A5039950111- Psoriasis: Treatment and Pathogenesis
- Inflammatory Bowel Disease
- Health Systems, Economic Evaluations, Quality of Life
- Microscopic Colitis
- Eosinophilic Esophagitis
- Pregnancy and Medication Impact
- Rheumatoid Arthritis Research and Therapies
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Dermatology and Skin Diseases
- Obesity and Health Practices
- Complementary and Alternative Medicine Studies
- Cholinesterase and Neurodegenerative Diseases
- Systemic Lupus Erythematosus Research
- Chronic Lymphocytic Leukemia Research
- Pesticide Exposure and Toxicity
- Autoimmune and Inflammatory Disorders Research
- Patient Satisfaction in Healthcare
- Venous Thromboembolism Diagnosis and Management
- Alzheimer's disease research and treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Peptidase Inhibition and Analysis
- Cancer Immunotherapy and Biomarkers
- Antibiotic Use and Resistance
- Safe Handling of Antineoplastic Drugs
University of Turku
2000-2024
Turku University Hospital
2013-2024
Kainuun keskussairaala
2018
Central Finland Health Care District
2017
FinnMedi (Finland)
2000
Tampere University Hospital
2000
Tampere University
2000
Alzheimer9s disease (AD) and Parkinson9s (PD) are genetically heterogeneous. Dipeptidyl carboxypeptidase 1 (<i>DCP1</i>) butyrylcholinesterase (<i>BCHE</i>) genes may modify the risk of these disorders. We investigated whether common polymorphisms present in operate as factors for AD PD Finnish subjects, independently or concert with apolipoprotein E ε4 allele (<i>APOE </i>ε4). Eighty late onset sporadic patients, 53 patients (34 whom had concomitant pathology), 67 control subjects were...
Psoriasis has an influence on various aspects of patients' everyday life. When estimating the total burden disease, leisure-time should also be taken into account. To evaluate perceived impact psoriasis activities. The questionnaire study was based 262 patients with psoriasis. were asked to list their activities, any activities they had reduced or given up completely because psoriasis, time spent current and would have in a hypothetical situation if did not Using visual analogue scale (VAS)...
Work disability remains a considerable problem for many patients with rheumatoid arthritis (RA). Morning stiffness is symptom of RA associated early retirement from work and impaired functional ability. We aimed to explore the patient's perception impact morning on working life RA. A survey was conducted in 11 European countries. Patients age, ≥6 months ≥3 mornings week, were interviewed by telephone using structured questionnaire. Responses assessed total sample subgroups defined severity...
Psoriasis results in expenses to patients from many cost sources. treatments may result considerable time and traveling costs, yet studies fail account for these costs. The objective of this study was evaluate the multidimensional economic burden psoriasis patients.The based on 232 Finnish with or psoriatic arthritis visiting a tertiary level dermatological clinic during 1-year period between October 1, 2009 September 30, 2010. data were patient questionnaire, clinical medical records...
In previous studies, productivity losses have been measured specifically due to psoriasis or generally health problems in patients. There is no information on the proportion of related that are psoriasis. The aim this study was estimate and other medical among employed patients.Patients visiting a tertiary level dermatological clinic during one-year period arthritis, who were employed, selected study. A questionnaire used assess month.Psoriasis accounted for 38% total lost costs. One fifth...
Inflammatory bowel disease (IBD), consisting of Crohn's and ulcerative colitis, can be a lifelong burden generating high costs to an economic system. Data regarding the cost workplace presenteeism absenteeism in workers with IBD are limited. Our objective was assess these employed adults.A structured questionnaire, hospital records national registers were combined involved patients. final sample comprised 320 The calculated as productivity-loss by using Human Capital Approach.Due IBD, mean...
It is difficult to draw conclusions about the prudence of antibiotic use in different hospitals by directly comparing usage figures. We present a patient case-mix adjustment model rank while taking characteristics into account.Data on were collected during national healthcare-associated infection (HAI) prevalence survey 2005 Finland all 5 tertiary care, 15 secondary care and 10 (25% 40) other acute hospitals. The antibiotics was measured using use-days/100 patient-days 7day period patients...
Previous research indicates that psoriasis has an impact on early retirement, sick leave days and reduced work performance. To evaluate the disadvantages at caused by psoriasis. The sample was based patients visiting dermatology outpatient clinic in Turku University Hospital. 262 returned a mailed questionnaire. subjects were asked how many hours they (absenteeism) working while (presenteeism) due to other health reasons. Of retired, 17.0% felt retired Those active force reported average 4.5...
The costs of psoriasis to a tertiary-level clinic vary considerably depending on the country study and methods used. Hospitalisation phototherapy have been significant cost components. This was performed estimate distribution relative magnitude clinic. Based 233 patients, outpatient visits days hospitalised were collected from treatment provider's records. visit represented true costs, used charge final payers. Patients analysed according their modalities. On average, patients (3.4%) had...
Psoriasis is a chronic disease, which contributes to the economic burden on health care. The distribution of psoriasis medication costs and quality life in these patients has been estimated be around 20% total costs.To estimate medications impact multiple treatment options patient's life.The study was based 236 Finnish patients. Social Insurance Institution had databases for all related purchased. Each purchase, during 1-year period (1 October 2009-30 September 2010), recorded analyzed....
Previous studies have shown that psoriasis has a significant effect on patients' health-related quality of life. The impact household chores and the need for assistance with such tasks are not well documented. aim this study was to estimate ability carry out chores, time spent skin care at home patients require these activities.In questionnaire 262 moderate-to-severe psoriasis, visiting tertiary level dermatological clinic during 1-year period, listed which they considered were particularly...
Inflammatory bowel disease (IBD), mainly Crohn's (CD) and ulcerative colitis (UC) are chronic diseases causing a lifelong burden often need sustained treatment throughout patient's life. Both the incidence prevalence of IBD has increased in last decade. Evidence showing drug costs to patients Finland is limited. No earlier study evaluated Finland. Here, we thoroughly assessed these costs.A structured questionnaire, hospital records national registers were combined comprehensively assess...
The aim of this study was to explore the multifaceted ways in which inflammatory bowel disease (IBD) negatively affects working life and studies.
Inflammatory bowel disease, consisting of Crohn's disease and ulcerative colitis, is known to negatively impact an individual's quality life. Leisure-time activities are important part life by creating strengthening social networks. The aim this study was thoroughly evaluate the perceived inflammatory on leisure-time quantifying limitations in caused disease.A structured questionnaire, hospital records national registers were combined assess a patient's activities. final sample 561...
More than a half of inflammatory bowel disease (IBD) patients experienced moderate negative effect on their household chores due to IBD. The was more common amongst women.
<h3>Background</h3> RA has a substantial societal effect in terms of costs, disability and lost productivity, with much the costs occurring outside healthcare system (1,2). However, calculatedcosts vary considerably depending on countries studied methods used (3). <h3>Objectives</h3> The objective this study wasto evaluate influence morning stiffness productivity at work to estimate work-related economic consequences 11 European countries. <h3>Methods</h3> original sample comprised 1061...