- Health Systems, Economic Evaluations, Quality of Life
- Prostate Cancer Diagnosis and Treatment
- Healthcare Policy and Management
- Cancer survivorship and care
- Economic and Financial Impacts of Cancer
- Global Cancer Incidence and Screening
- Patient-Provider Communication in Healthcare
- Patient Satisfaction in Healthcare
- Lung Cancer Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- Prostate Cancer Treatment and Research
- Palliative Care and End-of-Life Issues
- Photodynamic Therapy Research Studies
- HIV, Drug Use, Sexual Risk
- Opioid Use Disorder Treatment
- Global Health Care Issues
- Healthcare Systems and Reforms
- Suicide and Self-Harm Studies
- Multiple and Secondary Primary Cancers
- Migration, Health and Trauma
- Bladder and Urothelial Cancer Treatments
- Adolescent Sexual and Reproductive Health
- Urinary Bladder and Prostate Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Substance Abuse Treatment and Outcomes
University of Pennsylvania
2016-2025
Philadelphia VA Medical Center
2020-2025
United States Department of Veterans Affairs
2021-2025
VA Pittsburgh Healthcare System
2021
Veterans Health Administration
2021
Johns Hopkins University
2019
Philadelphia University
2010-2019
National Institute on Aging
2015
National Institutes of Health
2015
Treatment Research Institute
2014
Abstract Objective We sought to analyze the prevalence and incremental burden of depression among elderly with prostate cancer. Methods adopted a retrospective cohort design using Surveillance, Epidemiology End Results‐Medicare linked database between 1995 2003. Patients cancer diagnosed 1998 were identified followed retrospectively for 1 year pre‐diagnosis up 8 years post diagnosis. In this patients cancer, during treatment phase (1 after diagnosis cancer) or in follow‐up was International...
Substance abuse is a growing, but mostly silent, epidemic among older adults. We sought to analyze the trends in admissions for substance treatment adults (aged 55 and older). Treatment Episode Data Set - Admissions (TEDS-A) period between 2000 2012 was used. The admission primary substances, demographic attributes, characteristics of abused type were analyzed. While total number changed slightly, proportion attributable increased from 3.4% 7.0%. Substantial changes demographic, use pattern,...
<h3>Importance</h3> The association between androgen deprivation therapy (ADT) exposure and dementia is uncertain. <h3>Objective</h3> To analyze the ADT diagnosis of Alzheimer disease or among elderly men with prostate cancer. <h3>Design, Setting, Participants</h3> This retrospective cohort study used data from National Cancer Institute’s Surveillance, Epidemiology, End Results–Medicare linked database. Participants were 154 089 newly diagnosed cancer 1996 2003. analyses conducted November...
Importance Guidelines recommend shared decision-making prior to initiating lung cancer screening (LCS). However, evidence is lacking on how best implement in clinical practice. Objective To evaluate the impact of an LCS Decision Tool (LCSDecTool) quality and uptake. Design, Setting, Participants This randomized trial enrolled participants at Veteran Affairs Medical Centers Philadelphia, Pennsylvania; Milwaukee, Wisconsin; West Haven, Connecticut, from March 18, 2019, September 29, 2021, with...
Objectives: Compare HIV injecting and sex risk in patients being treated with methadone (MET) or buprenorphine–naloxone (BUP). Methods: Secondary analysis from a study of liver enzyme changes randomized to MET BUP who completed 24 weeks treatment had 4 more blood draws. The initial 1:1 randomization was changed 2:1 (BUP:MET) after 18 months due higher dropout BUP. Risk Behavior Survey measured before 30 days at baseline 12 24. Results: Among 529 MET, 391 (74%) were completers; among 740 BUP,...
Stress is implicated in the pathogenesis and progression of HIV. The Transcendental Meditation (TM) a behavioral stress reduction program that incorporates mind-body approach, has demonstrated effectiveness improving outcomes via reduction. We evaluated feasibility implementing TM its effects on persons with In this community-based single blinded Phase-I, randomized controlled trial, (psychological physiological stress, immune activation, generic HIV-specific health-related quality life,...
Recruitment and retention strategies for patient-centered outcomes research are evolving on the subject is limited. In this work, we present a conceptual model of recruitment retention, describe activities related challenges in comparative effectiveness trial. This multicenter, longitudinal randomized controlled trial localized prostate cancer patients. We recruited 743 participants from three sites over 15 months period (January 2014 to March 2015), followed them 24 months. At site 1, 773...
Objective To determine the minimal important difference ( MID ) in generic and prostate‐specific health‐related quality of life HRQoL using distribution‐ anchor‐based methods. Study Design Setting Prospective cohort study 602 newly diagnosed prostate cancer patients recruited from an urban academic hospital a V eterans A dministration hospital. Participants completed SF ‐36) surveys at baseline 3, 6, 12, 24 months posttreatment. Anchor‐based distribution‐based methods were used to develop...
PURPOSE To study the effectiveness of Patient Preferences for Prostate Cancer Care (PreProCare) intervention in improving primary outcome satisfaction with care and secondary outcomes decision, decision regret, treatment choice among patients localized prostate cancer. METHODS In this multicenter randomized controlled study, we randomly assigned cancer to PreProCare or usual care. Outcomes were care, choice. Assessments performed at baseline 3, 6, 12, 24 months, analyzed using repeated...
Improving gender-sensitive suicide prevention programming for women veterans is crucial. Veterans Crisis Line (VCL) a preventive strategy used by the US Department of Affairs. Public health measures implemented during COVID-19 pandemic may have affected nature VCL calls.
Abstract Background Maintaining functional status, defined as the ability to perform daily activities such bathing, dressing, and preparing meals, is central older adults’ quality of life, health, remain independent. Identifying impairments – having difficulty or needing help performing these essential for clinicians provide optimal care adults, on a population level, understanding function can anticipate service needs. Yet uptake standardized measurement status into routine patient has been...
Out-of-pocket and indirect (OPI) costs play an important role in prostate cancer (PCa) outcomes research. We sought to analyze OPI of newly diagnosed PCa patients receiving either radical prostatectomy (RP) or external beam radiation therapy (EBRT).Prospective cohort design was used recruit 512 from urology clinics urban academic hospital a Veterans Administration medical center. Participants provided demographic information completed self-reported generic prostate-specific Health Related...
Data regarding the association between photodynamic therapy (PDT) and mortality in lung cancer patients are limited. We analyzed PDT with stage III or IV non-small cell (NSCLC) using data from National Cancer Database (NCDB) 2004 2016. From NCDB, we identified receiving laser ablation/cryosurgery local tumor destruction/excision (which includes PDT). Medicare Medicaid claims 2000 2013, NSCLC those bronchoscopy, then used these to confirm treatment. extracted who received radiation...
Background: While psychological difficulties, such as depression, among prostate cancer patients are known, their longitudinal burden remains understudied. We assessed the of depression across low-, intermediate- and high-risk groups, association between regret long-term depression. Methods: Secondary analysis data from a multi-centered randomized controlled study localized was carried out. Assessments were performed at baseline, 3-, 6-, 12- 24-month follow-up. Depression using Center for...
There is sparse evidence on community practice patterns in treating women with breast cancer. This study compared care of cancer from meta-analyses and US National Comprehensive Cancer Network (NCCN) clinical guidelines. Records 4395 were abstracted practices 19 surgeon oncologists six specialty the Philadelphia region during 1995–1999. Patients followed through December 2001. Low-frequency data obtained all patients. All other a random sample 464 women, minimum 50 patients per practice....
Ethnic variation in patient-reported outcomes such as health-related quality of life (HRQoL) and satisfaction with care are understudied areas the management elderly prostate cancer (PCa) patients.In this prospective cohort study, between years 2002 2004, authors recruited 214 older (>or=65 years) men newly diagnosed PCa from an urban academic hospital a Veterans Administration hospital. Participants completed generic (SF-36), prostate-specific (UCLA-PCI) HRQoL, (CSQ-8) surveys at baseline...
Background. Patients’ assessment of satisfaction with care, quality and outcomes has become a central issue in patient-centered prostate cancer (PCa) care. We sought to analyze the association between patient-reported care health-related life (HRQoL) newly diagnosed PCa patients. Methods. Prospective cohort design was used recruit 590 patients from an urban academic hospital VA hospital. Participants completed (CSQ-8) HRQoL (SF-36 UCLA-PCI) surveys prior treatment at 3, 6, 12, 24 months’...
BACKGROUND Substance use disorder in patients with cancer has implications for outcomes. The objective of this study was to analyze the effects type and timing substance on outcomes elderly Medicare recipients advanced prostate cancer. METHODS This an observational cohort using Surveillance, Epidemiology, End Results (SEER)‐Medicare linked data from 2000 2009. Among men who were diagnosed between 2001 2004, we identified those had a claim year before diagnosis, 1 after additional 4 years...
Abstract BACKGROUND: The objective of this study was to assess the racial and ethnic disparities in outcomes their association with process‐of‐care measures for elderly Medicare recipients localized prostate cancer. METHODS: Surveillance, Epidemiology, End Results‐Medicare databases period from 1995 2003 were used identify African‐American men, non‐Hispanic white Hispanic men cancer, data obtained 1‐year before diagnosis cancer up 8 years postdiagnosis. short‐term interest complications,...
Aims To analyze the risk of falls associated with Overactive bladder (OAB), and effects OAB treatment on among older adult Medicare fee‐for‐service enrollees. Methods Population based retrospective longitudinal cohort design study using 5% claims between 2006 2010. Patients a diagnosis (ICD 9: 596.51); Urinary Incontinence 788.3); incontinence, unspecified 788.30); Urge incontinence 788.31); Mixed (male, female) 788.33); frequency 788.41); Nocturia 788.43); or Urgency urination 788.63) were...