A5019846084- Diabetes and associated disorders
- Adolescent and Pediatric Healthcare
- Immunodeficiency and Autoimmune Disorders
- Microscopic Colitis
- Celiac Disease Research and Management
- Inflammatory Bowel Disease
- Liver Diseases and Immunity
- Emergency and Acute Care Studies
- Infant Nutrition and Health
- Child Nutrition and Water Access
- Immune Cell Function and Interaction
- Autoimmune and Inflammatory Disorders Research
- Patient Satisfaction in Healthcare
- Conferences and Exhibitions Management
- Child Nutrition and Feeding Issues
- Antibiotic Use and Resistance
- Obesity, Physical Activity, Diet
- Gastroesophageal reflux and treatments
- Gut microbiota and health
- Eosinophilic Esophagitis
- Digestive system and related health
Tampere University Hospital
2021-2025
Queensland Children’s Hospital
2025
Tampere University
2021-2025
Folkhälsans Forskningscentrum
2023-2025
Finnish Institute for Health and Welfare
2021
University of Eastern Finland
2021
Helsinki Art Museum
2021
University of Helsinki
2021
Children's eating behaviors, including a tendency towards overeating, are strongly influenced by the family. Children prone to overeating at high risk of excessive weight gain, which can lead further adverse health outcomes. Therefore, identifying factors that contribute is crucial for promoting healthy development. Given inconsistencies in previous research, mostly involving young children, we investigated child and parental characteristics associated with preadolescence. The...
Objectives Atypical ulcerative colitis (UC) presenting reverse gradient colitis, backwash ileitis, or rectal sparing and/or positive atypical antineutrophil cytoplasmic antibody serology is often associated with primary sclerosing cholangitis (PSC) and can be resistant to conventional medical therapies (CMT) for inflammatory bowel diseases. We report short-term long-term outcomes of oral vancomycin therapy (OVT) in children UC confirmed PSC imaging/biopsy (PSC-UC) treatment-resistant without...
Abstract Type 1 diabetes mellitus (DM), autoimmune thyroiditis (AIT), juvenile idiopathic arthritis (JIA), and inflammatory bowel diseases (IBD) are common pediatric with unknown risk factors. Using nationwide registers, we searched for their perinatal Our study followed up 11,407 children (born 2000–2005) a median of 16.6 years (from birth to 2018). Of them, 2.15% received primary diagnosis 0.08% also secondary: 0.89% had DM, 0.60% AIT, 0.48% JIA, 0.25% IBD. The incidences per 100,000...
The incidences of both paediatric obesity and autoimmune diseases have been increasing, but their relationship with one another is unclear.To determine whether or particular dietary patterns in school-aged children are potential risk factors for during adolescence.This matched case-control study included 525 children, followed up from a median age 11.3 to 16.7 years. Of them, 105 received primary diagnoses (diabetes, thyroiditis, arthritis, inflammatory bowel diseases) after baseline...
Proton pump inhibitors (PPIs) have been associated with decreased gut microbiota diversity. Disrupted composition has reported in several autoimmune diseases (ADs), such as type 1 diabetes mellitus (DM), thyroiditis (AIT), juvenile idiopathic arthritis (JIA), and inflammatory bowel (IBD). We investigated whether PPIs are the development of ADs children concluded that PPI exposures could be related to onset ADs, especially IBD potentially AIT well.
It is difficult to draw conclusions about the prudence of antibiotic use in different hospitals by directly comparing usage figures. We present a patient case-mix adjustment model rank while taking characteristics into account.Data on were collected during national healthcare-associated infection (HAI) prevalence survey 2005 Finland all 5 tertiary care, 15 secondary care and 10 (25% 40) other acute hospitals. The antibiotics was measured using use-days/100 patient-days 7day period patients...
Abstract Background Antibiotics have been associated with several individual autoimmune diseases (ADs). This study aims to discover whether pre-diagnostic antibiotics are the onset of ADs in general. Methods From a cohort 11,407 children, 242 developed (type 1 diabetes, thyroiditis, juvenile idiopathic arthritis (JIA), or inflammatory bowel diseases) by median age 16 years. Antibiotic purchases from birth until date diagnosis (or respective matched controls n = 708) were traced national...
Biological treatments (BTs) are essential in managing pediatric inflammatory bowel diseases (PIBDs). Elevated liver enzymes sometimes succeed BT, yet elucidating studies scarce. We addressed biochemistry after introducing BT and searched for their determinants.
Altered commensal microbiota composition has been associated with pediatric type 1 diabetes mellitus (T1D) and inflammatory bowel diseases (IBD), but the causal relationship is still unclear. To search for potential pre-diagnostic biomarkers T1D or IBD, we compared in saliva samples a nested case-control design comprising children developing (nchildren = 52) IBD 21) controls similar age, sex, residential area 79). The alpha- beta-diversity of who would develop (nsamples 27) 14) minimally...
Abstract Incidences of pediatric autoimmune diseases (ADs) have been increasing without clearly identified environmental risk factors. Using national registers (special reimbursement and drug purchase register), this matched case-control study aims to discover whether antibiotic exposures are related development ADs in general. From a cohort 11,407 children (born 2000-2005, followed-up until December 2018), 242 with (type 1 diabetes (DM), thyroiditis (AIT), juvenile idiopathic arthritis...