A5069107877- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet, Metabolism, and Disease
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Thyroid Disorders and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Medicinal plant effects and applications
- Diabetes Management and Research
- Growth Hormone and Insulin-like Growth Factors
- Blood Pressure and Hypertension Studies
- Regulation of Appetite and Obesity
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Nitric Oxide and Endothelin Effects
- Blood properties and coagulation
- Vitamin C and Antioxidants Research
- Diabetes Management and Education
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Urinary Bladder and Prostate Research
- Salivary Gland Disorders and Functions
- Natural Compound Pharmacology Studies
- Innovations in Medical Education
- Medical Education and Admissions
University of Ibadan
2016-2025
University College Hospital, Ibadan
1995-2022
Afe Babalola University
2019
Federal University of Technology
2018
University College Hospital
2013
University College London
2013
Bristol Royal Infirmary
2009
Objective: To assess adherence to medication among ambulatory patients with type 2 diabetes, ascertain the level of glycemic control, and evaluate patients' opinions on probable reasons for nonadherence a view identify areas intervention improve adherence.Methods: A prospective cross-sectional study was carried out at 900-bed tertiary teaching hospital in Ibadan, Southwestern Nigeria between June August, 2009.Out 140 consented patients, 114 (81.4%) properly responded validated pre-tested...
Objective. Oxidative stress (OS) has been implicated in the aetiology and progression of diabetic complications including foot ulcer. In this study, levels lipid peroxides (LPO) 8-hydroxy-2′-deoxyguanosine (8-OHdG) as well enzymatic antioxidant activities superoxide dismutase (SOD) glutathione peroxidase (GPx) type 2 diabetes mellitus ulcer subjects were assessed compared with apparently healthy normal to understand involvement OS subjects.Method. The abovementioned markers measured 50 for...
Abstract Background Maximum oxygen consumption is a measure of an individual’s cardiorespiratory fitness which singular predictor array diseases. Several exercise and non-exercise assessments are frequently compared to know method(s) provide the most accurate estimation aerobic capacity due difficulties in using direct method. There need if method right fit for population without huge overestimation or underestimation ethnical variation. This study was undertaken assess estimations healthy...
Objectives: Hypertension and type 2 diabetes are common comorbidities. Studies have shown that hypertension is twofold as in diabetic patients compared with non-diabetics. Excessive intake of dietary salt has reportedly caused increase blood pressure. This study investigated the effects high on rats. Materials Methods: Twenty-eight animals were randomly selected into four groups (n = 7). Group 1 (normal control), fed standard rats' feed; (diabetic streptozotocin-induced rats normal diet; 3...
Abstract Aim To determine the association between patients' characteristics, perception of family support and diabetes self‐management (DSM) behaviours among type 2 patients. Design A descriptive cross‐sectional design was used data were collected July–September 2016. The study is part a larger quasi‐experimental study. Methods One hundred ninety‐seven mellitus (DM) patients from two teaching hospitals in south‐west Nigeria participated. Questionnaire collecting information on...
Metabolic syndrome (MS) amplifies hypertension (HTN) associated with increased risk of cardiovascular disease (CVD). MS components and other CVD measures were investigated in different stages hypertension. 534 apparently healthy Nigerian traders aged 18–105 years participants a cohort study. The International Diabetes Federation (2005) the National High Blood Pressure Education Program Coordinating Committee criteria used for HTN classifications, respectively. Anthropometric indices obtained...
Gender is a major determinant of the outcomes many health interventions. This study documents order significant improvements in metabolic parameters patients with type 2 diabetes mellitus (T2DM) having syndrome within 12 weeks physical exercise programmes. Twenty-nine patients, mean age 49.6 ± 3.7 years, presenting high fasting plasma glucose, triglycerides, hypertension, and waist circumference undertook thrice weekly aerobic endurance programme addition to their drugs diet. Variables were...
There is evidence that nitric oxide (NO) modulates the metabolism of glucose and lipid, some antihypertensive medications have been shown to affect lipid metabolism. Peristrophe bivalvis a medicinal plant has properties. The study investigated effect aqueous extract leaf (APB) on fasting blood level (FBG) profile in rats pretreated with nitro-L-arginine methyl ester (L-NAME). Male Wistar (150–170 g, n=30) were randomly divided into two groups: control (CT, n=5) L-NAME (n=25). CT received 5...
Background: Metabolic Syndrome (MS) increases the risk of developing type-2 diabetes (DM2) and cardiovascular diseases (CVD) it is thought to be prevalent in Nigeria.This study aims at determining prevalence MS its component factors among apparently healthy traders a local market Ibadan, Nigeria.Methods: 534 from Bodija, Nigeria aged (18-105) years with neither DM2 nor CVD were participants cohort on assessment type 2 dementia Nigerians metabolic syndrome.The International Diabetes...
Electromagnetic fields have been reported to alter electrical activities in the brain and heart. However, there is paucity of information on potential functional alterations that magnetic from mobile phone could cause This study investigated heart rate variability (HRV), blood pressure (BP) lipid profile Wistar rats exposed electromagnetic field radiation a dual transceiver (DTrMP).Twenty-one male albino (140-180 g) were randomly assigned two major groups positioned 5 m apart as follows:...
Cardiometabolic syndrome has been linked with dietary modification. Therefore, we investigated the effects of D-ribose-L-cysteine (DRLC) in rats fed high fructose fat (HFHF) diet. Twenty (n = 5), divided into 4 groups were concurrently exposed to HFHF and/or DRLC (250 mg/kg, p.o) during 8 weeks study. The result showed that compared control group, group had significant impairment lipid and glucose homeostasis, increased cardiac xanthine oxidase, systolic blood pressure, heart rate, %body...
Reports about the impact of Carbon tetrachloride (CCl4) hepatotoxicity on coagulation profile have been inconsistent. Multiple investigators however demonstrated effectiveness silymarin in resolution anomalies induced by CCl4, although effect CCl4 hepatotoxicity, especially and osmotic fragility not investigated. The liver, primary site for secretion proteins, can become impaired reportedly increases hepatic protein synthesis as part its hepatoprotective mechanism. This study assessed blood...
Diets rich in fats and fructose are associated with the pathogenesis of oxidative stress-induced non-alcoholic fatty liver disease. Therefore, we investigated effect D-ribose-L-cysteine (DRLC) high-fructose high-fat (HFHF) diet-fed rats. Twenty rats (n = 5), divided into four groups, were simultaneously exposed to HFHF and/or DRLC (250 mg/kg) orally during 8 weeks study. Results showed that precipitated pro-inflammation selective disruption stress markers. There significant decreases level...
Diet is a key factor in the aetiology of many diseases, including metabolic syndrome and lower urinary tract disorders. Metabolic growing increasingly expensive health problem both developed developing world, with an associated rise morbidity mortality. On other hand, symptoms affect millions individuals worldwide, lowering their quality life. Associations have been established between conditions existing literature various components linked onset aggravation forms LUTS. This current review...
D-ribose-L-cysteine (DRLC) acts as a rate limiting substrate for the synthesis of glutathione (GSH). GSH deficiency has been linked to oxidative stress, hypertension and cardiovascular diseases. There are limited findings on effects DRLC in physiologic state. This study was therefore designed investigate different doses normal Wistar rats.Fifteen male rats were assigned into 3 groups (n = 5). Group 1 administered orally with 10 mg/kg distilled water (Control). Groups 2 125 250 respectively...
Diabetes mellitus is a common risk factor for erythrocyte osmotic stress. This study was aimed at exploring the effect of streptozotocin (STZ)-induced diabetes and salt-induced hypertension on fragility hemorheological variables in male Wistar rats. Thirty rats were grouped into five groups six animals each as follows: negative control (zero salt diet); positive (normal diet - 0.3% salt); high (8% salt) (HSD only); STZ induced normal (STZ + HSD). At end 4 weeks period, hematological...