A5100442018- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- CRISPR and Genetic Engineering
- Advanced Biosensing Techniques and Applications
- Salmonella and Campylobacter epidemiology
- Lipid metabolism and biosynthesis
- Water Quality Monitoring and Analysis
- Cholinesterase and Neurodegenerative Diseases
- Breastfeeding Practices and Influences
- Luminescence and Fluorescent Materials
- Biofuel production and bioconversion
- Plant Pathogens and Resistance
- Food composition and properties
- Free Radicals and Antioxidants
- Analytical chemistry methods development
- Infant Nutrition and Health
- GABA and Rice Research
- Advanced Mathematical Physics Problems
- Cutaneous lymphoproliferative disorders research
- Microfluidic and Capillary Electrophoresis Applications
- Water Treatment and Disinfection
- Innovative Microfluidic and Catalytic Techniques Innovation
- Viral-associated cancers and disorders
- Melamine detection and toxicity
- Fatty Acid Research and Health
State Key Laboratory of Food Science and Technology
2023-2024
Nanchang University
2019-2024
Huaiyin Normal University
2023-2024
Wuhan Polytechnic University
2024
Northeast Agricultural University
2019-2023
Jiangsu University
2022
Jiangxi Provincial Cancer Hospital
2020
Jiangxi Provincial People's Hospital
2019-2020
Shanghai Research Institute of Chemical Industry
2017
Tianjin Medical University General Hospital
2016
The application of traditional lateral flow immunoassay (LFIA)-based gold nanoparticles (AuNPs) to measure traces target chemicals is usually challenging. In this study, we developed an integrated strategy based on molecular engineering and the spatial confinement (NPs) obtain ultrahigh quantum yields (QYs) aggregation-induced emission (AIE) fluorescence NPs employed them for highly sensitive detection T-2 toxin LFIA platform. Tetraethyl-4,4′,4″,4‴-(ethene-1,1,2,2-tetrayl)tetrabenzoate...
Ultrasensitive and quantitative fast screening of cancer biomarkers by immunochromatography test strip (ICTS) is still challenging in clinic. The gold nanoparticles (NPs) based ICTS with colorimetric readout enables a quick spectrum but suffers from nonquantitative performance; although fluorescence (FICTS) allows detection, its sensitivity deserves more efforts attentions. In this work, taking advantages FICTS, we described reverse enhancement (rFICTS) bimodal signal for ultrasensitive...
A figure-actuated microfluidic biosensor was developed for the rapid and sensitive detection of Salmonella typhimurium using immunomagnetic separation to separate target bacteria rolling circle amplification (RCA) combined with CRISPR/Cas12a amplify signal. The magnetic nanoparticles (MNPs) modified capture antibodies (MNPs@Ab1) RCA primer linked recognized (primer@Ab2) were first used react S. typhimurium, resulting in formation MNPs@Ab1-S. typhimurium-primer@Ab2 complexes. Then, reagents...
Respiratory tract infections (RTIs) pose a grave threat to human health, with bacterial pathogens being the primary culprits behind severe illness and mortality. In response pressing issue, we developed centrifugal microfluidic chip integrated recombinase-aided amplification (RAA)-clustered regularly interspaced short palindromic repeats (CRISPR) system achieve rapid detection of respiratory pathogens. The limitations conventional two-step CRISPR-mediated systems were effectively addressed...
Melamine (MEL), enrofloxacin (ENR), sulfamethazine (SMZ), tetracycline (TC), and aflatoxin M1 (AFM1) are the main chemical contaminants in milk. It is necessary to detect these miscellaneous milk synchronously ensure safety of In this study, a multiple lateral flow immunoassay (LFIA) was developed for detection MEL, ENR, SMZ, TC, AFM1 Under optimal experimental conditions, cutoff values were 25 ng/mL 1 2.5 0.25 samples. The limits LFIA 0.173 0.078 0.059 0.082 0.0064 AFM1. recovery rates...
Simultaneous contamination of ochratoxin A (OTA) and aflatoxin B1 (AFB1) in cereals are an ongoing global concern. For this reason, a sensitive method for the simultaneous detection OTA AFB1 soybean, corn, rice is required. Herein, we prepared bispecific monoclonal antibody (BsMAb) that specifically recognized AFB1, subsequently developed quantum dot nanobead (QB) lateral flow immunoassay (QB-LFIA) based on BsMAb. The half-inhibitory concentrations (IC50) were 0.73 0.01 µg/kg 1.14 0.03 1.69...
In this research, we explored their capacity for Narcissoside antioxidant and anticholinergic, antidiabetic, anti-acute myeloid leukaemia. Narcissoside's activities were elucidated by the use of various bioanalytical assays. radical scavenging evaluated DPPH• ABTS•+ activities. On other hand, IC50 values calculated DPPH•, scavenging, acetylcholinesterase, α-glucosidase inhibition effects narcissoside. narcissoside, as 11.54 nM AChE 65.58 with % Activity-[Inhibitory] graphs. Then, ADME/T...
1,3-Dioleoyl-2-palmitoylglycerol (OPO) is a kind of structured triglyceride which could instead human milk fat (HMF) for the infant formula, this good at absorbing easily. The aim paper was to produce OPO though three different processing technologies. raw material first method (Method 1) and second 2) palm oil, their catalyst Novozym 435 Lipozyme TL IM. difference Method 1, obtained tripalmitin (PPP) by acidolysis oil palmitic acid (PA), then PPP oleic (OA), 2 mixed fatty acids directly...
Human milk oligosaccharides (HMOs) have become a hot topic in the field of maternal and infant nutrition health research, are also widely used as innovative functional ingredients formulas, but their complex structure makes its isolation analysis difficult. This paper presents simple method for extraction HMOs. The effect presence lactose on determination HMO content was investigated by high-performance liquid chromatography-mass spectrometry (HPLC-MS). is dynamically enriched with using...
<title>Abstract</title> A methodology with rapidity and specificity is of great significance for effectively control management disease epidemics caused by <italic>Salmonella enterica</italic> as it has presented an obvious threat to food safety public health worldwide. One major drawback the traditional cross-priming amplification (CPA) detection method possibility detecting false-positive signals derived from opening tube lids or non-specific amplification, molecular beacon was firstly...
In this study, we develop a competitive ratiometric fluorescent lateral flow immunoassay (CRF-LFIA) based on dual emission fluorescence signal, which has great advantage in visual and quantitative detection of Chlorothalonil (CTN). Red-emitted magnetic nanobeads (FMNBs) green-emitted aggregation-induced microsphere (AIEFM) are synthesized conjugated to antibodies antigens respectively, resulting binding with the analyte. The signal comes from overlap these two emissions. FMNBs probes also...
To realize quantitative analysis without authentic standards by gas chromatography, a calculation method of effective carbon numbers (ECNs) was developed determining the relative response factors 66 alkanes, alcohols, ethers with GC-FID and studying relation between ECNs chemical structures. The correlation coefficient 0.9998 (N=66) achieved theoretical values experimental ECNs. Fifty-seven percent determined compounds had deviations within ±1% all them ±3%. This is as accurate common...
In this paper, by using the method called "asymptotic contractive process" on timedependent entire space, existence of time-dependent attractor for wave equation with decay coefficient 12 ( ) nn HL is obtained.