A5084480990- Microbial Metabolic Engineering and Bioproduction
- Plant Pathogens and Fungal Diseases
- Plant-Microbe Interactions and Immunity
- Bacterial Genetics and Biotechnology
- Microbial Natural Products and Biosynthesis
- Enzyme Structure and Function
- Genomics and Phylogenetic Studies
- Legume Nitrogen Fixing Symbiosis
- RNA and protein synthesis mechanisms
- Metabolism, Diabetes, and Cancer
- Mycorrhizal Fungi and Plant Interactions
- Diet, Metabolism, and Disease
- Antibiotic Resistance in Bacteria
- Natural Antidiabetic Agents Studies
- Salmonella and Campylobacter epidemiology
- Insect symbiosis and bacterial influences
- Plant Pathogenic Bacteria Studies
- Fungal Biology and Applications
Institut Pasteur
2021-2024
Université Paris Cité
2021-2024
Fondazione Edmund Mach
2014-2019
Technische Universität Braunschweig
2017-2019
Helmholtz Centre for Infection Research
2017-2019
Abstract The Klebsiella group, found in humans, livestock, plants, soil, water and wild animals, is genetically ecologically diverse. Many species are opportunistic pathogens can harbour diverse classes of antimicrobial resistance genes. Healthcare-associated pneumoniae clones that non-susceptible to carbapenems spread rapidly, representing a high public health burden. Here we report an analysis 3,482 genome sequences 15 sampled over 17-month period from wide range clinical, community,...
Bacterial endophytes colonize the inner tissues of host plants through roots or discontinuities on plant surface, including wounds and stomata. Very little is known regarding a possible role insects in acquiring transmitting non- phytopathogenic microorganisms from to plant, especially those that are beneficial symbionts providing protection properties homeostatic stability host. To understand ecological transmission endophytic bacteria, we used freshly hatched nymphs American sap-feeding...
Endophytes hold great potential for implementing a more sustainable, bio-based agriculture. Here we investigated the differences among populations of endophytic bacteria isolated from wild and domesticated grapevines to improve our understanding how agriculture agro-environment affect communities. Bacterial isolates 88 that shared same climate at least four years were identified representative set 155 strains was characterized 30 features, including quorum sensing-related, enzyme production,...
The Klebsiella pneumoniae species complex (KpSC) is a major source of nosocomial infections globally with high rates resistance to antimicrobials. Consequently, there growing interest in understanding virulence factors and their association cellular metabolic processes for developing novel anti-KpSC therapeutics. Phenotypic assays have revealed diversity within the KpSC, but metabolism research has been neglected due experiments being difficult cost-intensive. Genome-scale models (GSMMs)...
The
Abstract The Klebsiella pneumoniae species complex (KpSC) is a set of seven taxa which are found in variety niches, and an important cause opportunistic healthcare-associated infections humans. Due to increasing rates multi-drug resistance within the KpSC, there growing interest better understanding biology metabolism these organisms inform novel control strategies. We collated 37 sequenced KpSC isolates isolated from representing all taxa. generated strain-specific genome scale metabolic...
Abstract The Klebsiella pneumoniae Species Complex (KpSC) is a major source of nosocomial infections globally with high rates resistance to antimicrobials. Consequently, there growing interest in understanding virulence factors and their association cellular metabolic processes for developing novel anti-KpSC therapeutics. Phenotypic assays have revealed diversity within the KpSC, but metabolism research has been neglected due experiments being difficult cost-intensive. Genome-scale models...