A5030732191- Reconstructive Surgery and Microvascular Techniques
- Organ and Tissue Transplantation Research
- Nerve injury and regeneration
- RNA and protein synthesis mechanisms
- Intraocular Surgery and Lenses
- Antimicrobial Peptides and Activities
- Glaucoma and retinal disorders
- Neurological Disorders and Treatments
- Biochemical and Structural Characterization
- Facial Nerve Paralysis Treatment and Research
- Photosynthetic Processes and Mechanisms
- Cancer Cells and Metastasis
- Breast Implant and Reconstruction
- Advanced Glycation End Products research
- Biochemical and biochemical processes
- Plant Parasitism and Resistance
- Prosthetics and Rehabilitation Robotics
- Cutaneous Melanoma Detection and Management
- Retinal Imaging and Analysis
- vaccines and immunoinformatics approaches
- Ophthalmology and Visual Impairment Studies
- Connexins and lens biology
- TGF-β signaling in diseases
- Wound Healing and Treatments
- Plant Reproductive Biology
Henan Agricultural University
2021-2025
Qingdao University
2018-2022
Qingdao Municipal Hospital
2018-2022
First Hospital of China Medical University
2008-2020
China Medical University
2008-2020
Jimo District Qingdao Hospital of Traditional Chinese Medicine
2020
Brigham and Women's Hospital
2015-2019
Harvard University
2015-2019
Huazhong Agricultural University
2018-2019
Fundación Juan March
2016
Abstract Noncanonical peptides (NCPs) are a class of generated from regions previously thought as noncoding, such introns, 5′ UTRs, 3′ and intergenic regions. In recent years, the significance diverse functions NCPs have come to light, yet systematic comprehensive NCP database remains absent. Here, we developed NCPbook (https://ncp.wiki/ncpbook/), evidence-supported NCPs, which aims provide resource for efficient exploration, analysis, manipulation NCPs. incorporates data public databases...
Multidrug-resistant (MDR) bacteria pose a major threat to public health, and additional sources of antibacterial candidates are urgently needed. Noncanonical peptides (NCPs), derived from noncanonical small open reading frames, represent biological molecules with important roles in biology. However, the activity NCPs remains largely unknown. Here, we discovered plant-derived peptide (NCBP1) against both Gram-positive Gram-negative bacteria. NCBP1 is composed 11 amino acid residues cationic...
To evaluate the potential risk factors of posterior capsule opacification (PCO) after cataract surgery. Data on PCO patients diagnosed from September 2015 to May 2017 were obtained Department Ophthalmology at Qingdao Municipal Hospital, Qingdao, China. The associated with assessed using Pearson's χ2 test for univariate analyses and logistic regression multivariate analyses. Eyes (652) 550 enrolled in this study. All PCO/non-PCO had <3 years follow-up numbers non-PCO 108 eyes 544 eyes,...
Stop codon readthrough (SCR) has important biological implications but remains largely uncharacterized. Here, we identify 1,009 SCR events in plants using a proteogenomic strategy. Plant candidates tend to have shorter transcript lengths and fewer exons splice variants than non-SCR transcripts. Mass spectrometry evidence shows that stop codons involved can be recoded as 20 standard amino acids, some of which are also supported by suppressor tRNA analysis. We observe multiple functional...
Melanoma is an aggressive type of cutaneous malignancy. Transforming growth factor (TGF)‑β has been demonstrated to be important mediator tumor progression. However, the best our knowledge, systemic roles plasma TGF‑β and in situ have not investigated Han Chinese melanoma patients. The results present study that levels TGF‑β1, TGF‑β2 TGF‑β3 protein messenger RNA were significantly elevated tissues compared with those normal tissues. survival rates patients which triple‑positive (TGF‑β1+,...
Abstract Stop codon readthrough (SCR), the decoding of a stop as sense by ribosome, has important biological implications but remains largely uncharacterized in plants. Here, we identified 1,009 SCR events two monocots (maize, rice) and dicots (soybean, Arabidopsis ) using proteogenomic strategy with 80 customized databases. transcripts were mostly significantly shorter had fewer components than non-SCR monocot plants, although these differences not significant dicots. Mass spectrometry...
Given the initial success of hand transplantation, there has been increased interest in determining functional independence and activities daily living after transplantation. However, metrics methodologies used to study these outcomes have not yet standardized. The goal this article was assess role video clips assessing bilateral We performed 3 transplantations at our institution. Video were taken standardized time points on index transplantation patient, patient sent multiple home-video...
Tracheocutaneous fistula (TCF) is the most common related post-operative complication after tracheotomy. Treatments such as surgery and flap grafting are usually applied to close TCFs. We report a case of large TCF with an area ~3.0 cm × 1.0 cm. Here, we describe relatively convenient approach for management patient TCF. In our treatment strategy, coverd tracheal stent was used cover defect by bronchoscopy, bronchial closed local turnover flap, structure reinforced biodegradable material...
Concurrent injuries to multiple extremities present unique challenges the reconstructive surgeon. The primary goal in such scenarios is optimize functional outcomes. of this article an overview various techniques necessary provide sufficient soft tissue and preserve amputation limb lengths function. concept innovative for maximizing savage function presented using index patient with extremity third- fourth-degree burn resulting nonsalvageable lower severe left-hand wounds. A review other...
Although rodent models have been used extensively for surgical research, their use is limited in microsurgical tissue transfer due to small size and the of vessels nerves. Also, fundamental anatomic differences may make hard extrapolate humans.In this report, authors present a rabbit model studying free nerve regeneration using innervated gracilis muscle flap. In providing are hopeful that could become standard investigative method future investigators employ other translational...
Maize (Zea mays L.) stalk rot is a devastating disease worldwide, causing severe yield losses. Although previous studies have focused on the genetic dissection of maize resistance to rot, mechanisms remain largely unknown. We used comparative proteomics approach identify candidate proteins associated with resistance. Statistical analyses revealed 763 differentially accumulated between Fusarium graminearum and mock-inoculated plants. Among them, antioxidant protein ZmPrx5, which was...
Objective To explore the application and clinical significance of serratus anterior muscle flap transfer in correction lateral part deformity expander to implant breast reconstruction. Methods Six patients who received expander-to-implant reconstruction were enrolled. After silicone replacing tissue expander, all 6 cases represented reconstructed breast. The turn-over was used as coverage deformed breast. Results Of (6 cases), aesthetics improved with incisions well-healed....