A5006457971- Research in Cotton Cultivation
- Suicide and Self-Harm Studies
- Mental Health Treatment and Access
- Plant Stress Responses and Tolerance
- Sleep and related disorders
- Photosynthetic Processes and Mechanisms
- Mental Health Research Topics
- Plant Gene Expression Analysis
- Sinusitis and nasal conditions
- Plant Molecular Biology Research
- Cardiac Health and Mental Health
- Plant biochemistry and biosynthesis
- Nasal Surgery and Airway Studies
- Higher Education and Teaching Methods
- Treatment of Major Depression
- Health disparities and outcomes
- Tracheal and airway disorders
- Plant nutrient uptake and metabolism
- Psychosomatic Disorders and Their Treatments
- COVID-19 and Mental Health
- Posttraumatic Stress Disorder Research
- Allergic Rhinitis and Sensitization
- Plant Reproductive Biology
- Youth Substance Use and School Attendance
- Workplace Health and Well-being
West Virginia University
2016-2025
Chinese Academy of Agricultural Sciences
2018-2023
Zhengzhou University
2021-2023
VA Pittsburgh Healthcare System
2021-2023
Anyang Institute of Technology
2010-2023
VA Healthcare-VISN 4
2021-2023
University of Pittsburgh
2021-2023
University of California, San Diego
2013-2022
Cotton Research Institute
2018-2022
Mental Illness Research, Education and Clinical Centers
2021-2022
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify intermediates or repair resulting damage. Glutaredoxins (GRXs) are ubiquitous oxidoreductase enzymes involved in diverse cellular processes play key role oxidative responsive mechanisms. This study was aimed explore structure–function relationship provide framework for functional validation biochemical characterization various GRX...
Abstract Background Cotton is an important industrial crop and a pioneer for saline-alkali land restoration. However, the molecular mechanism underlying cotton response to salt not completely understood. Methods Here, we used metabolome data transcriptome analyze tolerance regulatory network of metabolic biomarkers. Results In this study, was stressed at 400 m M NaCl 0 h, 3 24 h 48 h. interfered with gene expression, altered metabolite contents affected plant growth. Metabolome analysis...
Objective: Research suggests sleep disturbance plays a role in depression and risk for suicidal behavior (i.e., ideation, attempts, death by suicide). How affects suicide is unclear one's ability to perform activities of daily living (ADLs) may help explain this relation. This study examined associations between problems, ADLs, either depressive symptoms or among older adults. We hypothesized that ADLs would mediate relations problems risk.Method: Participants (N = 134; age ≥65) were...
High concentrations of heavy metals in the soil should be removed for environmental safety. Cadmium (Cd) is a metal that pollutes when its concentration exceeds 3.4 mg/kg. Although potential use cotton to remediate Cd-polluted soils known, little understood about molecular mechanisms Cd tolerance. In this study, transcriptome analysis was used identify tolerance genes and their cotton. We exposed plants excess identified 4627 differentially expressed (DEGs) root, 3022 DEGs stem 3854 leaves...
Alkaline stress is one of the abiotic stresses limiting cotton production. Though RNA-Seq analyses, have been conducted to investigate genome-wide gene expression in response alkaline plants, sodium bicarbonate (NaHCO3) stress-related genes has not reported. To explore mechanisms this stress, we used next-generation sequencing (NGS) technology study transcriptional changes under NaHCO3 stress. A total 18,230 and 11,177 differentially expressed (DEGs) were identified roots leaves,...
Abstract Verticillium dahliae is a soil‐borne, phytopathogenic fungus that causes wilt in cotton. Salt tolerance of cotton plants suffering from was significantly improved, but the mechanism unknown. In this study, we built symbiont named Cotton≡VD by immersing plant roots into liquid for four days. This resulted strong interaction between hyphae and roots. Under NaCl treatment 24 h, displayed less leaf wilting improved root growth compared with control. Biochemical tests SOD, POD CAT showed...
Objectives: Drug-induced sleep endoscopy (DISE) is increasingly being used in children with obstructive apnea (OSA) to identify specific sites of upper airway obstruction and plan surgical interventions. This study aims test the reliability validity a new grading system for pediatric DISE procedures (PedDISE-8). Methods: We conducted retrospective chart review 0 18 years old OSA who underwent DISE. Four independent raters reviewed graded each video recording twice using PedDISE-8. Eight were...
Introduction Neck mass is the most common presentation of human papillomavirus-related (HPV-related) oropharyngeal squamous cell carcinoma (OPSCC). Recently, circulating tumor HPV-DNA (ctHPVDNA) assays have been developed to detect active OPSCC. This pilot study investigates diagnostic accuracy ctHPVDNA in establishing HPV status for known vs. unknown OPSCC presenting as a neck mass. Methods A single-institution was conducted on all patients with between 2021 and 2022. The compared that...
Insomnia disorders affect up to 10% of adults and are associated with other health problems poor quality life. Cognitive Behavioral Therapy for (CBT-I) is an effective treatment; however, its effectiveness hindered by attendance adherence treatment recommendations. The present study sought identify predictors in CBT-I. Participants were 108 insomnia disorder. primarily female (71.3%), middle aged (mean age = 50.5), Caucasian (92.6%). Demographic variables, physical problems, Beck Anxiety...
Pet ownership literature remains mixed regarding associations with mental and physical health outcomes among older adults. The present study investigates the relationship between pet depression, health, activity in an adult sample balanced by sex (male/female), race (White/Black), urban/rural status. Participants were adults aged 65+ recruited 1999 2001 University of Alabama at Birmingham Study Aging. completed Geriatric Depression Scale, a single-item self-reported measure, questionnaire....
Flooding is among the most severe abiotic stresses in plant growth and development. The mechanism of submergence tolerance cotton response to stress unknown.The transcriptome results showed that a total 6,893 differentially expressed genes (DEGs) were discovered under stress. Gene Ontology (GO) enrichment analysis DEGs involved various or stimulus responses. Kyoto Encyclopedia Genes Genomes (KEGG) pathway indicated related hormone signal transduction, starch sucrose metabolism, glycolysis...
Cysteine, an early sulfur-containing compound in plants, is of significant importance sulfur metabolism. CYS encodes cysteine synthetase that further catalyzes synthesis. In this investigation, genes, identified from genome-wide analysis Gossypium hirsutum bioinformatically, led to the discovery GhCYS2 as pivotal gene responsible for Cd2+ response. The silencing through virus-induced (VIGS) rendered plants highly susceptible stress. Silencing resulted diminished levels and glutathione while...
Although efforts have been taken to exploit diversity for yield and quality improvements, limited progress on using beneficial alleles in domesticated undomesticated cotton varieties is limited. Given the complexity amount of genomic information since completion four genomes, characterizing significant variations haplotype block inheritance under artificial selection has challenging. Here we sequenced Gossypium hirsutum L. cv CRI-12 (the variety with largest acreage China), its parental...
Objective: Dementia-related anxiety is associated with general and depression, which are risk factors for suicidal ideation. Consequently, dementia-related may be When faced a negative event (e.g. developing dementia), individuals primarily employ monitoring or blunting styles of coping. The present study investigated whether coping were ideation in adults moderated the relation between ideation.Methods: Online Mturk participants (n = 330) completed Miller Behavioral Style Scale, Dementia...
Abstract Background Flavonols play important roles in antioxidation and anticancer activities, longevity, cardiovascular protection. Flavonol synthase ( FLS ) is a key enzyme for flavonol synthesis. Result Phenotypic, transcriptional metabolic data were analyzed, which showed that there was close relationship between salt stress flavonoids, flavonols significantly upregulated under stress. Nine, seven, four, four genes identified Gossypium hirsutum , barbadense arboreum raimondii,...
Abstract Cytokinin oxidase/dehydrogenase (CKX) is a key regulatory enzyme for the irreversible degradation of plant hormone cytokinin (CK), which important in growth and development response to abiotic stresses cotton. In this study, 27, 28, 14 CKXs were screened by FAD structural domain binding Gossypium hirsutum , barbadense arboreum raimondii respectively. Their phylogenetic relationships expression patterns analyzed, most GhCKXs found be tissue-specific responsive various such as cold,...
Depression symptoms are key risk factors for suicide; however, older adults differ from younger in types of depression experienced and thus their suicide. The present brief report investigated relations between different suicide whether these moderated by age. Participants were 944 community-dwelling (N = 512, M 39) 432, 66) the United States recruited through Mechanical Turk. completed self-report measures on risk. Age was found to moderate relation cognitive-affective somatic Younger age...
Fewer than half of patients with major depressive disorder (MDD) respond to psychotherapy. Pre-emptively informing their likelihood responding could be useful as part a patient-centered treatment decision-support plan.This prospective observational study examined national sample 807 beginning psychotherapy for MDD at the Veterans Health Administration. Patients completed self-report survey baseline and 3-months follow-up (data collected 2018-2020). We developed machine learning (ML) model...