A5002536186- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Respiratory viral infections research
- Pancreatic and Hepatic Oncology Research
- Cancer Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pneumonia and Respiratory Infections
- Cystic Fibrosis Research Advances
- COVID-19 and healthcare impacts
- Cancer Genomics and Diagnostics
- Colorectal and Anal Carcinomas
- SARS-CoV-2 and COVID-19 Research
- Peptidase Inhibition and Analysis
- Congenital Diaphragmatic Hernia Studies
- Cancer Immunotherapy and Biomarkers
- Tracheal and airway disorders
- Neonatal Respiratory Health Research
Schneider Children's Medical Center
2014-2024
Tel Aviv University
2000-2024
Sheba Medical Center
2014-2023
Ariel University
2021
Rabin Medical Center
2004-2017
Tel Aviv Sourasky Medical Center
2000-2015
Sorbonne Université
2015
Hadassah Medical Center
2011-2013
University Medical Center
2012-2013
Western General Hospital
2012
Purpose The MOSAIC (Multicenter International Study of Oxaliplatin/Fluorouracil/Leucovorin in the Adjuvant Treatment Colon Cancer) study has demonstrated 3-year disease-free survival (DFS) and 6-year overall (OS) benefit adjuvant oxaliplatin stage II to III resected colon cancer. This update presents 10-year OS DFS by mismatch repair (MMR) status BRAF mutation. Methods Survival actualization after follow-up was performed 2,246 patients with We assessed MMR mutation 1,008 formalin-fixed...
Systematic data are lacking on pediatric long COVID. This study prospectively assessed 90 children with persistent symptoms who presented to a designated multidisciplinary clinic for In nearly 60%, were associated functional impairment at 1–7 months after the onset of infection. A comprehensive structured evaluation revealed mild abnormal findings in approximately half patients, mainly respiratory aspect.
We examined the rate, clinical impact, and risk factors of cytomegalovirus (CMV) drug resistance in 561 patients who underwent 616 hematopoietic stem cell transplantations (HSCTs) over 5 years. Drug was exclusively identified haploidentical (haplo)-HSCT recipients receiving preemptive therapy, among whom rate 14.5%. Resistance appeared after prolonged treatment (median, 70 days), associated with higher preceding viral load (P < .001), strongest predictor for disease by multivariate analysis....
Trials of the Pfizer-BioNTech BNT162b2 mRNA vaccine showed 95% efficacy in preventing symptomatic disease; however, trials excluded immunocompromised patients (ICPs). We aim at analyzing antibody response ICPs.
Patients with cancer are at an increased risk for severe coronavirus disease of 2019, thus data on the safety and efficacy acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccines essential. We conducted this prospective study patients vaccinated BNT162b2 monitored antibody response safety. The aim was to evaluate rate seropositivity define predictors non-reactive immune response. Furthermore, we evaluated frequency severity adverse events.The included solid tumours undergoing...
Abstract Background Prognosis of patients following resection CRC metastases to the liver has traditionally been predicted by clinical risk factors. In era neoadjuvant chemotherapy, determination new prognostic indicators outcome are necessary. Methods This retrospective study includes with metastases, who received oxaliplatin or irinotecan based chemotherapy and underwent R0 resection. Patients were followed CT PET‐CT, before, during after surgery. The predictive value Memorial...
Abstract Background Respiratory syncytial virus (RSV) bronchiolitis is the most common lower respiratory tract disorder causing hospitalization in infants. Due to decreased rates of premature infants following Palivizumab immune prophylaxis, proportion with chronic diseases not eligible for has increased. Aim To characterize hospitalized during 2014–2018 RSV bronchiolitis, compare between those and without conditions, identify risk factors severe disease. Methods This retrospective study...
3504 Background: The management of unresectable metastatic colorectal cancer (mCRC) is a comprehensive treatment strategy involving several lines therapy, maintenance, salvage surgery, and treatment-free intervals. Besides chemotherapy (fluoropyrimidine, oxaliplatin, irinotecan), anti-angiogenic anti-epidermal growth factor receptor (EGFR) agents have become available. Ultimately, trials are needed to define the optimal use best sequencing these agents. Methods: Patients with previously...
Laser treatment for malignant dysphagia is limited by recurrent intraluminal tumour requiring repeated at four to eight week intervals.To reduce the need follow up and improve survival, patients successfully palliated laser were treated with radiotherapy.32 inoperable oesophageal carcinoma (18 adeno 14 squamous cell carcinoma).The initially a median of three treatments. They then radiotherapy, receiving 10-15 Gy 1 cm from source as single Selectron system. Patients also received external...
During the pandemic (H1N1) 2009 outbreak in Israel, incidence rates among children were 2× higher than that of previous 4 influenza seasons; hospitalization 5× higher. Children hospitalized for older and had more underlying chronic diseases those seasonal influenza.
The identification of the cystic fibrosis transmembrane conductance regulator ( CFTR ) gene and CF-causing variants has led to development therapies correct basic cellular defect. modulators (CFTRm) are such that either protein misfolding (correctors) or restore cell surface channel activity (potentiators) [1, 2]. Footnotes This manuscript recently been accepted for publication in ERJ Open Research . It is published here its form prior copyediting typesetting by our production team. After...
3509 Background: The therapeutic impact of Bev plus either FOLFOX4 or XELOX in the adjuvant setting was evaluated AVANT trial. First efficacy findings were presented at ASCO GI 2011. Here we present results subgroup analyses. Methods: Eligible pts underwent resection for resected high-risk stage II III CC. Pts randomly assigned to 1 3 treatment groups and stratified by geographic region tumor stage: Arm A: w1–24; B: + w1–24, then alone w25–48; C: w25–48. primary endpoint disease-free...
CD24 is expressed in 90% of colorectal adenomas and adenocarcinomas. Colorectal cancer (CRC) can be mostly prevented but average risk population screening by stool testing or colonoscopy faces many hurdles. Blood clinically needed. We aimed to evaluate the utility expression peripheral blood leukocytes (PBLs). Two independent case studies were conducted eligible individuals undergoing colonoscopy. Protein extracted from PBLs was subjected immunoblotting using anti-CD24 monoclonal antibodies....
The current study examined illness cognition-thoughts and perceptions-patients hold regarding their psychological adaptation in various age groups. More specifically, we aimed to examine whether cognition among cancer patients is related age. In addition, such association of was also with respect subjective well-being distress. A cross-sectional sample comprised 123 consecutive post-treatment gastric outpatients. Their mean 57.31 (SD = 12.74), 56.9% (n 70) were men 81.3% 100) married....
<h3>Background:</h3> During the Coronavirus disease 2019 (COVID-19) pandemic, wearing facemasks became obligatory worldwide. <h3>Objectives:</h3> The objective of this study was to evaluate effects on gas exchange. <h3>Methods:</h3> Healthy adults were assessed at rest and during slow brisk 5-minute walks, with without masks. We monitored O<sub>2</sub> saturation, end-tidal carbon dioxide (EtCO<sub>2</sub>), heart respiratory rates. Participants graded their subjective difficulty completed...