Guangfu Wu

ORCID: 0000-0002-4714-4568
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About
Contact & Profiles
Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Graphene research and applications
  • Advanced Sensor and Energy Harvesting Materials
  • Neuroscience and Neural Engineering
  • Molecular Sensors and Ion Detection
  • Analytical Chemistry and Sensors
  • Electrochemical sensors and biosensors
  • Photoreceptor and optogenetics research
  • Luminescence and Fluorescent Materials
  • Graphene and Nanomaterials Applications
  • Biosensors and Analytical Detection
  • Advanced Wireless Communication Technologies
  • Quantum Dots Synthesis And Properties
  • Organic Light-Emitting Diodes Research
  • SARS-CoV-2 detection and testing
  • CRISPR and Genetic Engineering
  • Molecular Junctions and Nanostructures
  • Organic Electronics and Photovoltaics
  • Alzheimer's disease research and treatments
  • Advanced MIMO Systems Optimization
  • Advanced Materials and Mechanics
  • Microfluidic and Capillary Electrophoresis Applications
  • Supramolecular Self-Assembly in Materials
  • Advanced Memory and Neural Computing
  • Chalcogenide Semiconductor Thin Films

City University of Hong Kong
2015-2024

Tongji University
2024

University of Connecticut
2021-2023

Chongqing University of Posts and Telecommunications
2021-2023

University of Missouri
2019-2020

Shantou University
2013-2019

University of Shanghai for Science and Technology
2018

Significance Neuroscience studies using optogenetics have greatly improved our understanding of brain circuits. Advances in the combined use and pharmacology to further probe important neurochemical signals has lagged, however, large part due inconvenience conventional cannulated approaches, as well difficulty controlling, powering, manufacturing optofluidic devices that are reliable scalable for distribution neuroscience community. Here, we present a battery-free, wireless, lightweight...

10.1073/pnas.1909850116 article EN Proceedings of the National Academy of Sciences 2019-10-10

HgSe CQD based narrowband photodetectors with plasmonic nano-disk arrays were developed for the detection of mid-wave infrared.

10.1039/c6tc04248a article EN Journal of Materials Chemistry C 2016-11-30

Abstract This study reports biosensing using graphene field‐effect transistors with the aid of pyrene‐tagged DNA aptamers, which exhibit excellent selectivity, affinity, and stability for Escherichia coli ( E. ) detection. The aptamer is employed as sensing probe due to its advantages such high affinity toward small molecules even whole cells. change carrier density in probe‐modified attachment discussed theoretically first time also verified experimentally. conformational binding brings...

10.1002/adhm.201700736 article EN Advanced Healthcare Materials 2017-08-10

Electrolytes play a pivotal role in regulating cardiovascular functions, hydration, and muscle activation. The current standards for monitoring electrolytes involve periodic sampling of blood measurements using laboratory techniques, which are often uncomfortable/inconvenient to the subjects add considerable expense management their underlying disease conditions. wide range skin interstitial fluids (ISFs) correlations with those plasma create exciting opportunities applications such as...

10.1021/acssensors.0c02330 article EN ACS Sensors 2021-05-26

The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems have recently received notable attention for their applications in nucleic acid detection. Despite many attempts, the majority of current CRISPR-based biosensors infectious respiratory disease diagnostic still require target preamplifications. This study reports a new biosensor amplification-free detection via harnessing trans-cleavage mechanism Cas13a and ultrasensitive graphene...

10.1002/anie.202203826 article EN Angewandte Chemie International Edition 2022-05-12

The real-time monitoring of neurochemical release in vivo plays a critical role understanding the biochemical process complex nervous system. Current technologies for such applications, including microdialysis and fast-scan cyclic voltammetry, suffer from limited spatiotemporal resolution or poor selectivity. Here, we report soft implantable aptamer-graphene microtransistor probe release. As demonstration, show dopamine with nearly cellular-scale spatial resolution, high selectivity...

10.1021/acs.nanolett.2c00289 article EN Nano Letters 2022-04-19

Quantitative polymerase chain reaction as a powerful tool for DNA detection has been pivotal to vast range of applications, including disease screening, food safety assessment, environmental monitoring, and many others. However, the essential target amplification step in combination with fluorescence readout poses significant challenge rapid streamlined analysis. The discovery engineering clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR-associated (Cas) technology...

10.1021/acssensors.2c02495 article EN ACS Sensors 2023-04-07

Synergy between optical and electrical properties, namely, deep-blue emission (color saturation: (0.15,0.10)) a high carrier mobility (stemming from π–π stacking) are demonstrated in novel planar linear molecular design for effective electroluminescence with yield of 5.48 cd A−1. As service to our authors readers, this journal provides supporting information supplied by the authors. Such materials peer reviewed may be re-organized online delivery, but not copy-edited or typeset. Technical...

10.1002/adom.201400078 article EN Advanced Optical Materials 2014-03-20

Neurochemical corelease has received much attention in understanding brain activity and cognition. Despite many attempts, the multiplexed monitoring of coreleased neurochemicals with spatiotemporal precision minimal crosstalk using existing methods remains challenging. Here, we report a soft neural probe for neurochemical via electrografting-assisted site-selective functionalization aptamers on graphene field-effect transistors (G-FETs). The probes possess excellent flexibility, ultralight...

10.1021/acs.analchem.1c05531 article EN Analytical Chemistry 2022-06-09

Accurate spatial-temporal traffic modeling and prediction play an important role in intelligent transportation systems (ITS). Recently, various deep learning methods such as graph convolutional networks (GCNs) recurrent neural (RNNs) have been widely adopted tasks to extract dependencies based on a large volume of high-quality training data. However, there exist data scarcity problems some networks, these cases, the performance traditional GCNs RNNs approaches will degrade sharply. To...

10.1109/tits.2023.3250424 article EN IEEE Transactions on Intelligent Transportation Systems 2023-03-07

Energy-efficient, miniaturized electronic ocean sensors for monitoring and recording various environmental parameters remain a challenge because conventional require high-pressure chambers seals to survive the large hydrostatic pressure harsh environment, which usually entail high-power supply size of sensor system. Herein, we introduce soft, pressure-tolerant, flexible that can operate under salinity environments, thereby eliminating need reducing power consumption size. Using resistive...

10.1021/acssensors.2c01059 article EN ACS Sensors 2022-08-11

In this study, a novel violet-blue emitter <bold>m-BBTPI</bold> was designed and synthesized <italic>via meta</italic>-molecular tailoring. Using as non-doped emitter, we obtained high-efficiency organic electroluminescent device.

10.1039/c4ra16954a article EN RSC Advances 2015-01-01

Silicone elastomers, such as poly(dimethylsiloxane) (PDMS), have a broad range of applications in basic biomedical research and clinical medicine, ranging from the preparation microfluidic devices for organs-on-chips ventriculoperitoneal shunts treatment hydrocephalus to implantable neural probes neuropharmacology. Despite importance, protein adsorptions on silicone elastomers these application environments represent significant challenge. Surface coatings with slippery lubricants, inspired...

10.1021/acsami.2c20834 article EN ACS Applied Materials & Interfaces 2023-02-10

The existence of bacteria is a great threat to food safety. Volatile compounds secreted by during their metabolic process can be dissected evaluate bacterial contamination. Indole, as major volatile molecule released Escherichia coli (E. coli), was chosen examine the presence E. in this research. In work, graphene field-effect transistor (G-FET) employed detect molecule-indole based on π-π stacking interaction between indole and graphene. exposure G-FET devices provokes change electrical...

10.3390/nano11051155 article EN cc-by Nanomaterials 2021-04-28

Foodborne illness is correlated with the existence of infectious pathogens such as bacteria in food and drinking water. Probe-modified graphene field effect transistors (G-FETs) have been shown to be suitable for Escherichia coli (E. coli) detection. Here, G-FETs bacterial detection are modeled simulated COMSOL Multiphysics understand operation biosensors. The motion E. cells electrolyte surface charge induced by systematically investigated. comparison between simulation experimental data...

10.3390/s18061715 article EN cc-by Sensors 2018-05-25

10.1016/j.saa.2019.117506 article EN Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 2019-09-02

This study developed an in-field analytical technique for food samples by integrating filtration into a surface-enhanced Raman spectroscopy (SERS) microchip. microchip embedded filter membrane in the chip inlet to eliminate interfering particulates and enrich target analytes. The design geometry of channel were optimised finite-elemental method (FEM) tailor variations flow velocity (within 0–24 μL/s) facilitate efficient mixing filtrate with nanoparticles two steps. Four pesticides...

10.1080/19440049.2021.1881624 article EN Food Additives & Contaminants Part A 2021-03-10

Extensive studies in both animals and humans have demonstrated that high molecular weight neurochemicals, such as neuropeptides other polypeptide play critical roles various neurological disorders. Despite many attempts, existing methods are constrained by detecting neuropeptide release small animal models during behavior tasks, which leaves the mechanisms underlying psychological disorders unresolved. Here, we report a wireless, programmable push-pull microsystem for membrane-free...

10.1126/sciadv.abn2277 article EN cc-by-nc Science Advances 2022-02-23

Microfluidic devices are gaining extensive interest due to their potential applications in wide-ranging areas, including lab-on-a-chip devices, fluid delivery, and artificial vascular networks. Most current microfluidic a planar design with fixed configurations once formed, which limits such as engineered networks biology programmable drug delivery systems. Here, shape-programmable three-dimensional (3D) structures, assembled from bilayer of channel-embedded polydimethylsiloxane (PDMS)...

10.1021/acsami.1c24799 article EN ACS Applied Materials & Interfaces 2022-03-23
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