A5101506327- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Cardiac, Anesthesia and Surgical Outcomes
- Assisted Reproductive Technology and Twin Pregnancy
- Cardiovascular Issues in Pregnancy
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Reproductive tract infections research
- Cardiac electrophysiology and arrhythmias
- Gestational Diabetes Research and Management
- Cardiac Arrhythmias and Treatments
- Maternal and fetal healthcare
- Ectopic Pregnancy Diagnosis and Management
- Takotsubo Cardiomyopathy and Associated Phenomena
- Atrial Fibrillation Management and Outcomes
- Pericarditis and Cardiac Tamponade
- Cardiac Imaging and Diagnostics
- Adolescent Sexual and Reproductive Health
- Reproductive Health and Contraception
- Pelvic floor disorders treatments
- Cardiac Structural Anomalies and Repair
- Kruppel-like factors research
- Fluoride Effects and Removal
- Ultrasound in Clinical Applications
- Ureteral procedures and complications
Rutgers, The State University of New Jersey
2024
Children's Hospital of Philadelphia
2021-2022
Texarkana College
2017-2021
St George's, University of London
2006-2019
University College Cork
2019
KLE Society Hospital
2018
Sir Ganga Ram Hospital
2018
St George’s University Hospitals NHS Foundation Trust
2010-2018
St George's Hospital
2017
University of Washington
2010-2016
Expedited partner therapy (EPT) has been shown to reduce the risk of persistent or recurrent gonorrhea and chlamydial infection in heterosexuals, increase proportion sex partners receiving treatment. The objective this analysis was evaluate consistency EPT's effect across sociodemographic behavioral subgroups.Subset analyses from a randomized controlled trial compared EPT standard referral (SPR) behaviorally defined subgroups. Outcomes included study participants participants' report that...
Uterine Artery Pseudoaneurysm is a rare cause of pelvic pain and haemorrhage in pregnancy. It should be considered the differential diagnosis pregnant women presenting with abdominal readily diagnosed by colour Doppler ultrasound. If left untreated, they may bleed into peritoneum causing severe haemorrhagic shock progress to maternal fetal death.We describe case woman right iliac fossa at 26 weeks gestation attributed uterine artery pseudoaneurysm on duplex ultrasound which was successfully...
Hematologic developmental norms from infant squirrel monkeys indicate a relative maturation of the hematopoietic system by 16 weeks. The elevated hemoglobin, hematocrit, red blood cell count, MCV and MCH at birth are followed decreasing hemoglobin (decreasing count MCV) until 4 weeks age. A reticulocytosis then occurs level approximates adult concentrations age with gradual changes in this as well thereafter. Total leukocytes segmented neutrophils decrease rapidly first 2 weeks, reaching...
Supplementation of squirrel monkeys with folic acid improved hematologic and folate status, maternal weight gain during pregnancy, infant birth weight. Thus the content in stock diet (1.4 microgram/g) did not meet requirement for pregnancy. Low plasma vitamin B12 values suggest that (22 ng/g) also was adequate. Changes supplementation are similar to those human subjects, indicating monkey is an appropriate model deficiency pregnancy man.
A 73-year-old man with history of pulmonary sarcoidosis was found to have runs non-sustained bidirectional ventricular tachycardia (BVT) two different QRS morphologies on a Holter monitor. Cardiac magnetic resonance delayed gadolinium imaging revealed region patchy mid-myocardial enhancement within the left basal inferolateral myocardium. An 18-fluorodeoxyglucose positron emission tomography (FDG-PET) showed increased uptake in same area, consistent active sarcoid, no septal involvement....
Persistent pulmonary hypertension (PH) causes significant mortality and morbidity in infants with congenital diaphragmatic hernia (CDH). Since vascular abnormalities CDH develop early during foetal development, we hypothesized that prenatal maternal administration of treprostinil, through its anti-remodelling effect, would improve the PH-phenotype nitrofen rat model CDH.In a dose-finding study normal, healthy pregnant rats, demonstrated target-range plasma treprostinil concentrations without...
Propofol is one of the most commonly used sedating agents in critical care units worldwide. It generally well tolerated and preferred for its pharmacokinetic profile. Here, we describe a rare devastating adverse effect propofol, propofol-related infusion syndrome.
Key content Acquired uterine artery and congenital arteriovenous malformations are rare but associated with intractable haemorrhage increased maternal morbidity mortality if not diagnosed early. A high index of suspicion is required to make a timely diagnosis. Haemorrhages resulting from acquired previous history obstetric or gynaecological surgery. Ultrasound can be key in diagnosing localising these lesions before angiography. Selective embolisation the treatment choice. Learning...
Abstract Background Excess abdominal adiposity cause metabolic disturbances, particularly in pregnancy. Methods of accurate measurement are limited pregnancy due to risks associated with these procedures. This study outlines a non-invasive methodology for the adipose tissue and determines intra- inter-observer reliability ultrasound (US) measurements two components (subcutaneous (SAT) visceral (VAT)) within pregnant population. Thirty women were recruited at end their first trimester, from...
Ectopic pregnancies are an important cause of morbidity and mortality in early pregnancy. This article presents up-to-date review the risk factors associated with tubal ectopic how these patients present. is crucial for midwives who may be conducting booking appointments at earlier gestations those working pregnancy units. The role transvaginal ultrasound as new diagnostic gold standard also explored. Management strategies outlined, including surge conservative treatment, long term...
A pregnant woman presented with increasing exertional dyspnea and was found to have complete heart block a junctional escape rhythm. The did not resolve exercise testing, suggesting infranodal disease. presumptive diagnosis of mild viral myocarditis made, having been exposed her toddler exanthem days before. After giving steroids preemptively accelerate fetal lung maturity several close observation, the AV resolved. She discharged in stable condition without need for temporary or permanent...
Abstract Normal placental development and angiogenesis are crucial for fetal growth maternal health during pregnancy. However, molecular regulation of has been difficult to study due a lack specific genetic tools that isolate the placenta from embryo yolk sac. To address this gap in knowledge we recently developed Hoxa13 Cre mice which is expressed allantois-derived cells, including endothelial stromal cells. Mice lacking transcriptional regulators Yes-associated protein (YAP) PDZ-binding...
CREG1 is a small glycoprotein predominantly localized in the endolysosomal system. In mouse heart, expression increases with age. We previously observed cardiac hypertrophy and ventricular non-compaction percentage of constitutive Creg1 knockout mice during neonatal stage. To elucidate physiological function we generated cardiomyocyte-specific (cm KO) knock-in KI) by crossing fl/fl Rosa hCREG1/hCREG1 Myh6-Cre mice, respectively. By 6 months age, cm KO developed severe myocardial interstitial...
alpha 1 antitrypsin deficiency is associated with predisposition to the development of pulmonary emphysema and childhood cirrhosis. There are two common alleles in European population, proteinase inhibitor (Pi) Z S. In addition, there rare Pinull or QO variants which can be difficult diagnose. A family assigned as having PiQO allele by AAT protein quantification isoelectric focusing was shown DNA sequencing have PiMheerlen mutation (Pro369-Leu). This highlights difficulties diagnosis PiQO.
Background: Cardiac insufficiency is a major co-morbidity in candidate selection for renal transplantation, and decision concomitant heart transplantation depends on the propensity of myocardial dysfunction to recover following transplantation.There paucity data regarding predictors recovery function transplantation.Methods: We reviewed 183 consecutive patients who underwent transplant (without transplant) at Cleveland Clinic from 2003-2010 had baseline post-transplant echocardiograms...