A5101820514- Epigenetics and DNA Methylation
- Spine and Intervertebral Disc Pathology
- Maternal and fetal healthcare
- Microtubule and mitosis dynamics
- Medical Imaging and Analysis
- RNA modifications and cancer
- Pregnancy and preeclampsia studies
- Asthma and respiratory diseases
- Intracranial Aneurysms: Treatment and Complications
- Pregnancy and Medication Impact
- Histone Deacetylase Inhibitors Research
- Meningioma and schwannoma management
- Acute Ischemic Stroke Management
- Insect Pest Control Strategies
- Viral-associated cancers and disorders
- Spinal Fractures and Fixation Techniques
- Musculoskeletal pain and rehabilitation
- Ovarian cancer diagnosis and treatment
- Mycobacterium research and diagnosis
- Assisted Reproductive Technology and Twin Pregnancy
- Cancer-related molecular mechanisms research
- Diet, Metabolism, and Disease
- Glutathione Transferases and Polymorphisms
- IL-33, ST2, and ILC Pathways
- Congenital Anomalies and Fetal Surgery
Jiangsu University
2025
Affiliated Hospital of Jiangsu University
2025
Shanghai Jiao Tong University
2021-2024
Shanghai Sixth People's Hospital
2021-2024
Second Affiliated Hospital of Zhejiang University
2018-2021
Harbin Medical University
2007-2011
Third Affiliated Hospital of Harbin Medical University
2007-2009
Twin pregnancies have a higher prevalence of intrahepatic cholestasis pregnancy (ICP) than single pregnancies. It is unknown whether in vitro fertilization-embryo transfer (IVF-ET) influences the fetal outcomes twin complicated by ICP. This study aimed to explore impact IVF-ET on perinatal ICP pregnancy. Clinical data from 142 pregnant women with were retrospectively analyzed, including 51 patients who conceived through (IVF group) and 91 spontaneous conception (SC group). Several...
Pancreatic cancer is a highly malignant digestive tumor. Glutamine metabolism one of the important sources tumors. N6-methyladenosine (m6A) modification plays key role in regulating tumor and holds promise as therapeutic target various cancers, including pancreatic cancer. Disrupting m6A regulation glutamine could impair growth, offering potential new strategies. However, functional modifications cancer, especially metabolism, remains poorly understood. The Cancer Genome Atlas (TCGA) dataset...
Abstract Background The pandemic influenza A (H1N1) virus emerged during 2009 and has spread worldwide. This can cause injuries to the lungs, liver, heart. However, data regarding whether this affect pancreatic islets are limited. We investigated effects of pneumonia on fasting plasma glucose (FPG) islet function, evaluated possible correlations between biochemical test results severity H1N1 pneumonia. Methods performed a retrospective analysis patients either diagnosed with or suspected...
Objective: To investigate the effects of Modic changes on fusion rate and cage subsidence after transforaminal lumbar interbody (TLIF). Methods: From January 2015 to 2018, a total 186 patients with degenerative disease who received instrumentation monosegmental TLIF single polyetheretherketone (PEEK) in Nanjing Drum Tower Hospital were retrospectively reviewed. Patients at level where was placed enrolled as group, remaining assigned into non-Modic group. Disk height, lordosis segmental...
Ovarian cancer is one of the most common cancers and can be treated with microtubule-targeting drugs. Checkpoint forkhead ring finger domains (CHFR) a protein implicated in sensitivity to Whereas CHFR downregulation, often promoter hypermethylation, has been identified large number tumor types, it not ovarian cancer. We therefore searched for downregulation primary tumors.Fresh tissues from 53 patients (test) normal 21 (control) were tested hypermethylation mRNA levels.The was...
Ovarian cancer is one of the most common cancers and can be treated with microtubule-targeting drugs. Checkpoint forkhead ring finger domains (CHFR) a protein implicated in sensitivity to Whereas CHFR downregulation, often promoter hypermethylation, has been identified large number tumor types, it not ovarian cancer. We therefore searched for downregulation primary tumors.Fresh tissues from 53 patients (test) normal 21 (control) were tested hypermethylation mRNA levels.The was...
Background: Carotid blowout syndrome (CBS) frequently occurs at the distal internal carotid artery (distal-ICA) in patients with nasopharyngeal carcinoma (NPC), and remedial treatments run a high risk for neurologic complications. A case-control study was conducted to evaluate safety efficacy of protective stent insertion distal-ICA prevent CBS NPC patients, comparison endovascular coil occlusion. Methods: total 28 consecutive from June 2019 December 2021 Shanghai Sixth People’s Hospital (a...
To compare the clinical effects of oblique lumbar interbody fusion (OLIF) and lateral (LLIF) in treatment degenerative disc disease spine.
Introduction: SKF-96365 is regarded as an inhibitor of receptor-mediated calcium ion (Ca 2+ ) entry. The current study aimed to explore the effects on murine allergic rhinitis (AR). Methods: Intranasal administration was performed OVA induced AR. Serum and nasal lavage fluid (NLF) from mice were harvested assay IgE inflammatory cytokines using ELISA method. Inflammatory cells counted analyzed in NLF. Nasal mucosa tissues collected used for HE staining, immunohistochemistry (IHC) real-time...
Herniation of the amniotic sac into peritoneal cavity or bladder is a rare but serious condition during pregnancy, which has not been reported in pored congenital uterine anomaly. Here, we report case to draw obstetricians' attention atypical rupture. A primigravida at 35 weeks gestation was admitted for upper abdominal pain. primary diagnosis rupture made after finding herniation through obstetric ultrasound. Exploration emergent cesarean section revealed symmetrical defect on horn. The...
Objective:To investigate the safety and effectiveness of ethmoid artery pedicled septal floor mucosal flap in repair postoperative cerebrospinal fluid leakage after transsphenoidal pituitary tumor surgery.Methods: The clinical data 6 patients with leak Department Otolaryngology Head Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Jiao Tong University School Medicine from June 2011 2022. In surgery, bilateral posterior arteries were sacrificed due endoscopic expanded approach, so...
Abstract Background: The aim of this study was to construct a robust stemness-related gene signature for predicting prognosis cervical squamous cell carcinoma (CSCC). Methods: Expression data the PCBC database-derived pluripotent stem (PSC) samples were collected using one-class logistic regression (OCLR) method calculate stemness indexes (mRNAsi) derived from TCGA dataset. Functions possible mRNAsi-related genes extracted through WGCNA then examined by enrichment analysis. Most...