facilitate the optimization temporal sequence drug infusion and irradiation. Current approaches to such include: positron emission tomography employing F‐18 labeled (e.g., p ‐boronophenylalanine), ex activation analysis blood (and very occasionally tissue) samples, nuclear magnetic resonance (NMR)...

NMR techniques for temperature and pH measurements have attracted increasing interest in recent years, motivated part by the growing importance of medical hyperthermia treatment cancer. The chemical shifts thulium 1, 4, 7, 10-tetraazacyclododecane-1, 10-tetrakis(methylene phosphonate) (TmDOTP5−) been studied as a function pH. results demonstrate that TmDOTP5− resonance are highly sensitive to (∼1.0 ppm/°C) (∼3.2 ppm/pH unit) at clinically relevant field strengths. A new method is presented...

Polypoidal choroidal vasculopathy (PCV) contains aneurismal morphologic and histopathologic feature it is considered to be a possible distinct entity from neovascular age-related macular degeneration (AMD). In this study, the association of identified risk variants for intracranial aneurysm on chromosome 9p21 with PCV AMD in Chinese Han population was investigated.The authors genotyped rs1333040 rs10757278 177 patients, 131 182 controls using genotyping method direct DNA sequencing. Allele...

The purpose of this study was to evaluate the intermediate surgical results Ahmed glaucoma valve (AGV) implantation in patients less than 7 years age, with advanced primary congenital who have failed previous surgeries.Consecutive that operations and had undergone subsequent AGV were evaluated retrospectively. Surgical success defined as 1) intraocular pressure (IOP) ≥6 ≤21 mmHg; 2) IOP reduction at least 30% relative preoperative values; 3) without need for additional intervention control,...