Nini de Boer
A5043524451- Schizophrenia research and treatment
- Diet and metabolism studies
- Diabetes Treatment and Management
- Alcohol Consumption and Health Effects
- Pharmaceutical Practices and Patient Outcomes
- Peripheral Neuropathies and Disorders
- Pharmacovigilance and Adverse Drug Reactions
- Bipolar Disorder and Treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Substance Abuse Treatment and Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- Parkinson's Disease Mechanisms and Treatments
- Digital Mental Health Interventions
- Smoking Behavior and Cessation
- Obsessive-Compulsive Spectrum Disorders
- COVID-19 and Mental Health
- Autoimmune Neurological Disorders and Treatments
- Telemedicine and Telehealth Implementation
University Medical Center Utrecht
2021-2025
Utrecht University
2021-2025
Clozapine is highly effective for treatment-resistant schizophrenia but underutilized due to patient and clinician-related concerns. Little known about the general level of satisfaction with clozapine determinants thereof. We therefore explored in individuals diagnosed spectrum disorders (SSDs). Cross-sectional data from 480 users were used examine demographic clinical factors, including symptom severity, treatment response, adverse drug reactions (ADRs). Patient was self-rated on a scale 1...
Clozapine is often underused due to concerns about adverse drug reactions (ADRs) but studies into their prevalences are inconclusive. We therefore comprehensively examined of clozapine-associated ADRs in individuals with schizophrenia and demographic clinical factors associated occurrence. Data from a multi-center study (n=698 participants) were collected. The mean number during clozapine treatment was 4.8, 2.4% participants reporting no ADRs. most common hypersalivation (74.6%), weight gain...
Previous studies into mental health service utilisation during the COVID-19 pandemic are limited to a few countries or specific type of service. In addition, data on changes in telepsychiatry currently lacking.We aimed investigate whether is associated with utilisation, including telepsychiatry, and how these were distributed among patients illness first outbreak.This retrospective study obtained routinely assessed healthcare from large Dutch institute. Data second quarter 2020 (the outbreak...
Alcohol consumption, smoking and mood disorders are leading contributors to the global burden of disease highly comorbid. Yet, their interrelationships have remained elusive. The aim this study was examine multi-cross-sectional longitudinal associations between (change in) alcohol use number depressive symptoms.In prospective, study, 6646 adults from general population were included with follow-up measurements after 3 6 years. Linear mixed-effects models used test associations, behaviour,...
Abstract Background Antipsychotic-induced Weight Gain (AiWG) is a debilitating and common adverse effect of antipsychotics. AiWG negatively impacts life expectancy, quality life, treatment adherence, likelihood developing type-2 diabetes readmission. Treatment currently challenging, there no consensus on the optimal management strategy. In this study, we aim to evaluate use metformin for by comparing with placebo in those receiving as usual, which includes lifestyle intervention. Methods...