- Advanced biosensing and bioanalysis techniques
- Graphene research and applications
- Advanced Sensor and Energy Harvesting Materials
- Neuroscience and Neural Engineering
- Molecular Sensors and Ion Detection
- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- Photoreceptor and optogenetics research
- Luminescence and Fluorescent Materials
- Graphene and Nanomaterials Applications
- Biosensors and Analytical Detection
- Advanced Wireless Communication Technologies
- Quantum Dots Synthesis And Properties
- Organic Light-Emitting Diodes Research
- SARS-CoV-2 detection and testing
- CRISPR and Genetic Engineering
- Molecular Junctions and Nanostructures
- Organic Electronics and Photovoltaics
- Alzheimer's disease research and treatments
- Advanced MIMO Systems Optimization
- Advanced Materials and Mechanics
- Microfluidic and Capillary Electrophoresis Applications
- Supramolecular Self-Assembly in Materials
- Advanced Memory and Neural Computing
- Chalcogenide Semiconductor Thin Films
City University of Hong Kong
2015-2024
Tongji University
2024
University of Connecticut
2021-2023
Chongqing University of Posts and Telecommunications
2021-2023
University of Missouri
2019-2020
Shantou University
2013-2019
University of Shanghai for Science and Technology
2018
Significance Neuroscience studies using optogenetics have greatly improved our understanding of brain circuits. Advances in the combined use and pharmacology to further probe important neurochemical signals has lagged, however, large part due inconvenience conventional cannulated approaches, as well difficulty controlling, powering, manufacturing optofluidic devices that are reliable scalable for distribution neuroscience community. Here, we present a battery-free, wireless, lightweight...
HgSe CQD based narrowband photodetectors with plasmonic nano-disk arrays were developed for the detection of mid-wave infrared.
Abstract This study reports biosensing using graphene field‐effect transistors with the aid of pyrene‐tagged DNA aptamers, which exhibit excellent selectivity, affinity, and stability for Escherichia coli ( E. ) detection. The aptamer is employed as sensing probe due to its advantages such high affinity toward small molecules even whole cells. change carrier density in probe‐modified attachment discussed theoretically first time also verified experimentally. conformational binding brings...
Electrolytes play a pivotal role in regulating cardiovascular functions, hydration, and muscle activation. The current standards for monitoring electrolytes involve periodic sampling of blood measurements using laboratory techniques, which are often uncomfortable/inconvenient to the subjects add considerable expense management their underlying disease conditions. wide range skin interstitial fluids (ISFs) correlations with those plasma create exciting opportunities applications such as...
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems have recently received notable attention for their applications in nucleic acid detection. Despite many attempts, the majority of current CRISPR-based biosensors infectious respiratory disease diagnostic still require target preamplifications. This study reports a new biosensor amplification-free detection via harnessing trans-cleavage mechanism Cas13a and ultrasensitive graphene...
The real-time monitoring of neurochemical release in vivo plays a critical role understanding the biochemical process complex nervous system. Current technologies for such applications, including microdialysis and fast-scan cyclic voltammetry, suffer from limited spatiotemporal resolution or poor selectivity. Here, we report soft implantable aptamer-graphene microtransistor probe release. As demonstration, show dopamine with nearly cellular-scale spatial resolution, high selectivity...
Quantitative polymerase chain reaction as a powerful tool for DNA detection has been pivotal to vast range of applications, including disease screening, food safety assessment, environmental monitoring, and many others. However, the essential target amplification step in combination with fluorescence readout poses significant challenge rapid streamlined analysis. The discovery engineering clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR-associated (Cas) technology...
Synergy between optical and electrical properties, namely, deep-blue emission (color saturation: (0.15,0.10)) a high carrier mobility (stemming from π–π stacking) are demonstrated in novel planar linear molecular design for effective electroluminescence with yield of 5.48 cd A−1. As service to our authors readers, this journal provides supporting information supplied by the authors. Such materials peer reviewed may be re-organized online delivery, but not copy-edited or typeset. Technical...
Neurochemical corelease has received much attention in understanding brain activity and cognition. Despite many attempts, the multiplexed monitoring of coreleased neurochemicals with spatiotemporal precision minimal crosstalk using existing methods remains challenging. Here, we report a soft neural probe for neurochemical via electrografting-assisted site-selective functionalization aptamers on graphene field-effect transistors (G-FETs). The probes possess excellent flexibility, ultralight...
Accurate spatial-temporal traffic modeling and prediction play an important role in intelligent transportation systems (ITS). Recently, various deep learning methods such as graph convolutional networks (GCNs) recurrent neural (RNNs) have been widely adopted tasks to extract dependencies based on a large volume of high-quality training data. However, there exist data scarcity problems some networks, these cases, the performance traditional GCNs RNNs approaches will degrade sharply. To...
Energy-efficient, miniaturized electronic ocean sensors for monitoring and recording various environmental parameters remain a challenge because conventional require high-pressure chambers seals to survive the large hydrostatic pressure harsh environment, which usually entail high-power supply size of sensor system. Herein, we introduce soft, pressure-tolerant, flexible that can operate under salinity environments, thereby eliminating need reducing power consumption size. Using resistive...
In this study, a novel violet-blue emitter <bold>m-BBTPI</bold> was designed and synthesized <italic>via meta</italic>-molecular tailoring. Using as non-doped emitter, we obtained high-efficiency organic electroluminescent device.
Silicone elastomers, such as poly(dimethylsiloxane) (PDMS), have a broad range of applications in basic biomedical research and clinical medicine, ranging from the preparation microfluidic devices for organs-on-chips ventriculoperitoneal shunts treatment hydrocephalus to implantable neural probes neuropharmacology. Despite importance, protein adsorptions on silicone elastomers these application environments represent significant challenge. Surface coatings with slippery lubricants, inspired...
The existence of bacteria is a great threat to food safety. Volatile compounds secreted by during their metabolic process can be dissected evaluate bacterial contamination. Indole, as major volatile molecule released Escherichia coli (E. coli), was chosen examine the presence E. in this research. In work, graphene field-effect transistor (G-FET) employed detect molecule-indole based on π-π stacking interaction between indole and graphene. exposure G-FET devices provokes change electrical...
Foodborne illness is correlated with the existence of infectious pathogens such as bacteria in food and drinking water. Probe-modified graphene field effect transistors (G-FETs) have been shown to be suitable for Escherichia coli (E. coli) detection. Here, G-FETs bacterial detection are modeled simulated COMSOL Multiphysics understand operation biosensors. The motion E. cells electrolyte surface charge induced by systematically investigated. comparison between simulation experimental data...
This study developed an in-field analytical technique for food samples by integrating filtration into a surface-enhanced Raman spectroscopy (SERS) microchip. microchip embedded filter membrane in the chip inlet to eliminate interfering particulates and enrich target analytes. The design geometry of channel were optimised finite-elemental method (FEM) tailor variations flow velocity (within 0–24 μL/s) facilitate efficient mixing filtrate with nanoparticles two steps. Four pesticides...
Extensive studies in both animals and humans have demonstrated that high molecular weight neurochemicals, such as neuropeptides other polypeptide play critical roles various neurological disorders. Despite many attempts, existing methods are constrained by detecting neuropeptide release small animal models during behavior tasks, which leaves the mechanisms underlying psychological disorders unresolved. Here, we report a wireless, programmable push-pull microsystem for membrane-free...
Microfluidic devices are gaining extensive interest due to their potential applications in wide-ranging areas, including lab-on-a-chip devices, fluid delivery, and artificial vascular networks. Most current microfluidic a planar design with fixed configurations once formed, which limits such as engineered networks biology programmable drug delivery systems. Here, shape-programmable three-dimensional (3D) structures, assembled from bilayer of channel-embedded polydimethylsiloxane (PDMS)...