A5018511831- Adrenal Hormones and Disorders
- Colorectal Cancer Screening and Detection
- Pituitary Gland Disorders and Treatments
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Hormonal Regulation and Hypertension
- Colorectal and Anal Carcinomas
- Cancer Immunotherapy and Biomarkers
- Growth Hormone and Insulin-like Growth Factors
- Adrenal and Paraganglionic Tumors
- Cervical Cancer and HPV Research
- Genetic factors in colorectal cancer
- Stress Responses and Cortisol
- Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Nutrition and Health in Aging
- Diverticular Disease and Complications
- Body Composition Measurement Techniques
- Hepatitis B Virus Studies
- Neuroendocrine Tumor Research Advances
- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Digestive system and related health
- Hepatocellular Carcinoma Treatment and Prognosis
- Helicobacter pylori-related gastroenterology studies
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2013-2024
University of Turin
2011-2023
University of Buenos Aires
2023
Instituto de Química y Fisicoquímica Biológicas
2023
Consejo Nacional de Investigaciones Científicas y Técnicas
2023
University of L'Aquila
2020
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2019
Presidio Ospedaliero
2019
IRCCS Policlinico San Donato
2019
University of Kassel
2018
Cushing's syndrome is associated with several comorbidities responsible for the increased cardiovascular risk, not only during active phase but also after disease remission.In 29 patients (14 diseases and 15 adrenal adenomas), waist circumference, fasting 2-h glucose oral tolerance test (OGTT), lipid profile blood pressure were evaluated 1 year remission compared those in sex-, age- BMI-matched controls.During disease, OGTT, total LDL cholesterol higher than controls (P < 0·001) similar...
Journal Article Effect of house dust mite avoidance measures in children with atopic dermatitis Get access G. Ricci, Ricci Departments Paediatrics and Clinical Experimental Medicine, Division Dermatology, University Bologna, Via Massarenti 11, 40138 Italy Dr Giampaolo Ricci. E‐mail: ricci@med.unibo.it Search for other works by this author on: Oxford Academic Google Scholar A. Patrizi, Patrizi F. Specchia, Specchia L. Menna, Menna P. Bottau, Bottau V. D'Angelo, D'Angelo M. Masi British Volume...
We measured the accuracy of p16(INK4a)-Ki67 (CINtec PLUS, Roche, Mannheim, Germany), and E6/E7mRNA (types 16/18/31/33/45 NucliSENS easyQ, bioMérieux, Boxtel, The Netherlands) as triage test, alone combined with cytology.Six thousand two hundred seventy women were recruited in a population-based screening using HPV DNA primary test; 396 positive tested for cytology biomarkers. All tests performed on same sample. Cytology-positive referred to colposcopy; cytology-negative one-year re-testing....
Syndrome of inappropriate antidiuresis (SIAD) is the main cause hyponatremia in cancer patients. International guidelines indicate urea as an interesting option for chronic SIAD. Nevertheless, strong data to support its use are lacking, and role oncologic patients has not been described so far.We retrospectively analysed 36 affected by moderate or profound SIAD-induced hyponatremia, who started oral (initial daily dose 15 g 30 g) without fluid restriction between July 2013 2018. We mean...
Abstract Object Although glucocorticoids are essential for health, several studies have shown that replacement in Addison's disease might be involved anthropometric and metabolic impairment, with increased cardiovascular risk, namely if conventional doses used. As the effects of mediated by glucocorticoid receptor, encoded NR 3 C 1 gene, different polymorphisms gene been linked to altered sensitivity general population as well patients obesity or syndrome. Design We investigated impact...
Locally advanced rectal cancer (LARC) is a heterogeneous group of tumors where risk-adapted therapeutic strategy needed. Short-course radiotherapy (SCRT) more convenient option for LARC patients than preoperative long-course RT plus capecitabine. Histone-deacetylase inhibitors (HDACi) have shown activity in combination with and chemotherapy the treatment solid tumors. Valproic acid (VPA) an anti-epileptic drug HDACi anticancer activity. In preclinical studies, our showed that addition HDACi,...
Objective To assess the frequency of adverse events associated with periendoscopic management direct oral anticoagulants (DOACs) in patients undergoing elective GI endoscopy and efficacy safety British Society Gastroenterology (BSG) European Gastrointestinal Endoscopy (ESGE) recommendations (NCT 02734316). Design Consecutive on DOACs scheduled for were prospectively included. The timing DOAC interruption resumption before after procedures recorded, along clinical procedural data. Procedures...
We evaluated the performance of cytologic p16(INK4a) (p16) immunostaining within a cervical cancer screening program for categories atypical squamous cells undetermined significance (ASC-US) and low-grade intraepithelial lesion (LS after triage with high-risk human papillomavirus (HR-HPV) testing cells, cannot exclude high-grade (ASC-H) (HSIL). also verified whether routine introduction p16 staining might enhance specificity positive predictive value (PPV) neoplasia grade 2 or higher (CIN2+)...
Cushing Syndrome (CS) is implicated by increased cardiovascular risk (CVR) leading to morbidity and mortality. Oxidative stress (OS) platelet activation (PA) are associated with CVR. However, scarce data of OS in CS exist. Our objective was determine the oxidant-antioxidant balance CS.Fourteen patients at diagnosis fourteen healthy subjects (NS) were evaluated measuring plasma 15-F2t -Isoprostane (15-F2t -IsoP), PA thromboxaneB2 levels (TXB2 ), antioxidant reserve total capacity (TAC) serum...
Aim To compare acceptability and diagnostic accuracy of a recently available faecal immunochemical test (FIT) system (HM-JACKarc) with the FIT routinely used in an established screening programme (OC-Sensor). Design Randomised controlled trial ( ISRCTN20086618 ) within population-based colorectal cancer (CRC) programme. Subjects eligible for invitation Umbria Region (Italy) were randomised (ratio 1:1) to be screened using one systems. Results Screening uptake among 48 888 invitees was same...
Background Hypercortisolism accounts for relevant morbidity and mortality is often a diagnostic challenge clinicians. A prompt diagnosis necessary to treat Cushing’s syndrome as early possible. Objective The aim of this study was develop validate clinical model the estimation pre-test probability hypercortisolism in an at-risk population. Design We conducted retrospective multicenter case-control study, involving five Italian referral centers Endocrinology (Turin, Messina, Naples, Padua...
Objective To present the results of first and second round human papilloma virus (HPV)-based screening programme in Umbria region after three years. Methods From August 2010 to November 2011, entire female population aged 35–64 a local health district was invited for HPV testing (HPV-DNA cobas4800 on liquid-based cytology sample). HPV-negative women were re-invited For HPV-positive women, slide prepared interpreted. Positive cytologies referred colposcopy; negatives repeat one year. If...
Multimodal treatments for rectal cancer, along with significant research on predictors to response therapy, have led more conservative surgical strategies. We describe our experience of the sparing approach in cancer patients clinical complete (cCR) after neoadjuvant treatment. also specifically highlight and imaging criteria select watch wait strategy (w&w). Data came from 39 out 670 treated locally advanced between January 2016 until February 2020. The selection were a chemotherapy...