Yanyan Xu

ORCID: 0000-0002-4890-3685
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About
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Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Colorectal Cancer Surgical Treatments
  • Pleural and Pulmonary Diseases
  • Advanced X-ray and CT Imaging
  • Gastric Cancer Management and Outcomes
  • Medical Imaging Techniques and Applications
  • Lung Cancer Treatments and Mutations
  • Advanced Neuroimaging Techniques and Applications
  • Spine and Intervertebral Disc Pathology
  • Circular RNAs in diseases
  • Cardiac Imaging and Diagnostics
  • Cerebrovascular and Carotid Artery Diseases
  • MicroRNA in disease regulation
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Spondyloarthritis Studies and Treatments
  • Medical Imaging and Pathology Studies
  • Inflammatory mediators and NSAID effects
  • Bone and Joint Diseases
  • Colorectal and Anal Carcinomas
  • Gut microbiota and health
  • Chronic Kidney Disease and Diabetes
  • Cancer-related molecular mechanisms research
  • Parasites and Host Interactions

China-Japan Friendship Hospital
2016-2025

Lu'an First People's Hospital
2025

Xuzhou Medical College
2018-2024

Second Hospital of Anhui Medical University
2015-2023

Anhui Medical University
2015-2023

First People's Hospital of Yunnan Province
2021

Kunming University of Science and Technology
2021

China Medical University
2016-2020

Hebei University of Engineering
2020

Affiliated Hospital of Hebei University
2020

Intravoxel Incoherent Motion MRI of Rectal Cancer: Correlation Diffusion and Perfusion Characteristics With Prognostic Tumor MarkersHongliang Sun1, Yanyan Xu1, Aiping Song2, Kaining Shi3 Wu Wang1Audio Available | Share

10.2214/ajr.17.18342 article EN American Journal of Roentgenology 2018-02-15

Renal fibrosis denotes a common complication of diabetic nephropathy and is predominant cause end-stage renal disease. Despite the association between microRNAs (miRNAs or miRs) fibrosis, miRNAs have been reported to play vital role in development chronic fibrosis. Therefore, aim present study was investigate possible function miR-101a Initially, microarray-based gene expression profiling employed screen differentially expressed genes. An vivo mouse model induced by unilateral ureteral...

10.1016/j.omtn.2020.01.002 article EN cc-by Molecular Therapy — Nucleic Acids 2020-01-17

Background Identification and staging of rectal cancer are mainly based on the difference in signal intensity (SI) between tumor normal structures intestinal wall T2-weighted imaging. However, differentiating stage pT0–T1 from pT2 tumors is difficult using routine magnetic resonance imaging (MRI) sequences. Purpose To summarize explore whether MRI findings can help differentiate tumors. Material Methods A total 110 patients with pT0–T2 underwent preoperative pelvic examinations resection...

10.1177/02841851251316435 article EN Acta Radiologica 2025-02-23

Background Many locally advanced rectal cancer (LARC) patients can benefit from neoadjuvant chemotherapy (NACT), with some achieving a pathological complete response (pCR). However, there is limited research reporting on the value of intravoxel incoherent motion (IVIM) in monitoring pCR LARC. Purpose To identify whether IVIM parameters derived whole‐tumor volume (WTV) before and after NACT could accurately assess Study Type Prospective patient control study. Population Fifty‐one LARC NACT,...

10.1002/jmri.25931 article EN Journal of Magnetic Resonance Imaging 2017-12-27

Abstract Background To investigate whether MRI findings, including texture analysis, can differentiate KRAS mutation status in rectal cancer. Methods Totally, 158 patients with pathologically proved cancers and preoperative pelvic examinations were enrolled. Patients stratified into two groups: wild-type group (KRAS wt group) mt according to genomic DNA extraction analysis. findings of (including features) relevant clinical characteristics statistically evaluated identify the differences...

10.1186/s12885-019-6341-6 article EN cc-by BMC Cancer 2019-11-14

The association between collagen type I alpha (COL1A) and chemoresistance has been verified in cancers. However, the specific role of COL1A2 gastric cancer (GC) cell resistance to apatinib, a highly selective small-molecule inhibitor vascular endothelial growth factor receptor 2, not investigated before. purpose this study was explore potential factors associated with regulation on GC apatinib vitro. With aid Oncomine database integrated bioinformatics methods, we identified overexpression...

10.1155/2022/5374262 article EN cc-by Analytical Cellular Pathology 2022-02-22

Circular RNA (circRNA) is a key regulator of cancer, and it has been proved to be involved in the regulation cancer progression including non-small cell lung (NSCLC). Circ-PITX1 was found significantly upregulated circRNA NSCLC, its role potential mechanism NSCLC deserve further investigation.The expression levels circ-PITX1, microRNA (miR)-1248 cyclin D2 (CCND2) were examined by quantitative real-time PCR (qRT-PCR). Cell proliferation, apoptosis, cycle process, migration invasion determined...

10.2147/ott.s286820 article EN OncoTargets and Therapy 2021-03-01

The aim of this study was to evaluate the short-term test-retest reproducibility diffusion-weighted magnetic resonance imaging (DW-MRI) parameters rectal cancer with 3.0T MRI.Twenty-six patients underwent MRI, including 8 b values. Apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM) (D, pure diffusion; f, perfusion fraction; D*, pseudodiffusion coefficient) were, respectively, calculated. reproducibility, intra interobserver variation IVIM were assessed based on...

10.1097/md.0000000000006866 article EN cc-by-nc Medicine 2017-05-01

The purpose of this study was to evaluate the usefulness intraprocedural CT and prior PET/CT fusion imaging in improving diagnostic yield CT-guided transthoracic core-needle biopsy (CNB) lung masses.In total, 145 subjects with masses suspicious for malignancy underwent image-guided CNB. According modality were divided into two groups. images obtained no more than 14 days before integrated images. or fused then used plan puncture sites. clinical characteristics, CNB, accuracy rate,...

10.1186/s12890-022-02108-6 article EN cc-by BMC Pulmonary Medicine 2022-08-13

Abstract Aim Previous studies have reported that monocyte chemoattractant protein–1 ( MCP –1) is involved in inflammatory and metabolic diseases. The purpose of this study to investigate the role –1 pathogenesis diabetic retinopathy DR ) Han Chinese patients with Type 2 diabetes. Methods Serum levels protein classified as without DWR , including NPDR PDR were assayed by enzyme‐linked immunosorbent assay. Genomic DNA from 198 patients, 176 143 genotyped using a PCR restriction fragment length...

10.1111/dme.12804 article EN Diabetic Medicine 2015-05-16

Abstract Background Diagnosing persistent pulmonary consolidation still faces challenges. The purpose of this study is to compare the diagnostic yield and complication rate between percutaneous transthoracic CT-guided coaxial needle biopsy (PTCNB) transbronchial lung (TBLB) consolidation. Materials From January 1, 2016, December 31, 2020, we have retrospectively enrolled a total 155 consecutive patients (95 males, 60 females) with who underwent both TBLB PTCNB. According standard reference,...

10.1186/s13244-023-01436-3 article EN cc-by Insights into Imaging 2023-05-11

Aberrant expression of Anillin (ANLN) has been shown to function in the development multiple cancers. However, its effects on colorectal carcinoma (CRC) remain unclear. We aimed explore role ANLN CRC development.By real-time quantitative polymerase chain reaction (RT-qPCR), Western blot, and immunohistochemistry (IHC), we assessed level tissues cell lines. The proliferation was evaluated by CCK-8 assays, colony formation EdU assays cycle assays. A mouse tumorigenic model established evaluate...

10.1080/08941939.2020.1850939 article EN Journal of Investigative Surgery 2021-03-23

To evaluate the feasibility and safety of microcoil in simultaneous localization for multiple pulmonary nodules before video-assisted thoracic surgery (VATS). Twenty-eight consecutive patients (26 two-nodule, 2 three-nodule; 58 total; Group A) underwent CT-guided VATS using microcoil. Successful targeting, localization, were defined as implantation at target site on CT image which was obtained immediately after marking procedure, visualization nodule location, complete resection with...

10.1186/s12890-021-01393-x article EN cc-by BMC Pulmonary Medicine 2021-01-25
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